scholarly journals Long-latency Reflexes and Area Measurements of Corpus Callosum in Patients with Multiple Sclerosis

2016 ◽  
Vol 4 (1) ◽  
pp. 5-11
Author(s):  
Hulya ERTASOGLU TOYDEMIR ◽  
Munevver GOKYIGIT ◽  
Feray KIYMAZ SELEKER ◽  
Lale GUNDOGDU CELEBI ◽  
Ender UYSAL ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Corpus Callosum ◽  
Long Latency ◽  
Long Latency Reflexes

P321: The role of long latency reflexes and area measurements of corpus callosum in the assessment of multiple sclerosis

2014 ◽  
Vol 125 ◽  
pp. S134
Author(s):  
H. Ertasoglu Toydemir ◽  
M. Gokyigit Celik ◽  
E. Uysal ◽  
L. Gundogdu Celebi
Keyword(s):  
Multiple Sclerosis ◽  
Corpus Callosum ◽  
Long Latency ◽  
Long Latency Reflexes

scholarly journals Cortical Relay Time for Long Latency Reflexes in Patients with Definite Multiple Sclerosis

2004 ◽  
Vol 31 (2) ◽  
pp. 229-234 ◽  
Author(s):  
Cengiz Tataroglu ◽  
Ahmet Genc ◽  
Egemen Idiman ◽  
Raif Cakmur ◽  
Fethi Idiman
Keyword(s):  
Multiple Sclerosis ◽  
Evoked Potentials ◽  
Somatosensory Evoked Potentials ◽  
Motor Evoked Potentials ◽  
Clinical Form ◽  
Control Subjects ◽  
Long Latency ◽  
Cortical Involvement ◽  
And Control ◽  
Long Latency Reflexes

AbstractBackground:Long latency reflexes (LLR) include afferent sensory, efferent motor and central transcortical pathways. It is supposed that the cortical relay time (CRT) reflects the conduction of central transcortical loop of LLR. Recently, evidence related to the cortical involvement in multiple sclerosis (MS) has been reported in some studies. Our aim was to investigate the CRT alterations in patients with MS.Methods:Upper extremity motor evoked potentials (MEP), somatosensory evoked potentials (SEP) and LLR were tested in 28 patients with MS and control subjects (n=22). The patients with MS were classified according to the clinical form (relapsing-remitting [R-R] and progressive groups). The MS patients with secondary progressive and primary progressive forms were considered as the “progressive” group. CRT for LLR was calculated by subtracting the peak latency of somatosensory evoked potentials (SEP) and that of motor evoked potentials (MEP) by transcranial magnetic stimulation from the onset latency of the second component of LLR (LLR2) (CRT = LLR2 – [MEP latency + N20 latency])Results:Cortical relay time was calculated as 7.4 ± 0.9 ms in control subjects. Cortical relay time was prolonged in patients with MS (11.2 ± 2.9 ms) (p<0.0001). The latencies of LLR, MEP and SEP were also prolonged in patients with MS. Cortical relay time was not correlated with disease severity and clinical form in contrast to other tests.Conclusions:Our findings suggested that CRT can be a valuable electrophysiological tool in patients with MS. Involvement of extracortical neural circuits between sensory and motor cortices or cortical involvement due to MS may cause these findings.

The diagnostic significance of long-latency reflexes in multiple sclerosis

1988 ◽  
Vol 70 (1) ◽  
pp. 56-61 ◽  
Author(s):  
Günther Deuschl ◽  
Kai Strahl ◽  
Eduard Schenck ◽  
Carl H. Lücking
Keyword(s):  
Multiple Sclerosis ◽  
Diagnostic Significance ◽  
Long Latency ◽  
Long Latency Reflexes

Interhemispheric transfer evaluation in multiple sclerosis 1The authors would like to thank Claude-Alain Hauert and Christoph Michel for their assistance in the evaluation of motor tapping and Michel Habib for his suggestions and comments. This work was supported by a grant from the Swiss Society of Multiple Sclerosis.

2000 ◽  
Vol 59 (3) ◽  
pp. 150-158 ◽  
Author(s):  
Nadia Ortiz ◽  
Michael Reicherts ◽  
Alan J. Pegna ◽  
Encarni Garran ◽  
Michel Chofflon ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Corpus Callosum ◽  
Lexical Decision ◽  
Dichotic Listening ◽  
Neurological Impairment ◽  
Interhemispheric Transfer ◽  
Decision Task ◽  
Swiss Society ◽  
Listening Test ◽  
Relapsing Remitting

Patients suffering from Multiple Sclerosis (MS) have frequently been found to suffer from damage to callosal fibers. Investigations have shown that this damage is associated with signs of hemisphere disconnections. The aim of our study was to provide evidence for the first signs of interhemispheric dysfunction in a mildly disabled MS population. Therefore, we explored whether the Interhemispheric Transfer (IT) deficit is multi-modal and sought to differentiate two MS evolution forms, on the basis of an interhemispheric disconnection index. Twenty-two patients with relapsing-remitting form of MS (RRMS) and 14 chronic-progressive (CPMS) were compared with matched controls on four tasks: a tachistoscopic verbal and non-verbal decision task, a dichotic listening test, cross tactile finger localization and motor tapping. No overall impairment was seen. The dichotic listening and lexical decision tasks were the most sensitive to MS. In addition, CPMS patients' IT was more impaired and was related to the severity of neurological impairment. The different sizes of the callosal fibers, which determine their vulnerability, may explain the heterogeneity of transfer through the Corpus Callosum. Therefore, evaluation of IT may be of value as an index of evolution in MS.

scholarly journals Long-latency reflexes for inter-effector coordination reflect a continuous state feedback controller

2018 ◽  
Vol 120 (5) ◽  
pp. 2466-2483 ◽  
Author(s):  
Frederic Crevecoeur ◽  
Isaac Kurtzer
Keyword(s):  
Feedback Control ◽  
State Feedback ◽  
Feedback Controller ◽  
State Feedback Control ◽  
Comprehensive Treatment ◽  
State Feedback Controller ◽  
Long Latency ◽  
Continuous State ◽  
Long Latency Reflex ◽  
Long Latency Reflexes

Successful performance in many everyday tasks requires compensating unexpected mechanical disturbance to our limbs and body. The long-latency reflex plays an important role in this process because it is the fastest response to integrate sensory information across several effectors, like when linking the elbow and shoulder or the arm and body. Despite the dozens of studies on inter-effector long-latency reflexes, there has not been a comprehensive treatment of how these reveal the basic control organization that sets constraints on any candidate model of neural feedback control such as optimal feedback control. We considered three contrasting ways that controllers can be organized: multiple independent controllers vs. a multiple-input multiple-output (MIMO) controller, a continuous feedback controller vs. an intermittent feedback controller, and a direct MIMO controller vs. a state feedback controller. Following a primer on control theory and review of the relevant evidence, we conclude that continuous state feedback control best describes the organization of inter-effector coordination by the long-latency reflex.

scholarly journals Long-Latency Reflexes of the Human Arm Reflect an Internal Model of Limb Dynamics

2008 ◽  
Vol 18 (6) ◽  
pp. 449-453 ◽  
Author(s):  
Isaac L. Kurtzer ◽  
J. Andrew Pruszynski ◽  
Stephen H. Scott
Keyword(s):  
Internal Model ◽  
Limb Dynamics ◽  
Long Latency ◽  
Human Arm ◽  
Long Latency Reflexes
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