scholarly journals Functional analysis of grimp, a novel gene required for mesodermal cell proliferation at an initial stage of regeneration in Enchytraeus japonensis (Enchytraeidae, Oligochaete)

2010 ◽  
Vol 54 (1) ◽  
pp. 151-160 ◽  
Author(s):  
Makoto Takeo ◽  
Chikako Yoshida-Noro ◽  
Shin Tochinai
Keyword(s):  
Functional Analysis ◽  
Cell Proliferation ◽  
Mesodermal Cell ◽  
Novel Gene ◽  
Initial Stage

EMBJ08, a novel gene promoting cell proliferation

2010 ◽  
Vol 34 (8) ◽  
pp. S50-S50
Author(s):  
Jing Li ◽  
Dongxia Hao ◽  
Weiwei Deng ◽  
Na Li ◽  
Shai Guo ◽  
...  
Keyword(s):  
Cell Proliferation ◽  
Novel Gene

scholarly journals Planarian cell number depends on blitzschnell, a novel gene family that balances cell proliferation and cell death

Development ◽  
2020 ◽  
Vol 147 (7) ◽  
pp. dev184044 ◽  
Author(s):  
Eudald Pascual-Carreras ◽  
Marta Marin-Barba ◽  
Carlos Herrera-Úbeda ◽  
Daniel Font-Martín ◽  
Kay Eckelt ◽  
...  
Keyword(s):  
Cell Proliferation ◽  
Cell Death ◽  
Gene Family ◽  
Cell Number ◽  
Novel Gene

scholarly journals The guinea pig I region. II. Functional analysis.

1977 ◽  
Vol 146 (2) ◽  
pp. 561-570 ◽  
Author(s):  
E M Shevach ◽  
M L Lundquist ◽  
A F Geczy ◽  
B D Schwartz
Keyword(s):  
Functional Analysis ◽  
Cell Proliferation ◽  
T Cell ◽  
Immune Responses ◽  
Guinea Pig ◽  
T Cell Proliferation ◽  
Ia Antigen ◽  
Ia Antigens ◽  
Region Ii ◽  
Ir Genes

We have examined whether an association exists between specific Ia antigen genes and Ir genes which are encoded within the same haplotype. Functionally monospecific sera to the Ia antigens of the guinea pig MHC were selective in their ability to inhibit antigen-specific T-cell proliferation and we were thus able to demonstrate an association between individual Ia specificities and specific Ir genes. The results of these studies in inbred animals were confirmed by examining the association of Ir genes and Ia antigens in the outbred guinea pig population. Of great interest was the observation that antisera made against cross-reactive Ia antigens of strains lacking specific Ir genes would still inhibit immune responses of strains possessing the Ir gene, if the Ir gene was associated with that Ia antigen in the responder strain.

Functional Analysis of a Retrotransposon-derived Novel Gene Expressed in the Bovine Trophoblast.

2008 ◽  
Vol 78 (Suppl_1) ◽  
pp. 214-214
Author(s):  
Yoshikage Muroi ◽  
Toshihiro Sakurai ◽  
Alan D. Ealy ◽  
James D. Godkin ◽  
Kentaro Nagaoka ◽  
...  
Keyword(s):  
Functional Analysis ◽  
Novel Gene

scholarly journals Ion Channels in Hematopoietic and Mesenchymal Stem Cells

2012 ◽  
Vol 2012 ◽  
pp. 1-9 ◽  
Author(s):  
Serena Pillozzi ◽  
Andrea Becchetti
Keyword(s):  
Stem Cells ◽  
Bone Marrow ◽  
Cell Proliferation ◽  
Ion Channels ◽  
Cell Volume ◽  
Cell Types ◽  
Cell Interaction ◽  
Integrin Receptors ◽  
Mesodermal Cell ◽  
Bone Marrow Niches

Hematopoietic stem cells (HSCs) reside in bone marrow niches and give rise to hematopoietic precursor cells (HPCs). These have more restricted lineage potential and eventually differentiate into specific blood cell types. Bone marrow also contains mesenchymal stromal cells (MSCs), which present multilineage differentiation potential toward mesodermal cell types. In bone marrow niches, stem cell interaction with the extracellular matrix is mediated by integrin receptors. Ion channels regulate cell proliferation and differentiation by controlling intracellular Ca2+, cell volume, release of growth factors, and so forth. Although little evidence is available about the ion channel roles in true HSCs, increasing information is available about HPCs and MSCs, which present a complex pattern of K+channel expression. K+channels cooperate with Ca2+and Cl−channels in regulating calcium entry and cell volume during mitosis. Other K+channels modulate the integrin-dependent interaction between leukemic progenitor cells and the niche stroma. These channels can also regulate leukemia cell interaction with MSCs, which also involves integrin receptors and affects the MSC-mediated protection from chemotherapy. Ligand-gated channels are also implicated in these processes. Nicotinic acetylcholine receptors regulate cell proliferation and migration in HSCs and MSCs and may be implicated in the harmful effects of smoking.

scholarly journals Functional analysis of the Arabidopsis thaliana SBP-box gene SPL3: a novel gene involved in the floral transition

1997 ◽  
Vol 12 (2) ◽  
pp. 367-377 ◽  
Author(s):  
Guillermo H. Cardon ◽  
Susanne Hohmann ◽  
Klaus Nettesheim ◽  
Heinz Saedler ◽  
Peter Huijser
Keyword(s):  
Functional Analysis ◽  
Arabidopsis Thaliana ◽  
Floral Transition ◽  
Novel Gene
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