Flt3 in Acute Myelogenous Leukemia: Biology, Prognosis, and Therapeutic Implications

2003 ◽  
Vol 20 (4) ◽  
pp. 311-324 ◽  
Author(s):  
Ioannis A. Voutsadakis
Keyword(s):  
Acute Myelogenous Leukemia ◽  
Myelogenous Leukemia ◽  
Therapeutic Implications ◽  
Acute Myelogenous

scholarly journals Induction of differentiation of human acute myelogenous leukemia cells: therapeutic implications

Blood ◽  
1983 ◽  
Vol 62 (4) ◽  
pp. 709-721 ◽  
Author(s):  
HP Koeffler
Keyword(s):  
Cell Differentiation ◽  
Acute Myelogenous Leukemia ◽  
Early Stage ◽  
Leukemia Cell ◽  
Leukemic Cell ◽  
Myelogenous Leukemia ◽  
Leukemia Cells ◽  
Therapeutic Implications ◽  
Stage Of Development ◽  
Acute Myelogenous

Abstract A prominent phenotypic abnormality of human acute myelogenous leukemia cells is the inability of the cells to differentiate to functional mature cells; instead, the cells are blocked at an early stage of development and remain in the proliferative pool and rapidly accumulate. Investigation of the induction of myeloid leukemic cell differentiation has made recent advances with the development of several human myelogenous leukemia cell lines. The lines provide models to study the biology of myeloid differentiation and to identify inducers of differentiation of myeloid leukemic blood cells. This review critically examines the inducers of leukemic cell differentiation and their potential therapeutic importance.

Translocation t(15;17) in acute myelogenous leukemia with atypical megakaryoblastic features: Diagnostic, clinical, and therapeutic implications

1996 ◽  
Vol 92 (1) ◽  
pp. 50-53 ◽  
Author(s):  
David L. Morgan ◽  
Dale M. Dunn ◽  
Everardo Cobos ◽  
Yi-Kong Keung ◽  
Thomas S. McConnell ◽  
...  
Keyword(s):  
Acute Myelogenous Leukemia ◽  
Myelogenous Leukemia ◽  
Therapeutic Implications ◽  
Acute Myelogenous

scholarly journals Induction of differentiation of human acute myelogenous leukemia cells: therapeutic implications

Blood ◽  
1983 ◽  
Vol 62 (4) ◽  
pp. 709-721 ◽  
Author(s):  
HP Koeffler
Keyword(s):  
Cell Differentiation ◽  
Acute Myelogenous Leukemia ◽  
Early Stage ◽  
Leukemia Cell ◽  
Leukemic Cell ◽  
Myelogenous Leukemia ◽  
Leukemia Cells ◽  
Therapeutic Implications ◽  
Stage Of Development ◽  
Acute Myelogenous

A prominent phenotypic abnormality of human acute myelogenous leukemia cells is the inability of the cells to differentiate to functional mature cells; instead, the cells are blocked at an early stage of development and remain in the proliferative pool and rapidly accumulate. Investigation of the induction of myeloid leukemic cell differentiation has made recent advances with the development of several human myelogenous leukemia cell lines. The lines provide models to study the biology of myeloid differentiation and to identify inducers of differentiation of myeloid leukemic blood cells. This review critically examines the inducers of leukemic cell differentiation and their potential therapeutic importance.

Sweet's syndrome associated with acute myelogenous leukemia.

1985 ◽  
Vol 47 (1) ◽  
pp. 3-10 ◽  
Author(s):  
Shuichi INADA ◽  
Taizo KOHNO ◽  
Iseko SAKAI ◽  
Yoriko SHIMAMOTO ◽  
Nobutaka IMAMURA ◽  
...  
Keyword(s):  
Acute Myelogenous Leukemia ◽  
Myelogenous Leukemia ◽  
Sweet’S Syndrome ◽  
Sweet's Syndrome ◽  
Acute Myelogenous
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