The Nested Variant of Urothelial Carcinoma of the Urinary Bladder: Report of Five Cases and Review of Literature

1999 ◽  
Vol 11 (2-3) ◽  
pp. 89-100 ◽  
Author(s):  
Claude Billerey ◽  
Laurent Martin ◽  
Hugues Bittard ◽  
Gérard Louis Adessi ◽  
Jean Pierre Carbillet
Keyword(s):  
Urinary Bladder ◽  
Urothelial Carcinoma ◽  
Review Of Literature ◽  
Nested Variant

scholarly journals Primary clear-cell urothelial carcinoma of urinary bladder: a not-so-clear entity with review of literature

2019 ◽  
Vol 12 (10) ◽  
pp. e231192 ◽  
Author(s):  
Lalit Kumar ◽  
Anubhav Narwal ◽  
Manoj Kumar ◽  
Seema Kaushal
Keyword(s):  
Urinary Bladder ◽  
Urothelial Carcinoma ◽  
Urothelial Cancer ◽  
Clear Cell ◽  
Muscularis Propria ◽  
Urinary Bladder Cancer ◽  
Review Of Literature ◽  
Unusual Variant ◽  
Urothelial Tumours

Primary clear-cell urothelial carcinoma (CCUC) is an uncommon type of urothelial cancer with only 16 cases reported in published literature. Due to the rarity of the tumour, its clinical and prognostic values have not been clearly understood. We present one such rare clinical diagnosis in a 60-year- old man who underwent radical cystectomy (RC) with ileal conduit for urinary bladder cancer. Histopathology showed features of high-grade CCUC infiltrating the muscularis propria. Immunohistochemistry revealed diffuse immunopositivity of pan cytokeratin (CK), GATA3, P40, CK7 but was immunonegative for CD10 and vimentin. Our patient expired 4 months after diagnosis. CCUC has recently been included in the WHO 2016 classification of urothelial tumours. Most of the patients present with poor prognosis. Accurate diagnosis and recognition of this unusual variant are essential for better patient management and prognosis. Early RC seems to be the preferred way of management.

Pure form of a nested variant of urothelial carcinoma of the urinary bladder—A case report—

2015 ◽  
Vol 54 (6) ◽  
pp. 377-382
Author(s):  
Tomonori KOZAKAI ◽  
Keiji IIZUKA ◽  
Kazuyo NISHIZAWA ◽  
Akiko ISHIDA ◽  
Hiroyoshi OTA
Keyword(s):  
Case Report ◽  
Urinary Bladder ◽  
Urothelial Carcinoma ◽  
Pure Form ◽  
Nested Variant

MRI features of the nested variant of urothelial carcinoma of the urinary bladder: report of four cases

2020 ◽  
Vol 45 (7) ◽  
pp. 2279-2285
Author(s):  
Kaori Yamada ◽  
Yasuteru Sasakura ◽  
Sachimi Yamada ◽  
Hitomi Nagano ◽  
Koshi Terayama ◽  
...  
Keyword(s):  
Urinary Bladder ◽  
Urothelial Carcinoma ◽  
Mri Features ◽  
Nested Variant

scholarly journals A case of nested variant of urothelial carcinoma of the urinary bladder

2012 ◽  
Vol 51 (4) ◽  
pp. 295-298
Author(s):  
Akiko KAGOTANI ◽  
Mitsuaki ISHIDA ◽  
Keiko YOSHIDA ◽  
Muneo IWAI ◽  
Yoshimitsu MIYAHIRA ◽  
...  
Keyword(s):  
Urinary Bladder ◽  
Urothelial Carcinoma ◽  
Nested Variant

Pseudocarcinomatous Hyperplasia of the Urinary Bladder

2014 ◽  
Vol 138 (10) ◽  
pp. 1268-1271 ◽  
Author(s):  
Angela Wu
Keyword(s):  
Radiation Therapy ◽  
Urinary Bladder ◽  
Urothelial Carcinoma ◽  
Stromal Cells ◽  
Background Radiation ◽  
Differential Diagnoses ◽  
Ischemic Insult ◽  
Background Therapy ◽  
Nested Variant ◽  
Study Case

We review the morphology and differential diagnoses of pseudocarcinomatous hyperplasia of the bladder, using a study case to illustrate the discussion. Pseudocarcinomatous hyperplasia is a rare, reactive response to an ischemic insult, classically to radiation therapy, and consists of proliferative, pseudoinfiltrative urothelial nests within the stroma. The presence of background radiation therapy–related changes, such as numerous dilated thrombosed vessels, reactive-appearing endothelial and stromal cells, edema, and hemorrhage, can provide clues to the diagnosis. The main differential diagnoses include invasive urothelial carcinoma and the nested variant of urothelial carcinoma; morphologic features, such as the presence or absence of background therapy-related changes and the architecture and the cytologic atypia of the nests, can help distinguish between pseudocarcinomatous hyperplasia and urothelial carcinoma.

EMP2 induces cytostasis and apoptosis via the TGFβ/SMAD/SP1 axis and recruitment of P2RX7 in urinary bladder urothelial carcinoma

2021 ◽  
Author(s):  
Chien-Feng Li ◽  
Ti-Chun Chan ◽  
Cheng-Tang Pan ◽  
Pichpisith Pierre Vejvisithsakul ◽  
Jia-Chen Lai ◽  
...  
Keyword(s):  
Urinary Bladder ◽  
Urothelial Carcinoma ◽  
Bladder Urothelial Carcinoma
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