Ability of Peripheral Bone Assessments to Predict Areal Bone Mineral Density at Hip in Community-Dwelling Elderly Men

2002 ◽  
Vol 5 (3) ◽  
pp. 219-228 ◽  
Author(s):  
Stefan Goemaere ◽  
Hans Zmierczak ◽  
Inge Van Pottelbergh ◽  
Jean Marc Kaufman
Keyword(s):  
Bone Mineral Density ◽  
Bone Mineral ◽  
Community Dwelling ◽  
Areal Bone Mineral Density ◽  
Mineral Density ◽  
Elderly Men ◽  
Peripheral Bone

scholarly journals Mandibular and Palatal Tori, Bone Mineral Density, and Salivary Cortisol in Community-Dwelling Elderly Men and Women

2001 ◽  
Vol 56 (11) ◽  
pp. M731-M735 ◽  
Author(s):  
J. Hjertstedt ◽  
E. A. Burns ◽  
R. Fleming ◽  
H. Raff ◽  
I. Rudman ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Bone Mineral ◽  
Salivary Cortisol ◽  
Community Dwelling ◽  
Mineral Density ◽  
Elderly Men ◽  
Men And Women

scholarly journals Bioavailable Estradiol and an Aromatase Gene Polymorphism Are Determinants of Bone Mineral Density Changes in Men over 70 Years of Age

2003 ◽  
Vol 88 (7) ◽  
pp. 3075-3081 ◽  
Author(s):  
I. Van Pottelbergh ◽  
S. Goemaere ◽  
J. M. Kaufman
Keyword(s):  
Bone Mineral Density ◽  
Bone Loss ◽  
Bone Mineral ◽  
Community Dwelling ◽  
Repeat Length ◽  
Distal Forearm ◽  
Mineral Density ◽  
Elderly Men ◽  
Cyp19 Gene ◽  
Fracture History

The question of whether and to what extent the sex steroid deficiency in elderly men contributes to the pathogenesis of bone loss has not been fully explored. The aim of the present study was to assess the association of serum bioavailable (Bio) estradiol (E2) with the evolution of bone mineral density (BMD) in 214 community-dwelling men aged 71–86 yr as well as the possible modulation of estrogen effects by a tetranucleotide (TTTA)n-repeat polymorphism of the CYP19 gene, which encodes the aromatase enzyme that converts androgens into estrogens. BMD was measured at yearly intervals over a period of 4 yr using dual x-ray absorptiometry. Fasting blood was analyzed at baseline for testosterone (T), E2, and SHBG; the respective bioavailable fractions, BioT and BioE2, were calculated. Serum BioE2 was associated with baseline BMD at different assessed skeletal sites, with correlation coefficients ranging between 0.23 and 0.37 (P < 0.001). Estimated annual percentage change of BMD (%BMD) was −0.39% [95% confidence index (CI), −0.56, −0.22] at the total hip, −0.04% (95% CI, −0.29, 0.21) at the femoral neck, and −0.37% (95% CI, −0.45, −0.29) at the total distal forearm. Higher circulating BioE2 levels were associated with less bone loss at the forearm and the hip (P < 0.05). The CYP19 gene (TTTA)n-repeat length (determined by fragment analysis) was not associated with baseline BMD in the total group of elderly men. However, a significant association was observed between the CYP19 genotype and BMD change at the distal forearm; the highest bone loss was observed in subjects homozygotic for the shortest observed allele length of (TTTA)7-repeats (P < 0.02). The CYP19 (TTTA)n-repeat length was not associated with either baseline BioE2 or the BioT/BioE2 ratio. In multiple linear regression models, the CYP19 genotype and serum BioE2 were determinants of %BMD change at the forearm (P < 0.05). No significant contribution of BioT to %BMD change was evident. As to fracture risk, the allele containing the shortest (TTTA)n-repeat length was more represented not only in elderly men with a positive personal fracture history (Pearson’s χ2 test = 4.03; df = 1; P = 0.05) but also in study subjects with a positive fracture history in their first-degree relatives (Pearson’s χ2 test = 6.48; df = 1; P = 0.01). In conclusion, the results of this prospective observational study support the view that BioE2 is a determinant of bone density changes in elderly men and, furthermore, provide an indication that the aromatase enzyme may exert a direct modulatory action on bone metabolism at the tissue level in elderly men.

High doses of vitamin C plus E reduce strength training-induced improvements in areal bone mineral density in elderly men

2017 ◽  
Vol 117 (6) ◽  
pp. 1073-1084 ◽  
Author(s):  
Astrid Kamilla Stunes ◽  
Unni Syversen ◽  
Sveinung Berntsen ◽  
Gøran Paulsen ◽  
Tonje H. Stea ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Vitamin C ◽  
Strength Training ◽  
Bone Mineral ◽  
Areal Bone Mineral Density ◽  
Mineral Density ◽  
Elderly Men ◽  
High Doses

Fracture risk among men, in relation to osteopenia and osteoporosis defined by areal bone mineral density

2013 ◽  
Author(s):  
Julie Pasco ◽  
Stephen Lane ◽  
Sharon Brennan ◽  
Elizabeth Timney ◽  
Gosia Bucki-Smith ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Fracture Risk ◽  
Bone Mineral ◽  
Areal Bone Mineral Density ◽  
Mineral Density

Evaluation of vertebral volumetric vs. areal bone mineral density during growth

Bone ◽  
1997 ◽  
Vol 20 (6) ◽  
pp. 553-556 ◽  
Author(s):  
S.M. Ott ◽  
M. O'Hanlan ◽  
E.W. Lipkin ◽  
L. Newell-Morris
Keyword(s):  
Bone Mineral Density ◽  
Bone Mineral ◽  
Areal Bone Mineral Density ◽  
Mineral Density

scholarly journals Relationship of age to bone microstructure independent of areal bone mineral density

2012 ◽  
Vol 27 (3) ◽  
pp. 637-644 ◽  
Author(s):  
Kristy M Nicks ◽  
Shreyasee Amin ◽  
Elizabeth J Atkinson ◽  
B Lawrence Riggs ◽  
L Joseph Melton ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Bone Mineral ◽  
Bone Microstructure ◽  
Areal Bone Mineral Density ◽  
Mineral Density ◽  
Relationship Of

Does Bone Mineral Density and Knowledge Influence Health-Related Behaviors of Elderly Men at Risk for Osteoporosis?

2003 ◽  
Vol 6 (4) ◽  
pp. 323-329 ◽  
Author(s):  
Avni Patel ◽  
Penelope S. Coates ◽  
Joel B. Nelson ◽  
Donald L. Trump ◽  
Neil M. Resnick ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
At Risk ◽  
Bone Mineral ◽  
Mineral Density ◽  
Elderly Men ◽  
Health Related Behaviors ◽  
Health Related
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