The 70-kDa Peroxisomal Membrane Protein (PMP70), an ATP-Binding Cassette Transporter

2000 ◽  
Vol 32 (1-3) ◽  
pp. 131-138 ◽  
Author(s):  
Tsuneo Imanaka ◽  
Kazutoshi Aihara ◽  
Yasuyuki Suzuki ◽  
Sadaki Yokota ◽  
Takashi Osumi
Keyword(s):  
Membrane Protein ◽  
Atp Binding ◽  
Peroxisomal Membrane ◽  
Peroxisomal Membrane Protein ◽  
Atp Binding Cassette Transporter ◽  
Atp Binding Cassette

scholarly journals Characterization of the 70-kDa Peroxisomal Membrane Protein, an ATP Binding Cassette Transporter

1999 ◽  
Vol 274 (17) ◽  
pp. 11968-11976 ◽  
Author(s):  
Tsuneo Imanaka ◽  
Kazutoshi Aihara ◽  
Tatsuya Takano ◽  
Atsushi Yamashita ◽  
Ryuichiro Sato ◽  
...  
Keyword(s):  
Membrane Protein ◽  
Atp Binding ◽  
Peroxisomal Membrane ◽  
Peroxisomal Membrane Protein ◽  
Atp Binding Cassette Transporter ◽  
Atp Binding Cassette

Molecular insights into type I secretion systems

2013 ◽  
Vol 394 (11) ◽  
pp. 1371-1384 ◽  
Author(s):  
Michael H.H. Lenders ◽  
Sven Reimann ◽  
Sander H. J. Smits ◽  
Lutz Schmitt
Keyword(s):  
Membrane Protein ◽  
Outer Membrane ◽  
Outer Membrane Protein ◽  
Atp Binding ◽  
Type I ◽  
Secretion Systems ◽  
Inner Membrane ◽  
Small Proteins ◽  
Atp Binding Cassette Transporter ◽  
Atp Binding Cassette

Abstract Type 1 secretion systems are one of the main machineries in Gram-negative bacteria involved in the secretion of a wide range of substrates from the cytoplasm across the inner and outer membrane in one step to the extracellular space. The range of substrates varies from small proteins up to large surface layer proteins of about 900 kDa. Most of the substrates have a non-cleavable C-terminal secretion signal and so-called GG repeats that are able to bind calcium ions. The translocator complex is composed of a trimeric outer membrane protein that provides a pore in the outer membrane. A multimeric membrane fusion protein spans the periplasm and forms a continuous channel connecting the outer membrane protein with a dimeric ATP-binding cassette transporter in the inner membrane. The ATP-binding cassette-transporter is thought to form a channel through the inner membrane and energizes the transport process. This review will provide a detailed view of the components of the translocator and will summarize structural as well as functional data.

Sign in / Sign up

Export Citation Format

Share Document