Computer Simulation for Effect of Pr(III) on Ca(II) Speciation in Human Interstitial Fluid

2003 ◽  
Vol 94 (2) ◽  
pp. 131-140 ◽  
Author(s):  
Haiyuan Zhang ◽  
Xing Lu ◽  
Jinping Wang ◽  
Kuiyue Yang ◽  
Chunji Niu
Keyword(s):  
Computer Simulation ◽  
Interstitial Fluid ◽  
Human Interstitial Fluid

Computer simulation of Gd(III) speciation in human interstitial fluid

BioMetals ◽  
2004 ◽  
Vol 17 (6) ◽  
pp. 599-603 ◽  
Author(s):  
Jinping Wang ◽  
Haiyuan Zhang ◽  
Kuiyue Yang ◽  
Chunji Niu
Keyword(s):  
Computer Simulation ◽  
Interstitial Fluid ◽  
Human Interstitial Fluid

Computer Simulation for Effect of Pr(III) on Ca(II) Speciation in Human Interstitial Fluid

2003 ◽  
Vol 95 (1) ◽  
pp. 39-48
Author(s):  
Haiyuan Zhang ◽  
Xing Lu ◽  
Jinping Wang ◽  
Kuiyue Yang ◽  
Chunji Niu ◽  
...  
Keyword(s):  
Computer Simulation ◽  
Interstitial Fluid ◽  
Human Interstitial Fluid

Computer simulation of Pr(III) speciation in human interstitial fluid

2004 ◽  
Vol 16 (4) ◽  
pp. 153-158 ◽  
Author(s):  
Haiyuan Zhang ◽  
Xin Lu ◽  
Jinping Wang ◽  
Kuiyue Yang ◽  
Chunji Niu ◽  
...  
Keyword(s):  
Computer Simulation ◽  
Interstitial Fluid ◽  
Human Interstitial Fluid

scholarly journals Metabolomics of Interstitial Fluid, Plasma and Urine in Patients with Arterial Hypertension: New Insights into the Underlying Mechanisms

Diagnostics ◽  
2020 ◽  
Vol 10 (11) ◽  
pp. 936
Author(s):  
Angelika Chachaj ◽  
Rafał Matkowski ◽  
Gerhard Gröbner ◽  
Andrzej Szuba ◽  
Ilona Dudka
Keyword(s):  
Arterial Hypertension ◽  
Interstitial Fluid ◽  
Ethical Issues ◽  
Proton Nuclear Magnetic Resonance ◽  
Axillary Lymph ◽  
Oncological Patients ◽  
Simultaneous Evaluation ◽  
Human Interstitial Fluid ◽  
Clear Differentiation ◽  
Underlying Mechanisms

There is growing evidence that lymphatic system plays a pivotal role in the pathogenesis of hypertension. Here, for the first time, the metabolome of interstitial fluid is analyzed in patients with arterial hypertension. Due to ethical issues to obtain human interstitial fluid samples, this study included only oncological patients after axillary lymph node dissection (ALND). These patients were matched into hypertensive (n = 29) and normotensive (n = 35) groups with similar oncological status. Simultaneous evaluation of interstitial fluid, plasma, and urine was obtained by combining high-resolution proton nuclear magnetic resonance (1H NMR) spectroscopy with chemometric analysis. Orthogonal partial least squares discriminant analysis (OPLS-DA) provided a clear differentiation between the hypertension and normotensive group, with the discrimination visible in each biofluid. In interstitial fluid nine potential metabolomic biomarkers for hypertension could be identified (creatinine, proline, pyroglutamine, glycine, alanine, 1-methylhistidine, the lysyl group of albumin, threonine, lipids), seven distinct markers in plasma (creatinine, mannose, isobutyrate, glycine, alanine, lactate, acetate, ornithine), and seven respectively in urine (methylmalonate, citrulline, phenylacetylglycine, fumarate, citrate, 1-methylnicotinamide, trans-aconitate). Biomarkers in plasma and urine allowed for the identification of specific biochemical pathways involved in hypertension, as previously suggested. Analysis of the interstitial fluid metabolome provided additional biomarkers compared to plasma or urine. Those biomarkers reflected primarily alterations in the metabolism of lipids and amino acids, and indicated increased levels of oxidative stress/inflammation in patients with hypertension.

Effect of Praseodymium(III) on Zinc(II) Species in Human Interstitial Fluid

2005 ◽  
Vol 107 (2) ◽  
pp. 101-112
Author(s):  
Haiyuan Zhang ◽  
Jinping Wang ◽  
Xin Lu ◽  
Kuiyue Yang ◽  
Chunji Niu
Keyword(s):  
Interstitial Fluid ◽  
Human Interstitial Fluid

A Method for Measurement of Antibiotics in Human Interstitial Fluid

1972 ◽  
Vol 126 (5) ◽  
pp. 492-497 ◽  
Author(s):  
J. S. Tan ◽  
A. Trott ◽  
J. P. Phair ◽  
C. Watanakunakorn
Keyword(s):  
Interstitial Fluid ◽  
Human Interstitial Fluid

Interstitial fluid oncotic pressures in rabbit subcutaneous tissue

1976 ◽  
Vol 231 (3) ◽  
pp. 888-891 ◽  
Author(s):  
DD Stromberg ◽  
CA Wiederhielm
Keyword(s):  
Computer Simulation ◽  
Plasma Proteins ◽  
Interstitial Fluid ◽  
Subcutaneous Tissue ◽  
The Body ◽  
Computer Simulation Study ◽  
Rabbit Skin ◽  
Small Pore ◽  
Subcutaneous Tissues ◽  
Capillary Fluid

Interstitial fluid oncotic pressures in rabbit subcutaneous tissues were measured by chronically implanted membrane osmometers. Pairs of osmometers were used, one using a membrane permeable and one impermeable to plasma proteins. Measurements from the small-pore membranes averaged 10.2 mmHg while pressures measured from the large-pore membrane osmometers averaged -1.2 mmHg, indicating that the measured pressures were osmotic rather than hydrostatic in nature. These values are in agreement with previously published values from this laboratory on oncotic pressures of excised rabbit skin and with a computer-simulation study of capillary fluid balance. The oncotic pressures described in this study are of the s-me general magnitude as those of lymph from most organs in the body.

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