Zinc Uptake by Human Placental Microvillous Membrane Vesicles : Effects of Gestational Age and Maternal Serum Zinc Levels

2000 ◽  
Vol 73 (2) ◽  
pp. 127-138 ◽  
Author(s):  
Carmina L. Vargas Zapata ◽  
Nadia M. F. Trugo ◽  
Carmen M. Donangelo
Keyword(s):  
Gestational Age ◽  
Serum Zinc ◽  
Membrane Vesicles ◽  
Maternal Serum ◽  
Zinc Uptake ◽  
Zinc Levels ◽  
Microvillous Membrane Vesicles ◽  
Serum Zinc Levels

scholarly journals SMALL BABIES

2005 ◽  
Vol 12 (03) ◽  
pp. 336-339
Author(s):  
MUHAMMAD ASHRAF ◽  
Zamir Ahmad ◽  
MUHAMMAD NASARULLAH KHAN ◽  
Tariq Ferroz Khawaja ◽  
MUHAMMAD AYUB KHAN ◽  
...  
Keyword(s):  
Dna Polymerase ◽  
Gestational Age ◽  
Serum Zinc ◽  
Maternal Serum ◽  
Maternal Complications ◽  
Metallic Component ◽  
Zinc Levels ◽  
Relationship Of ◽  
The Relationship ◽  
Serum Zinc Levels

Zinc is an essential trace mineral. It is considered a growth factor as it isthe metallic component of enzymes DNA polymerase, DNA dependent RNA polymerase and thymidine kinase.Objective: To find out the relationship of maternal serum zinc levels with birth weight of the babies. Period: January1989 to May, 1991. Setting: Lady Wellingdon Hospital Lahore, King Edward College, Lahore and MetallurgyDepartment PCSIR Laboratories, Lahore. Design: Prospective study Patients & methods: Among the 216 registeredpregnant women 46 subjects had no feto-maternal complications during pregnancy and they delivered babies havingbirth weight adequate for Gestational Age (AGA). Thirteen women gave birth to babies Small for Gestational Age(SGA). Blood samples were taken at the end of each trimester and serum zinc was measured by atomic absorptionspectrophotometer. Results: Serum zinc levels were significantly low (P<0.001) throughout pregnancy in women givingbirth to SGA babies. Conclusion: Serum zinc levels throughout the course of pregnancy are associated with intrauterinegrowth of the babies.b

A Prospective Survey of Serial Maternal Serum Zinc Levels and Pregnancy Outcome

1988 ◽  
Vol 7 (3) ◽  
pp. 430-433 ◽  
Author(s):  
Akimasa Higashi ◽  
Akiko Tajiri ◽  
Makoto Matsukura ◽  
Ichiro Matsuda
Keyword(s):  
Pregnancy Outcome ◽  
Serum Zinc ◽  
Maternal Serum ◽  
Prospective Survey ◽  
Zinc Levels ◽  
Serum Zinc Levels

scholarly journals Comparison of maternal serum and neonatal cord blood levels of zinc in relation to birth weight and period of gestation

2021 ◽  
Vol 8 (8) ◽  
pp. 1349
Author(s):  
Shabbeer Ahmed ◽  
Avula Kanthi Sagar
Keyword(s):  
Birth Weight ◽  
Cord Blood ◽  
Zinc Deficiency ◽  
Serum Zinc ◽  
Maternal Serum ◽  
Blood Levels ◽  
P Value ◽  
Zinc Levels ◽  
Blood Zinc ◽  
Serum Zinc Levels

Background: Women are at increased risk of zinc deficiency during pregnancy because of high fetal requirements for zinc. Severe maternal zinc deficiency has been associated with poor fetal growth, spontaneous abortion and congenital malformations (i.e., anencephaly), whereas milder forms of zinc deficiency have been associated with low birth weight (LBW), intrauterine growth retardation, and preterm delivery. However, the research relating maternal zinc status and birth weight has not produced consistent results. This study has been undertaken to confirm the association between maternal serum zinc concentration and birth weight and period of gestation in setting like India.Methods: A total of 100 new-borns were included and divided into two groups, the ‘study group’ had babies with birth weight <2.5 kg and control group’ with babies >2.5 kg birth weight. Cord blood from the new-borns and serum samples of mothers were collected and the zinc levels were measured.Results: The correlation of cord blood and the maternal serum zinc levels were assessed in relation to birth weight and the gestational age. The results were compared between the two groups. The difference in values between the two groups was statistically significant, maternal serum zinc levels and birth weight (84.78±21.62 vs 66.04±18.66) (‘P’ value 0.04), cord blood zinc levels and birth weight (98.44±22.59 vs 79.78±19.54) (‘P’ value <0.001). The maternal serum and cord blood zinc was compared between the preterm and term; the results were statistically significant.Conclusions: The maternal and cord blood levels of zinc are correlated well with the birth weight and the gestational age at delivery. Supplementation of zinc during gestation might help reduce the incidence of IUGR and the risk of prematurity.

A prospective study of serial maternal serum zinc levels and pregnancy outcome

1982 ◽  
Vol 7 (1) ◽  
pp. 59-69 ◽  
Author(s):  
A.J. McMichael ◽  
I.E. Dreosti ◽  
G.T. Gibson ◽  
J.M. Hartshorne ◽  
R.A. Buckley ◽  
...  
Keyword(s):  
Prospective Study ◽  
Pregnancy Outcome ◽  
Serum Zinc ◽  
Maternal Serum ◽  
Zinc Levels ◽  
A Prospective Study ◽  
Serum Zinc Levels

scholarly journals Zinc Serum Maternal Levels as a Risk Factor for Preeclampsia

2021 ◽  
Vol 5 (4) ◽  
pp. 1110-1118
Author(s):  
Abarham Martadiansyah ◽  
Peby Maulina ◽  
Putri Mirani ◽  
Tia Kaprianti ◽  
Theodorus
Keyword(s):  
Pregnant Women ◽  
Dietary Habits ◽  
Serum Zinc ◽  
Zinc Level ◽  
Maternal Serum ◽  
Control Group ◽  
Case Group ◽  
Serum Zinc Level ◽  
Zinc Levels ◽  
Serum Zinc Levels

Background. Preeclampsia is defined as gestational hypertension and proteinuria which can be measured by the elevation of liver transaminases to twice normal concentration, and the symptoms of increased intracranial pressure such as dizziness, blurred vision, and seizures. Zinc is an essential mineral for many biological functions and one of the trace elements that is directly involved in the oxidative/antioxidant balance, a pathogenesis process in preeclampsia that is highly dependent on dietary habits and supplements. This study was aimed to assess the association between serum zinc level with preeclampsia (PE). Methods: This observational, case-control study was performed on 90 women with singleton pregnancies at 28 to 42 weeks of gestation which were referred to the Department of Obstetrics and Gynecology, Dr. Mohammad Hoesin General Hospital, Palembang, between August 2020 to November 2020. 30 pregnant women with PE were selected as cases and 60 healthy pregnant women were selected as controls. Maternal serum zinc samples were collected. The collected data were entered into the master table. Tabulation, coding, and statistical data analysis were performed using SPSS version 20.0 for Windows. Results: The mean serum zinc levels in the case group and control group were 43,90 ± 15,79 µg/dL (ranged from 15 to 86 µg/dL) and 48,77 ± 10,54 µg/dL (ranged from 22 to 83 µg/dL), respectively. A value of serum zinc levels with the best sensitivity and specificity was 45,5 µg/dL. Conclusion: There was a significant association between maternal serum zinc level with PE. The risk of PE was 3,2 times higher in pregnant women with serum zinc levels of ≤45,5 mcg/dL compared to pregnant women with serum zinc levels of >45,5 mcg/dL. In this case it is necessary to supplement zinc earlier in pregnancy to reduce the risk of preeclampsia.

The relationship between maternal serum zinc levels during pregnancy and birthweight

1991 ◽  
Vol 25 (2) ◽  
pp. 75-85 ◽  
Author(s):  
Yasmin H. Neggers ◽  
Gary R. Cutter ◽  
Jose O. Alvarez ◽  
Robert L. Goldenberg ◽  
Ronald Acton ◽  
...  
Keyword(s):  
Serum Zinc ◽  
Maternal Serum ◽  
Zinc Levels ◽  
The Relationship ◽  
Serum Zinc Levels

scholarly journals Linear growth patterns in small for gestational age and preterm infants after zinc supplementation

2015 ◽  
Vol 55 (1) ◽  
pp. 23
Author(s):  
Caecilia Nancy Setiawan ◽  
Gatot Irawan Sarosa ◽  
Mexitalia Setiawati
Keyword(s):  
Gestational Age ◽  
Small For Gestational Age ◽  
Linear Growth ◽  
Zinc Supplementation ◽  
Serum Zinc ◽  
Growth Patterns ◽  
Median Percentage ◽  
The Third ◽  
Zinc Levels ◽  
Serum Zinc Levels

Background Low birth weight (LBW) infants are at risk for growth disturbances due to intrauterine zinc deficiency. Zinc supplementation is expected to improve the linear growth of LBW babies. Objective To assess the effect of zinc supplementation on linear growth in preterm and small for gestational age (SGA) infants. Methods This quasi-experimental study had a pre- and post-test design. Subjects were LBW infants hospitalized in Kariadi Hospital during March-December 2011, consisted of SGA and preterm neonates. All subjects were given 5 mg of zinc syrup daily for 3 months. Subjects’ head circumference, weight, and length were measured monthly. Serum zinc levels were measured before and after supplementation. Data were analyzed with Chi-square test, independent T-test, and general linear model repeated measure. Results A total of 61 subjects were enrolled consisted of 31 preterm and 30 SGA neonates. Mean serum zinc levels in the preterm group were 168.2 (SD 54.5) μg/dL pre-supplementation and 163.6 (SD 50.7) μg/dL post-supplementation (P=0.049), while mean serum zinc levels in the SGA group were 174.8 (SD 46.6) μg/dL pre-supplementation and 167.4 (SD 49.4) μg/dL post-supplementation (P=0.271). Median percentage preterm weight and length increased from 87.3 to 102.4% in the third month (P<0.001) and from 95.8 to 103.9% in the third month (P<0.001), respectively. Median percentage SGA weight and length increased from 73.5 to 98.3% in the third month (P<0.001) and from 94.5 to 102.2% in the third month (P<0.001), respectively. Conclusion Both, the preterm and SGA infants exhibit catch-up growth after three months of zinc supplementation. [

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