Respiratory Muscle Strength and Control of Ventilation in Patients with Neuromuscular Disease

CHEST Journal ◽  
1991 ◽  
Vol 99 (2) ◽  
pp. 330-338 ◽  
Author(s):  
Ahmet Baydur
2019 ◽  
Vol 45 (6) ◽  
Author(s):  
Rejane Barreto dos Santos ◽  
Anderson Santos Fraga ◽  
Maria das Graças Wanderley de Sales Coriolano ◽  
Bruna Ferreira Tiburtino ◽  
Otávio Gomes Lins ◽  
...  

ABSTRACT Objective: To investigate parameters of lung function and respiratory muscle strength in different stages of Parkinson’s disease (PD), as well as to determine their correlation with motor function and quality of life. Methods: This was a cross-sectional study conducted at a referral center for PD in the city of Recife, Brazil. Respiratory muscle strength and lung function, as well as their relationship with motor function and quality of life, were evaluated in patients with PD, stratified by the level of severity, and were compared with the data obtained for a control group. After confirming the normality of data distribution, we performed one-way ANOVA with a post hoc t-test. Results: The sample comprised 66 individuals, in two groups: PD (n = 49) and control (n = 17). All of the parameters investigated showed inverse correlations with PD severity, and there were significant differences among the levels of severity, as well as between the PD and control groups, in terms of the MIP, MEP, FVC, FEV1, and FEF25-75%. The lung function parameters also showed moderate to weak inverse correlations with bradykinesia and rigidity. On a quality of life questionnaire, the total score and mobility domain score both presented a moderate inverse correlation with FVC, FEV1, PEF, and MEP. Conclusions: Respiratory muscle strength and some lung function parameters are impaired from the early stages of PD onward, bradykinesia and rigidity being the cardinal signs that correlate most strongly with impairment of those parameters. Such alterations negatively affect the quality of life of patients with PD.


2020 ◽  
Vol 79 (Suppl 1) ◽  
pp. 912.1-912
Author(s):  
S. Baglan Yentur ◽  
D. C. Saraç ◽  
F. Sarİ ◽  
N. G. Tore ◽  
H. Satiş ◽  
...  

Background:Ankylosing Spondylitis (AS) is a chronic, inflammatory rheumatic disease that effects primarily axial spine. Reduction in flexibility and mobility is important factors that can cause muscle weakness, impairment quality of life, reduction of exercise tolerance and pulmonary capacity with the progression of AS.Objectives:The purpose of this study was to investigate the effects of pilates exercises on mobility, quality of life and respiratory muscle strength in patients with AS.Methods:Forty patients with AS were randomly divided into two groups as pilates group and control group. Pilates group was performed pilates exercises and control group performed conventional exercises at home for 8 weeks, 3 days a week. Main outcome measures were maximal inspiratory pressure (MIP), maximal expiratory pressure (MEP). Secondary outcome measures were Forced Vital Capacity (FVC), Forced expiratory volume in one second/Forced Vital Capacity (FEV1/FVC), chest expansion, Bath Ankylosing Spondylitis Disease Activity Index (BASDAI), Bath Ankylosing Spondylitis Metrology Index (BASMI) and Ankylosing Spondylitis Quality of Life Questionnaire (ASQoL), 6 minutes walk test (6MWT). All participants were assessed by a blind assessor before and after the study.Results:Thirty-six AS patients (n=19 in the pilates group, n= 17 in the control group) completed the study. In the pilates group, respiratory muscle strength, FEV1/FVC, chest expansion, BASDAI, BASMI, ASQoL and 6MWT showed significant improvements at 8thweek (p<0.05), while inspiratory muscle strength, FEV1/FVC, chest expansion and 6MWT showed significant improvements in the control group at 8thweek compared to baseline (p<0.05). Although the pilates group had better outcomes for all parameters compared to the control group, significant differences were only observed in MIP and MEP.Conclusion:Pilates method is an effective method for improving respiratory parameters, spinal mobility, disease activity and quality of life. Additionally, pilates training is found to be superior compared to conventional exercise training in improving respiratory muscle strength.References:[1] Sampaio-Barros PD, Cerqueira EMF, Rezende SM, Maeda L, Conde RA, Zanardi VA et al. Pulmonary involvement in ankylosing spondylitis. Clinical rheumatology. 2007;26(2):225-30.[2] Ozdem OY, Inanici F, Hascelik Z. Reduced vital capacity leads to exercise intolerance in patients with ankylosing spondylitis. European journal of physical and rehabilitation medicine. 2011;47(3):391-7.[3] Altan L, Korkmaz N, Dizdar M, Yurtkuran M. Effect of Pilates training on people with ankylosing spondylitis. Rheumatology international. 2012;32(7):2093-9.Disclosure of Interests:None declared


Gerontology ◽  
2021 ◽  
pp. 1-10
Author(s):  
Tatsuma Okazaki ◽  
Yoshimi Suzukamo ◽  
Midori Miyatake ◽  
Riyo Komatsu ◽  
Masahiro Yaekashiwa ◽  
...  

Introduction: The respiratory muscle strength regulates the effectiveness of coughing, which clears the airways and protects people from pneumonia. Sarcopenia is an aging-related loss of muscle mass and function, the worsening of which is associated with malnutrition. The loss of respiratory and swallowing muscle strength occurs with aging, but its effect on pneumonia is unclear. This study aimed to determine the risks of respiratory muscle weakness on the onset and relapse of pneumonia in older people in conjunction with other muscle-related factors such as malnutrition. Methods: We conducted a longitudinal study with 47 pneumonia inpatients and 35 non-pneumonia controls aged 70 years and older. We evaluated the strength of respiratory and swallowing muscles, muscle mass, and malnutrition (assessed by serum albumin levels and somatic fat) during admission and confirmed pneumonia relapse within 6 months. The maximal inspiratory and expiratory pressures determined the respiratory muscle strength. Swallowing muscle strength was evaluated by tongue pressure. Bioelectrical impedance analysis was used to evaluate the muscle and fat mass. Results: The respiratory muscle strength, body trunk muscle mass, serum albumin level, somatic fat mass, and tongue pressure were significantly lower in pneumonia patients than in controls. Risk factors for the onset of pneumonia were low inspiratory respiratory muscle strength (odds ratio [OR], 6.85; 95% confidence interval [CI], 1.56–30.11), low body trunk muscle mass divided by height2 (OR, 6.86; 95% CI, 1.49–31.65), and low serum albumin level (OR, 5.46; 95% CI, 1.51–19.79). For the relapse of pneumonia, low somatic fat mass divided by height2 was a risk factor (OR, 20.10; 95% CI, 2.10–192.42). Discussion/Conclusions: Respiratory muscle weakness, lower body trunk muscle mass, and malnutrition were risk factors for the onset of pneumonia in older people. For the relapse of pneumonia, malnutrition was a risk factor.


2016 ◽  
Vol 22 (3) ◽  
pp. 124-132 ◽  
Author(s):  
Raphael N. Pereira ◽  
Marcos Fabio R. Abreu ◽  
Camila B. Gonçalves ◽  
Wilson Flávio S. Corrêa ◽  
Daniel R. Mizuhira ◽  
...  

1987 ◽  
Vol 7 (6) ◽  
pp. 466-469 ◽  
Author(s):  
P. G&oacute;mez-Fern&aacute;ndez ◽  
Sanchez Agudo ◽  
J.L. Miguel ◽  
M. Almaraz ◽  
Vila Dupla

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