Inappropriate Use of Intravenous PPI for Stress Ulcer Prophylaxis in an Inner-city Community Hospital

CHEST Journal ◽  
2010 ◽  
Vol 138 (4) ◽  
pp. 269A
Author(s):  
Muhammad K. Perwaiz ◽  
Francis Schmidt ◽  
Fadi Hammoudeh
Author(s):  
Dhani Wijaya ◽  
Elfri Padolo ◽  
Chrismawan Ardianto ◽  
Fendy Matulatan ◽  
Chris Alderman ◽  
...  

AbstractBackgroundStress ulcer is a superficial and asymptomatic lesion and causes bleeding. As many as 50% of death cases are reported as the result of stress ulcer bleeding. Stress ulcer prophylaxis (SUP) is a drug used to prevent gastrointestinal tract injuries due to stress ulcers. The inappropriate use of SUP drugs can cause adverse drug reactions, and thus SUP drugs are only given to patients in accordance with guidelines in order to avoid the overuse of SUP drugs. The aim of this present study is to analyse the suitability of SUP drug usage based on the criteria from the American Society of Health-System Pharmacists (ASHP) and the drug costs of SUP overuse.MethodsAn observational descriptive study was conducted from April 24, 2019, to May 17, 2019, in the inpatient surgical ward of Dr. Soetomo General Hospital. Data were obtained from patient medical health records.ResultsOne hundred fifty-two patients used 1404 SUP drugs. Approximately 48% of usage did not suit the ASHP criteria and was considered as medication overuse. The cost of excessive SUP usage during the study period was more than US $65, which is 30.08% of the total drug cost of prescribed stress ulcer drugs.ConclusionsThe present study suggests that the relatively high excessive drug costs for SUP show a need for monitoring of the application of SUP therapy guidelines.


2016 ◽  
Vol 64 (3) ◽  
pp. 804.1-804 ◽  
Author(s):  
J Jackson ◽  
JM Okun ◽  
N Paddu

Purpose of StudyStudies have linked the use of anti-secretory agents to nosocomial complications including Clostridium difficile–induced pseudomembranous colitis and hospital acquired pneumonia. Although there are comprehensive evidence-based guidelines for the initiation of stress ulcer prophylaxis, there are no universally accepted approaches. This has caused nationwide disorganization in current practice, which has led to their overuse. While many studies have shown the pervasiveness of stress ulcer prophylaxis overuse in the hospital setting, none have demonstrated its effect on the community through the improper discharge of patients on these medications.Methods UsedA retrospective review of patient data at a major teaching hospital in New York City was performed. During a 2 month study period, adult non-intensive care patients were randomly selected to determine the incidence of inappropriate initiation of stress ulcer prophylaxis on admission, as compared to the incidence of appropriate use. A follow-up assessment was then completed to determine the incidence of patients that were inappropriately discharged on these medications.Summary of ResultsA total of 100 randomly selected patients throughout the inpatient medicine service were analyzed. The results showed a high rate of inappropriate initiation and discharge of patients on anti-secretory agents. The study showed a 50% (n=50) incidence of overall stress ulcer prophylaxis use. Of the patients on stress ulcer prophylaxis, a 76% (n=38) incidence of inappropriate use was found. Of the patients inappropriately on stress ulcer prophylaxis, there was a 53% (n=19) incidence of inappropriate discharge home on these medications.ConclusionsThis study highlights the continued inappropriate initiation and discharge of patients on anti-secretory agents, despite mounting evidence and advisories against this practice. The use of an electronic medical record could provide an additional resource to improve quality of care. Electronic prescriptions allow for prompts that ask for a clinical indication during the prescription process. The advent of this technology may yield even more promising improvements in clinical practice, and its implementation is the current focus of a continuing study.


2016 ◽  
Vol 150 (4) ◽  
pp. S644
Author(s):  
Viveksandeep Thoguluva Chandrasekar ◽  
Michael Kosters ◽  
Aditya Kalakonda ◽  
Dinesh John ◽  
Rushikesh Shah

2003 ◽  
Vol 98 ◽  
pp. S45
Author(s):  
David F. Stein ◽  
Mezgebe Berhe ◽  
Joel Penalo ◽  
Jose Reinoso ◽  
Edwin Pena ◽  
...  

2015 ◽  
Vol 128 (8) ◽  
pp. 905-913 ◽  
Author(s):  
Mitchell S. Buckley ◽  
Andrew S. Park ◽  
Clint S. Anderson ◽  
Jeffrey F. Barletta ◽  
Dale S. Bikin ◽  
...  

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