Steroid Therapy in Cardiac Sarcoidosis

CHEST Journal ◽  
1984 ◽  
Vol 85 (3) ◽  
pp. 445-447 ◽  
Author(s):  
Tadashi Ishikawa ◽  
Hiroyuki Kondoh ◽  
Susumu Nakagawa ◽  
Yasushi Koiwaya ◽  
Kenjiro Tanaka
Keyword(s):  
Steroid Therapy ◽  
Cardiac Sarcoidosis

scholarly journals Recovery of atrioventricular block following steroid therapy in patients with cardiac sarcoidosis

2013 ◽  
Vol 62 (5) ◽  
pp. 320-325 ◽  
Author(s):  
Kenji Yodogawa ◽  
Yoshihiko Seino ◽  
Reiko Shiomura ◽  
Kenta Takahashi ◽  
Ippei Tsuboi ◽  
...  
Keyword(s):  
Atrioventricular Block ◽  
Steroid Therapy ◽  
Cardiac Sarcoidosis

Abstract 14804: Time-Course and Influencing Factors of Ventricular Tachy-Arrhythmias After Initiation of Steroid Therapy in Patients With Cardiac Sarcoidosis

Circulation ◽  
2015 ◽  
Vol 132 (suppl_3) ◽  
Author(s):  
Masato Segawa ◽  
Koji Fukuda ◽  
Makoto Nakano ◽  
Masateru Kondo ◽  
Michinori Hirano ◽  
...  
Keyword(s):  
Influencing Factors ◽  
Corticosteroid Therapy ◽  
Steroid Therapy ◽  
Time Course ◽  
Cardiac Sarcoidosis ◽  
Multivariable Analysis ◽  
Electrical Storm ◽  
Diagnostic Strategy ◽  
Positive Group ◽  
Ventricular Tachy

Introduction: It is widely known that ventricular tachy-arrhythmias (VTs) are often observed in patients with cardiac sarcoidosis (CS) as one of the presentations of poor prognosis. However, the time-course and influencing factors of VTs after the introduction of corticosteroid therapy in CS patients remain to be elucidated. Methods and Results: We examined the influence of steroid therapy on VTs in 68 consecutive CS patients in Tohoku University Hospital from October 1998 until September 2014 (57±11 years-old, M/F 18/50). CS was diagnosed based on the original guidelines for diagnosis of CS from the Japanese Ministry of Health and Welfare. Corticosteroid therapy was performed in all CS patients. VTs were defined as sustained ventricular tachycardia/fibrillation or appropriate ICD therapy events. During a mean follow-up of 5.5 years, 20 out of 68 patients (29%) experienced VTs after the initiation of corticosteroid therapy, and 14 (70%) of them had VTs in the first 12 months (Figure A). Multivariable analysis showed that the positive gallium scintigraphy was an independent risk factor for VTs (odds ratio, 17.4; 95% CI, 1.03-294, P=0.047). Survival free from VTs events was significantly lower in the Ga-positive group than in the Ga-negative group (P<0.001), where most of the events were developed in the early phase in the Ga-positive group (Figure B). Furthermore, electrical storm (ES) of VTs was noted in 10 patients (14.7%), and most of them (8 out of the 10 patients) had ES in the first 12 months, whereas the recurrence of ES was relatively low (Figure C). Conclusions: VTs or ES in CS patients was frequently noted in the first 12 months after initiation of corticosteroid therapy, possibly representing inflammatory conditions, for which Ga scintigraphy is useful diagnostic strategy and Ga-positive is an independent prognostic factor in CS.

Myocardial washout of 99mTc-tetrofosmin and response to steroid therapy in patients with cardiac sarcoidosis

2010 ◽  
Vol 24 (5) ◽  
pp. 379-385 ◽  
Author(s):  
Hirokazu Kudoh ◽  
Sei Fujiwara ◽  
Hideyuki Shiotani ◽  
Hiroya Kawai ◽  
Kenichi Hirata
Keyword(s):  
Steroid Therapy ◽  
Cardiac Sarcoidosis ◽  
99Mtc Tetrofosmin

scholarly journals Suppression of Ventricular Tachycardia Associated with Cardiac Sarcoidosis by Steroid Therapy

2007 ◽  
Vol 23 (4) ◽  
pp. 296-302 ◽  
Author(s):  
Kotaro Miyaji ◽  
Makoto Suzuki ◽  
Akira Mizukami ◽  
Ryota Iwatsuka ◽  
Reon Kumasaka ◽  
...  
Keyword(s):  
Ventricular Tachycardia ◽  
Steroid Therapy ◽  
Cardiac Sarcoidosis

scholarly journals Multimodality Imaging of Cardiac Sarcoidosis Before and After Steroid Therapy

Circulation ◽  
2006 ◽  
Vol 113 (20) ◽  
Author(s):  
Eiji Tadamura ◽  
Masaki Yamamuro ◽  
Shigeto Kubo ◽  
Shotaro Kanao ◽  
Ryohei Hosokawa ◽  
...  
Keyword(s):  
Steroid Therapy ◽  
Cardiac Sarcoidosis ◽  
Multimodality Imaging ◽  
Before And After
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