Carbon Monoxide Effect on Alveolar Epithelial Permeability

CHEST Journal ◽  
1980 ◽  
Vol 78 (5) ◽  
pp. 726-731 ◽  
Author(s):  
Alan Fein ◽  
Ronald F. Grossman ◽  
J.Gareth Jones ◽  
John Hoeffel ◽  
Donald McKay
Keyword(s):  
Carbon Monoxide ◽  
Epithelial Permeability ◽  
Alveolar Epithelial

EFFECTS OF INHALED IRON OXIDE PARTICLES ON ALVEOLAR EPITHELIAL PERMEABILITY IN NORMAL SUBJECTS

2001 ◽  
Vol 13 (12) ◽  
pp. 1065-1078 ◽  
Author(s):  
John C. Lay ◽  
Kirby L. Zeman ◽  
Andrew J. Ghio ◽  
William D. Bennett
Keyword(s):  
Iron Oxide ◽  
Normal Subjects ◽  
Epithelial Permeability ◽  
Iron Oxide Particles ◽  
Alveolar Epithelial ◽  
Oxide Particles

scholarly journals Cyclic Stretch–Induced Oxidative Stress Increases Pulmonary Alveolar Epithelial Permeability

2013 ◽  
Vol 49 (1) ◽  
pp. 156-164 ◽  
Author(s):  
Nurit Davidovich ◽  
Brian C. DiPaolo ◽  
Gladys G. Lawrence ◽  
Peter Chhour ◽  
Nadir Yehya ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Cyclic Stretch ◽  
Epithelial Permeability ◽  
Alveolar Epithelial

Evaluation of two-way protein fluxes across the alveolo-capillary membrane by scintigraphy in rats: effect of lung inflation

2007 ◽  
Vol 102 (2) ◽  
pp. 794-802 ◽  
Author(s):  
Nicolas de Prost ◽  
Didier Dreyfuss ◽  
Georges Saumon
Keyword(s):  
Airway Pressure ◽  
Endothelial Permeability ◽  
Compartment Model ◽  
Epithelial Permeability ◽  
Lung Inflation ◽  
Alveolar Epithelial ◽  
Pressure Threshold ◽  
Capillary Membrane ◽  
Four Levels

Pulmonary microvascular and alveolar epithelial permeability were evaluated in vivo by scintigraphic imaging during lung distension. A zone of alveolar flooding was made by instilling a solution containing99mTc-albumin in a bronchus. Alveolar epithelial permeability was estimated from the rate at which this tracer left the lungs. Microvascular permeability was simultaneously estimated measuring the accumulation of111In-transferrin in lungs. Four levels of lung distension (corresponding to 15, 20, 25, and 30 cmH2O end-inspiratory airway pressure) were studied during mechanical ventilation. Computed tomography scans showed that the zone of alveolar flooding underwent the same distension as the contralateral lung during inflation with gas. Increasing lung tissue stretch by ventilation at high airway pressure immediately increased microvascular, but also alveolar epithelial, permeability to proteins. The same end-inspiratory pressure threshold (between 20 and 25 cmH2O) was observed for epithelial and endothelial permeability changes, which corresponded to a tidal volume between 13.7 ± 4.69 and 22.2 ± 2.12 ml/kg body wt. Whereas protein flux from plasma to alveolar space (111In-transferrin lung-to-heart ratio slope) was constant over 120 min, the rate at which99mTc-albumin left air spaces decreased with time. This pattern can be explained by changes in alveolar permeability with time or by a compartment model including an intermediate interstitial space.

Pulmonary Alveolar Epithelial Permeability in Surgically Induced Hemorrhagic Pancreatitis in Dogs

Respiration ◽  
1980 ◽  
Vol 40 (4) ◽  
pp. 213-217
Author(s):  
R. Falls ◽  
J.E. Millen ◽  
F.L. Glauser ◽  
P. Egan ◽  
B. Roberts
Keyword(s):  
Epithelial Permeability ◽  
Alveolar Epithelial ◽  
Hemorrhagic Pancreatitis ◽  
Surgically Induced

Frequency and peak stretch magnitude affect alveolar epithelial permeability

2008 ◽  
Vol 32 (4) ◽  
pp. 854-861 ◽  
Author(s):  
T. S. Cohen ◽  
K. J. Cavanaugh ◽  
S. S. Margulies
Keyword(s):  
Epithelial Permeability ◽  
Alveolar Epithelial
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