Non-Hemic Priming Fluids for Extracorporeal Circulation* *From the Halsted Laboratory for Experimental Surgery, Department of Surgery, University of Colorado Medical Center.

1965 ◽  
Vol 48 (3) ◽  
pp. 311-318 ◽  
Author(s):  
Bruce C. Paton ◽  
Jens Rosenkrantz
Keyword(s):  
Extracorporeal Circulation ◽  
Medical Center ◽  
Experimental Surgery ◽  
University Of Colorado ◽  
Surgery Department

The Causative Organisms of Bacterial Meningitis and their Antimicrobial Resistance Profiles in Iranian Children in 2011-2016

2020 ◽  
Vol 20 (2) ◽  
pp. 229-236
Author(s):  
Sepideh Keshavarz Valian ◽  
Shima Mahmoudi ◽  
Babak Pourakbari ◽  
Maryam Banar ◽  
Mohammad Taghi Haghi Ashtiani ◽  
...  
Keyword(s):  
Antimicrobial Resistance ◽  
Bacterial Meningitis ◽  
Medical Center ◽  
Blood Cultures ◽  
Gram Positive ◽  
Gram Negative ◽  
Number Of Patients ◽  
Resistance Patterns ◽  
Iranian Children ◽  
Surgery Department

Objective: The study aimed to describe the identity and antimicrobial resistance patterns of the causative agents of bacterial meningitis in children referred to Children’s Medical Center (CMC) Hospital, Tehran, Iran. Methods: This retrospective study was performed at CMC Hospital during a six-year period from 2011 to 2016. The microbiological information of the patients with a diagnosis of bacterial meningitis was collected and the following data were obtained: patients’ age, sex, hospital ward, the results of CSF and blood cultures, and antibiotic susceptibility profiles of isolated organisms. Results: A total of 118 patients with bacterial meningitis were admitted to CMC hospital. Sixty-two percent (n=73) of the patients were male. The median age of the patients was ten months (interquartile range [IQR]: 2 months-2 years) and the majority of them (n=92, 80%) were younger than two years of age. The highest number of patients (n=47, 40%) were admitted to the surgery department. Streptococcus epidermidis was the most frequent isolated bacterium (n=27/127, 21%), followed by Klebsiella pneumoniae (n=20/127, 16%), and Staphylococcus aureus (n=16/127, 12.5%). Blood culture was positive in 28% (n=33/118) of patients. Ampicillin-sulbactam and imipenem were the most effective antibiotics against Gram-negative bacteria isolated from CSF cultures. In the case of Gram-positive organisms, ampicillinsulbactam, vancomycin, and linezolid were the best choices. Imipenem was the most active drug against Gram-negative blood pathogens. Also, ampicillin and vancomycin had the best effect on Gram-positive bacteria isolated from blood cultures. Conclusion: Results of this study provide valuable information about the antibiotic resistance profiles of the etiologic agents of childhood meningitis, which can be used for prescription of more effective empirical therapies.

scholarly journals Greater distance to an academic medical center is associated with poorer melanoma prognostic factors: The University of Colorado Experience

2017 ◽  
Vol 23 (11) ◽  
Author(s):  
Blake M Snyder ◽  
Jessica S Mounessa ◽  
Melissa Fazzari ◽  
Joseph V Caravaglio ◽  
Alexandra Kretowicz ◽  
...  
Keyword(s):  
Prognostic Factors ◽  
Medical Center ◽  
Academic Medical Center ◽  
University Of Colorado ◽  
Academic Medical ◽  
The University

Implementation of a pharmacist-provided pharmacogenomics service in an executive health program

2021 ◽  
Author(s):  
Ina Liko ◽  
Lisa Corbin ◽  
Eric Tobin ◽  
Christina L Aquilante ◽  
Yee Ming Lee
Keyword(s):  
Health Program ◽  
Medical Center ◽  
Academic Medical Center ◽  
Test Results ◽  
Sample Collection ◽  
Team Members ◽  
University Of Colorado ◽  
Academic Medical ◽  
Previous Medication ◽  
Selection Of

Abstract Disclaimer In an effort to expedite the publication of articles related to the COVID-19 pandemic, AJHP is posting these manuscripts online as soon as possible after acceptance. Accepted manuscripts have been peer-reviewed and copyedited, but are posted online before technical formatting and author proofing. These manuscripts are not the final version of record and will be replaced with the final article (formatted per AJHP style and proofed by the authors) at a later time. Purpose We describe the implementation of a pharmacist-provided pharmacogenomics (PGx) service in an executive health program (EHP) at an academic medical center. Summary As interest in genomic testing grows, pharmacists have the opportunity to advance the use of PGx in EHPs, in collaboration with other healthcare professionals. In November 2018, a pharmacist-provided PGx service was established in the EHP at the University of Colorado Hospital. The team members included 3 physicians, a pharmacist trained in PGx, a registered dietitian/exercise physiologist, a nurse, and 2 medical assistants. We conducted 4 preimplementation steps: (1) assessment of the patient population, (2) selection of a PGx test, (3) establishment of a visit structure, and (4) selection of a billing model. The PGx consultations involved two 1-hour visits. The first visit encompassed pretest PGx education, review of the patient’s current medications and previous medication intolerances, and DNA sample collection for genotyping. After this visit, the pharmacist developed a therapeutic plan based on the PGx test results, discussed the results and plan with the physician, and created a personalized PGx report. At the second visit, the pharmacist reviewed the PGx test results, personalized the PGx report, and discussed the PGx-guided therapeutic plan with the patient. Overall, the strategy worked well; minor challenges included evaluation of gene-drug pairs with limited PGx evidence, communication of information to non-EHP providers, scheduling issues, and reimbursement. Conclusion The addition of a PGx service within an EHP was feasible and provided pharmacists the opportunity to lead PGx efforts and collaborate with physicians to expand the precision medicine footprint at an academic medical center.

Pulmonary Hypertension Roundtable: Perspectives on PHA's 10th International PH Conference

2012 ◽  
Vol 11 (3) ◽  
pp. 135-140
Keyword(s):  
Pulmonary Hypertension ◽  
Medical Center ◽  
Assistant Professor ◽  
Associate Professor ◽  
Medical Director ◽  
Pulmonary Vascular Disease ◽  
University Of Utah ◽  
University Of Colorado ◽  
Assistant Director ◽  
Vanderbilt University

As a way to integrate the presentations at PHA's June scientific sessions with clinical practice, Guest Editor Karen Fagan, MD, convened a group of attendees to discuss their experience in Orlando. The discussants included Todd Bull, MD, Associate Professor, Medical Director, Anschutz Intensive Care Unit, University of Colorado, Aurora, Colorado; Anna Hemnes, MD, Assistant Director, Center for Adult Pulmonary Vascular Disease, Vanderbilt University, Nashville, Tennessee; C. Gregory Elliott, MD, Professor of Medicine, University of Utah and Medical Director, Pulmonary Hypertension Center, Intermountain Medical Center, Murray, Utah; Vinicio A. de Jesus Perez, MD, Assistant Professor in Medicine and Staff Physician, Wall Center Adult PH Clinic, Stanford University Medical Center, Palo Alto, California; and Paul B. Yu, MD, PhD, Brigham and Women's Hospital, Boston, Massachusetts.

Abstract P165: Characteristics and Predictors of Mimics and Confirmed Strokes in a Stroke Alerts System at a Large Urban Medical Center

Stroke ◽  
2021 ◽  
Vol 52 (Suppl_1) ◽  
Author(s):  
Robert G Kowalski ◽  
Jamie Pospishil ◽  
Jarrett D Leech ◽  
William J Jones
Keyword(s):  
Medical Center ◽  
Altered Mental Status ◽  
Stroke Mimics ◽  
University Of Colorado ◽  
Included Patient ◽  
Alert Program ◽  
Hospital Resources ◽  
Missed Diagnosis ◽  
The University ◽  
Onset Location

Background: Stroke alert systems provide rapid evaluation of suspected strokes to aid timely thrombolysis and mechanical thrombectomy. Given consequences of delayed or missed diagnosis, these systems are intentionally more sensitive than specific for confirmed stroke. However, substantial physician and hospital resources are involved. We sought to evaluate characteristics and predictors of stroke mimics and confirmed strokes in a large stroke alert program. Methods: The study is a retrospective investigation of the stroke alert system at the University of Colorado Hospital. Variables included patient, clinical, stroke and stroke alert characteristics, and outcome. Variables were compared for patients with confirmed stroke, and mimics. Results: Stroke alerts were evaluated in 125 patients over a one-month period in 2019. Median age was 60 years (IQR 47-72), 52% were female, 51% were white, and 24% black or African American. Median initial NIHSS score was 4 (IQR 1-11), and onset was outside the hospital in 70%. One third of stroke alerts were confirmed stroke or TIA, and 66% were mimics. Most stroke alerts were called by the departments of Emergency Medicine (78%), Medicine (10%) and Surgery (9%). The most common of more than 40 stroke alert symptoms and combinations were weakness (45%), aphasia (20%), altered mental status (16%) and facial droop or numbness (each 14%). Stroke mimics were more likely to be female (58% female vs. 41% male, OR 2.206, 95% CI 1.025-4.745, p=0.041), had better initial NIHSS scores [3 (IQR 1-9) mimics vs. 6 (IQR 2-15) stroke, p=0.015), and were more often discharged to home (77% mimics vs. 51% strokes, OR 2.051, 95% CI 1.269-3.316, p=0.004). Stroke onset location and service initiating stroke alert were not associated with confirmed stroke. Weakness was the only symptom associated with confirmed stroke (58% stroke vs. 37% mimics, OR 2.447, 95% CI 1.137-5.268, p=0.021). Conclusions: Of stroke alerts in our institution, two thirds were stroke mimics, and these were more likely to be female patients. Weakness as a stroke alert symptom, alone or with other symptoms, was associated with confirmed stroke. Additional study is warranted to improve specificity and optimize utilization of physician and hospital resources in stroke alert programs.

THE PEDIATRICIAN AND THE PUBLIC

PEDIATRICS ◽  
1950 ◽  
Vol 5 (3) ◽  
pp. 552-565
Keyword(s):  
Medical Care ◽  
Medical Center ◽  
Medical Society ◽  
State University ◽  
Community Activities ◽  
Whole School ◽  
University Of Colorado ◽  
Earning Power ◽  
The Moment ◽  
The University

THE following articles by Robert L. Stearns, President of the University of Colorado, and Ward Darley, M.D., Dean of the University of Colorado Medical Center, describe the thinking which spurs members of the faculty of the University of Colorado Schools of Medicine and Nursing to participate daily in community activities. Dr. Fred A. Humphrey, President of the Colorado State Medical Society, health offićer and general practitioner in Ft. Collins, Cob., long interested in problems of rural medical care, presents the views of a practicing physician on community responsibilities. As indicated by Dr. Darley, every modern medical center contributes to the community by training of personnel, by research, by setting standards of medical care. Dr. Harper's invitation for these articles, however, stems from his knowledge of the conscious attempt being made by this school to discharge its obligations. From the moment one joins the faculty one becomes aware of responsibilities which are partly those of any medical school, partly those of any state university. The state university, said President Stearns at a convocation of medical students and faculty, is only incidentally interested in improving the earning power of its students by providing good technical education; its primary aim is to educate for good citizenship and service to the community. Interesting results stem from acceptance of this philosophy. A group of faculty members, thinking not only of their own departments or segments of their departments, but of the whole school and the whole community, are willing to reorganize drastically the curriculum.

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