The Influence of Obstructive Sleep Apnea on Outcomes of Hospitalized Patients With Pneumonia Requiring Invasive Mechanical Ventilation: An Analysis of the Nationwide Inpatient Sample

CHEST Journal ◽  
2014 ◽  
Vol 146 (4) ◽  
pp. 506A
Author(s):  
Charlisa Gibson ◽  
Pius Ochieng ◽  
Raymond Jean ◽  
Raymonde Jean
Keyword(s):  
Mechanical Ventilation ◽  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Nationwide Inpatient Sample ◽  
Invasive Mechanical Ventilation ◽  
Hospitalized Patients ◽  
Obstructive Sleep

551 Outcomes of Sickle Cell Crisis in Relation to Pediatric Obstructive Sleep Apnea in the United States: A US Population cohort study

SLEEP ◽  
2021 ◽  
Vol 44 (Supplement_2) ◽  
pp. A218-A218
Author(s):  
Palakkumar Patel ◽  
Tomas Munoz ◽  
Pranshu Adavadkar
Keyword(s):  
Mechanical Ventilation ◽  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Sickle Cell ◽  
Invasive Mechanical Ventilation ◽  
The United States ◽  
Hospitalization Cost ◽  
Obstructive Sleep ◽  
Sickle Cell Crisis ◽  
Total Hospitalization Cost

Abstract Introduction This study aimed to quantify the impact of obstructive sleep apnea (OSA) on the mortality, morbidity, and resources utilization among children admitted with Sickle cell crisis (SCC) Methods This is a retrospective analysis using the 2016 and 2017 National Inpatient Sample Database. The Inclusion Criteria was a principal Diagnosis of SSC and age <18 years. OSA, as a Secondary Diagnosis, was identified using the appropriate ICD-10 CM codes. The Primary Outcomes were Inpatient Mortality, and secondary outcomes were: In-Hospital Length of Stay(LOS), Total hospitalization Cost, Blood transfusion (BT) requirement, and a requirement for Invasive mechanical ventilation (IMV). We used Multivariate Linear/ logistic regression to adjust for confounders including age and sex. Results Out of 36,484 children with SSC included in the study, 1450 children had OSA (SCC+OSA). SSC-OSA and SSC+OSA groups did not differ in gender, household income, and hospital characteristics, but did so in age (11.3 vs 12.4; p <0.001). OSA was most common in the age group of 13–18 (54%) and lowest in 0–4 (2.4%). Compared to SSC-OSA, the SCC+OSA cohort had significantly higher odds of mortality (adjusted OR= 11.9, [95% Confidence Interval: 1.02- 138.8],p=0.04). Additionally, SSC+OSA cohort was associated with increased odds of IMV (aOR=5.24 [CI: 1.84 – 14.8], p=0.002), longer LOS (adjusted mean difference (aMD)=0.67 [CI-0.32 – 1.02], p=<0.001), and higher hospitalization Cost (aMD=2818.76 [CI-1680- 4157], p=<0.001). No difference in BT (aOR=0.94 [CI: 0.68 – 1.29], p=0.71) was noted. Conclusion This study demonstrates that the presence of OSA is associated with detrimental outcomes in SSC with higher in-hospital mortality, higher morbidity (Invasive mechanical ventilation rate), and higher resource utilization (LOS, total hospitalization cost). More attention to the screening, early diagnosis, and appropriate treatment of OSA is imperative to improve health outcomes in children with sickle cell disease. Support (if any):

Non-Invasive Mechanical Ventilation in Chemical Lung Veterans with Obstructive Sleep Apnea

2020 ◽  
Author(s):  
Ghasem Jalali ◽  
Fariba Rezaeetalab ◽  
Fariborz Rezaeitalab ◽  
Negar Morovatdar ◽  
Mahnaz Mozdourian ◽  
...  
Keyword(s):  
Mechanical Ventilation ◽  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Invasive Mechanical Ventilation ◽  
Non Invasive ◽  
Obstructive Sleep

Obstructive Sleep Apnea as a Predictor of Clinical Deterioration in Hospitalized Patients on the Wards

CHEST Journal ◽  
2014 ◽  
Vol 146 (4) ◽  
pp. 502A
Author(s):  
Patrick Lyons ◽  
Matthew Churpek ◽  
Frank Zadravecz ◽  
Dana Edelson ◽  
Babak Mokhlesi
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Hospitalized Patients ◽  
Clinical Deterioration ◽  
Obstructive Sleep

scholarly journals Risk of Obstructive Sleep Apnea (OSA) in Hospitalized Patients

CHEST Journal ◽  
2010 ◽  
Vol 138 (4) ◽  
pp. 779A ◽  
Author(s):  
Sunita Kumar ◽  
David McElligott ◽  
Amit Goyal ◽  
Matthew Baugh ◽  
Ramona N. Ionita
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Hospitalized Patients ◽  
Obstructive Sleep

scholarly journals Recurrent Pneumothorax with CPAP Therapy for Obstructive Sleep Apnea

2020 ◽  
Vol 2020 ◽  
pp. 1-6
Author(s):  
Kartikeya Rajdev ◽  
Pretty Sara Idiculla ◽  
Shubham Sharma ◽  
Susanna G. Von Essen ◽  
Peter J. Murphy ◽  
...  
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Diaphragmatic Hernia ◽  
Invasive Mechanical Ventilation ◽  
Positive Pressure ◽  
Cpap Therapy ◽  
Pulmonary Barotrauma ◽  
Sleep Study ◽  
Pressure Therapy ◽  
Obstructive Sleep

Pulmonary barotrauma such as pneumothorax (PTX) is a known complication of invasive mechanical ventilation. However, it is uncommonly reported with the use of noninvasive positive pressure ventilation (NPPV) and CPAP (continuous positive airway pressure) therapy. We present a case of a 66-year-old female who presented with chronic dyspnea on exertion secondary to right-sided diaphragmatic hernia. The patient also underwent a home sleep study which suggested obstructive sleep apnea (OSA) for which she was initiated on CPAP. She then underwent surgical repair of her right diaphragmatic hernia. The patient developed pneumothorax three times over the course of the following several months, once on the right side and twice on the left side. The patient’s incidences of PTX had a temporal association with the CPAP initiation. Her CPAP therapy was discontinued permanently after the third occurrence of PTX. With this case report, we highlight the risk of barotrauma with the use of CPAP for OSA. There are very few reported cases of PTX in association with NPPV therapy for OSA. The lung-protective ventilation strategies and limiting the positive airway pressures can help reduce the risk of pulmonary barotrauma with CPAP.

Prevalence of obstructive sleep apnea in patients weaned from prolonged mechanical ventilation

2020 ◽  
Author(s):  
Barbara Fusar Poli ◽  
Cecilia Burattini ◽  
Cinzia Lastoria ◽  
Nicolino Ambrosino ◽  
Piero Ceriana ◽  
...  
Keyword(s):  
Mechanical Ventilation ◽  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Prolonged Mechanical Ventilation ◽  
Obstructive Sleep
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