Efficacy and Safety of Fondaparinux for the Management of Patients With Heparin-Induced Thrombocytopenia: A Systematic Review

CHEST Journal ◽  
2014 ◽  
Vol 145 (3) ◽  
pp. 521A
Author(s):  
Catherine Ivory ◽  
Gregoire Le Gal ◽  
Marc Carrier ◽  
Marc Rodger ◽  
Catherine Code ◽  
...  
Keyword(s):  
Systematic Review ◽  
Efficacy And Safety ◽  
Heparin Induced Thrombocytopenia

Acute limb ischemia in a patient with pre-fibrotic myelofibrosis complicated by heparin-induced thrombocytopenia and thrombosis – case report and systematic review of dabigatran use

VASA ◽  
2020 ◽  
pp. 1-6 ◽  
Author(s):  
Marina Di Pilla ◽  
Stefano Barco ◽  
Clara Sacco ◽  
Giovanni Barosi ◽  
Corrado Lodigiani
Keyword(s):  
Systematic Review ◽  
Case Report ◽  
Lower Limb ◽  
Limb Ischemia ◽  
Acute Limb Ischemia ◽  
Review Of The Literature ◽  
Heparin Induced Thrombocytopenia ◽  
Lower Limb Ischemia ◽  
Vein Thrombosis ◽  
Left Lower Limb

Summary: A 49-year-old man was diagnosed with pre-fibrotic myelofibrosis after acute left lower-limb ischemia requiring amputation and portal vein thrombosis. After surgery he developed heparin-induced thrombocytopenia (HIT) with venous thromboembolism, successfully treated with argatroban followed by dabigatran. Our systematic review of the literature supports the use of dabigatran for suspected HIT.

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