Differential Characteristics of Patients With Mild Acute Respiratory Distress Syndrome Due to Community-Acquired Pneumonia Admitted to ICU

CHEST Journal ◽  
2014 ◽  
Vol 145 (3) ◽  
pp. 176A
Author(s):  
Laura Novella ◽  
Francisco Sanz ◽  
Estrella Fernández-Fabrellas ◽  
Ángela Cervera ◽  
Maria Luisa Briones ◽  
...  
Keyword(s):  
Acute Respiratory Distress Syndrome ◽  
Respiratory Distress Syndrome ◽  
Respiratory Distress ◽  
Distress Syndrome ◽  
Community Acquired Pneumonia

Therapeutic hypothermia as an adjunct to extracorporeal membrane oxygenation for acute respiratory distress and refractory hypoxemia

Perfusion ◽  
2019 ◽  
Vol 34 (5) ◽  
pp. 422-424 ◽  
Author(s):  
Jessica G Y Luc ◽  
Steven R Meyer ◽  
William J Murtha ◽  
Gurmeet Singh
Keyword(s):  
Acute Respiratory Distress Syndrome ◽  
Extracorporeal Membrane Oxygenation ◽  
Respiratory Distress Syndrome ◽  
Respiratory Distress ◽  
Therapeutic Hypothermia ◽  
Distress Syndrome ◽  
Community Acquired Pneumonia ◽  
Successful Management ◽  
Membrane Oxygenation ◽  
Refractory Hypoxemia

Legionella community–acquired pneumonia necessitating veno-venous extracorporeal membrane oxygenation for severe acute respiratory distress syndrome has been reported in adults. However, few options remain in cases of refractory hypoxemia on veno-venous extracorporeal membrane oxygenation. Herein, we describe adjunctive extended therapeutic hypothermia for refractory hypoxemia despite veno-venous extracorporeal membrane oxygenation for successful management of severe acute respiratory distress syndrome secondary to Legionella.

scholarly journals Serum Exosomal MicroRNAs Predict Acute Respiratory Distress Syndrome Events in Patients with Severe Community-Acquired Pneumonia

2019 ◽  
Vol 2019 ◽  
pp. 1-11 ◽  
Author(s):  
Xu Wu ◽  
Chengzhi Wu ◽  
Wenyu Gu ◽  
Haiying Ji ◽  
Lei Zhu
Keyword(s):  
Acute Respiratory Distress Syndrome ◽  
Respiratory Distress Syndrome ◽  
Respiratory Distress ◽  
Distress Syndrome ◽  
Area Under The Curve ◽  
Roc Curves ◽  
Community Acquired Pneumonia ◽  
Operating Characteristics ◽  
Predictive Values ◽  
Severe Community Acquired Pneumonia

Background. Severe community-acquired pneumonia (SCAP) requiring intensive care unit (ICU) treatment commonly causes acute respiratory distress syndrome (ARDS) with high mortality. This study was aimed at evaluating whether microRNAs (miRNAs) in circulating exosomes have the predictive values for patients at risk of developing ARDS due to SCAP. Methods. ARDS/ALI-relevant miRNAs were obtained by literature search. Exosomes in serum were isolated by ultracentrifugation method and identified by Transmission Electron Microscopy. Then the miR profiling in the exosomes using real-time PCR was analyzed in SCAP patients with or without ARDS. Moreover, multivariate Cox proportional regression analysis was performed to estimate the odds ratio of miRNA for the occurrence of ARDS and prognosis. The receiver operating characteristics (ROC) curves were calculated to discriminate ARDS cases. Finally, the Kaplan-Meier curve using log-rank method was performed to test the equality for survival distributions with different miRNA classifiers. Results. A total of 53 SCAP patients were finally recruited. Ten miRNAs were picked out. Further, a subset of exosomal miRNAs, including the miR-146a, miR-27a, miR-126, and miR-155 in ARDS group exhibited significantly elevated levels than those in non-ARDS group. The combined expression of miR-126, miR-27a, miR-146a, and miR-155 predicted ARDS with an area under the curve of 0.909 (95 % CI 0.815 –1). Only miR-126 was selected to have potential to predict the 28-day mortality (OR=1.002, P=0.024) with its median value classifier. Conclusions. The altered levels of circulating exosomal microRNAs may be useful biologic confirmation of ARDS in patients with SCAP.

Severe Sepsis and Acute Respiratory Distress Syndrome From Community-Acquired Legionella Pneumonia: Case Report

2007 ◽  
Vol 16 (3) ◽  
pp. 320-317 ◽  
Author(s):  
Dominic DeMello ◽  
Laura Kierol-Andrews ◽  
Paul J. Scalise
Keyword(s):  
Intensive Care Unit ◽  
Acute Respiratory Distress Syndrome ◽  
Respiratory Distress Syndrome ◽  
Respiratory Distress ◽  
Legionella Pneumophila ◽  
Distress Syndrome ◽  
Community Acquired Pneumonia ◽  
Antigen Test ◽  
Pneumonia Case ◽  
Legionella Pneumonia

A case of a young man with community-acquired pneumonia, severe acute respiratory distress syndrome, and sepsis is reported. Treatment with antibiotics and various modes of mechanical ventilation in the intensive care unit were unsuccessful. A urinary legionella antigen test was positive for Legionella pneumophila.

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