A Randomized Trial Comparing Weaning From Mechanical Ventilation on Pressure Support vs. Proportional Assist Ventilation: A Pilot Study

CHEST Journal ◽  
2013 ◽  
Vol 144 (4) ◽  
pp. 892A
Author(s):  
Karen Bosma ◽  
Brooke Read ◽  
Mohammad Nikoo ◽  
Tracey Bentall ◽  
Chris Harris ◽  
...  
Keyword(s):  
Mechanical Ventilation ◽  
Pilot Study ◽  
Randomized Trial ◽  
Pressure Support ◽  
Weaning From Mechanical Ventilation ◽  
Proportional Assist Ventilation

A Pilot Randomized Trial Comparing Weaning From Mechanical Ventilation on Pressure Support Versus Proportional Assist Ventilation*

2016 ◽  
Vol 44 (6) ◽  
pp. 1098-1108 ◽  
Author(s):  
Karen J. Bosma ◽  
Brooke A. Read ◽  
Mohammad J. Bahrgard Nikoo ◽  
Philip M. Jones ◽  
Fran A. Priestap ◽  
...  
Keyword(s):  
Mechanical Ventilation ◽  
Randomized Trial ◽  
Pressure Support ◽  
Weaning From Mechanical Ventilation ◽  
Proportional Assist Ventilation

scholarly journals Proportional assist ventilation versus pressure support ventilation for weaning from mechanical ventilation in adults: a meta-analysis and trial sequential analysis

Critical Care ◽  
2020 ◽  
Vol 24 (1) ◽  
Author(s):  
Liang-Jun Ou-Yang ◽  
Po-Huang Chen ◽  
Hong-Jie Jhou ◽  
Vincent Yi-Fong Su ◽  
Cho-Hao Lee
Keyword(s):  
Mechanical Ventilation ◽  
Pressure Support Ventilation ◽  
Sequential Analysis ◽  
Pressure Support ◽  
Meta Analysis ◽  
Trial Sequential Analysis ◽  
Proportional Assist Ventilation ◽  
Support Ventilation ◽  
Mechanical Ventilation Duration ◽  
Significant Difference

Abstract Background Pressure support ventilation (PSV) is the prevalent weaning method. Proportional assist ventilation (PAV) is an assisted ventilation mode, which is recently being applied to wean the patients from mechanical ventilation. Whether PAV or PSV is superior for weaning remains unclear. Methods Eligible randomized controlled trials published before April 2020 were retrieved from databases. We calculated the risk ratio (RR) and mean difference (MD) with 95% confidence intervals (CIs). Results Seven articles, involving 634 patients, met the selection criteria. Compared to PSV, PAV was associated with a significantly higher rate of weaning success (fixed-effect RR 1.16; 95% CI 1.07–1.26; I2 = 0.0%; trial sequential analysis-adjusted CI 1.03–1.30), and the trial sequential monitoring boundary for benefit was crossed. Compared to PSV, PAV was associated with a lower proportion of patients requiring reintubation (RR 0.49; 95% CI 0.28–0.87; I2 = 0%), a shorter ICU length of stay (MD − 1.58 (days), 95% CI − 2.68 to − 0.47; I2 = 0%), and a shorter mechanical ventilation duration (MD − 40.26 (hours); 95% CI − 66.67 to − 13.84; I2 = 0%). There was no significant difference between PAV and PSV with regard to mortality (RR 0.66; 95% CI 0.42–1.06; I2 = 0%) or weaning duration (MD − 0.01 (hours); 95% CI − 1.30–1.28; I2 = 0%). Conclusion The results of the meta-analysis suggest that PAV is superior to PSV in terms of weaning success, and the statistical power is confirmed using trial sequential analysis. Graphical abstract

Respiratory load compensation during mechanical ventilation—proportional assist ventilation with load-adjustable gain factors versus pressure support

2006 ◽  
Vol 32 (5) ◽  
pp. 692-699 ◽  
Author(s):  
Eumorfia Kondili ◽  
George Prinianakis ◽  
Christina Alexopoulou ◽  
Eleftheria Vakouti ◽  
Maria Klimathianaki ◽  
...  
Keyword(s):  
Mechanical Ventilation ◽  
Pressure Support ◽  
Proportional Assist Ventilation ◽  
Load Compensation
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