Mediastinal Infection With Candida glabrata in an Immunocompetent Patient

CHEST Journal ◽  
2013 ◽  
Vol 144 (4) ◽  
pp. 59A
Author(s):  
Christine Charaf ◽  
Rohan Mankikar ◽  
Eric Flenaugh ◽  
Kenneth Franco
Keyword(s):  
Candida Glabrata ◽  
Immunocompetent Patient ◽  
Mediastinal Infection

scholarly journals Brain abscess due to Candida glabrata in an immunocompetent patient. A case report with update and literature review

IDCases ◽  
2020 ◽  
Vol 22 ◽  
pp. e00996
Author(s):  
Khaled Radhouane ◽  
Aziz Bedioui ◽  
Mohamed Dehmani Yedeas ◽  
Souheil Zayet ◽  
Maroua Jebari ◽  
...  
Keyword(s):  
Case Report ◽  
Literature Review ◽  
Brain Abscess ◽  
Candida Glabrata ◽  
Immunocompetent Patient

Candida Glabrata and Candida Tropicalis in an Immunocompetent Patient

2015 ◽  
Vol 28 (3) ◽  
pp. 284-287 ◽  
Author(s):  
Leslie A. Hamilton ◽  
Nicholas R. Lockhart ◽  
Michael R. Crain
Keyword(s):  
Blood Culture ◽  
Bronchoalveolar Lavage ◽  
Candida Glabrata ◽  
The United States ◽  
Immunocompetent Patient ◽  
Hospital Acquired Pneumonia ◽  
Tract Infections ◽  
Hospital Acquired ◽  
Immunocompetent Patients ◽  
Candida Pneumonia

Objective: To report a case of Candida glabrata and tropicalis pneumonia in an immunocompetent patient. Case Summary: A 72-year-old male was transferred from an outside institution due to worsening respiratory status, acute kidney injury secondary to intravenous contrast media, sepsis, and pneumonia with fever and leukocytosis. Upon admission, he was initiated on treatment for hospital-acquired pneumonia, but was also concomitantly tested for many other opportunistic infections due to his recent month-long trip to Ecuador where he participated in a tribal treatment for neuropathy that involved direct exposure to dead guinea pigs. With completion of cultures and bronchoalveolar lavage, C. glabrata was identified in the blood culture and C. glabrata and C. tropicalis in the bronchoalveolar lavage specimen. One month later, he was admitted due to recurrent pneumonia. The patient unfortunately expired during the second admission, due to complications from chronic respiratory pulmonary disease and pneumonia. Discussion: Initially, this patient was treated for hospital-acquired pneumonia, but due to a recent trip to Ecuador, it was soon discovered that this patient had developed an invasive Candida pneumonia. His pulmonary biopsies showed growth of invasive C. glabrata and C. tropicalis, while his blood culture showed C. glabrata. Candida-related lower respiratory tract infections are exceptionally rare in immunocompetent patients and require histopathologic evidence to confirm the diagnosis. A second blood culture showed that the C. glabrata was still present and the patient had worsening leukocytosis, so micafungin was added to his antimicrobial therapy. Conclusion: It is understood that pneumonia is rarely caused by Candida species in patients who are admitted to the hospital. However, health care professionals should be aware that Candida pneumonia should be suspected as part of the differential diagnosis even in immunocompetent patients, particularly if they have recently traveled outside the United States.

scholarly journals Expanded access use of rezafungin for salvage therapy of invasive Candida glabrata infection: A case report

2021 ◽  
Author(s):  
Alina Adeel ◽  
Ming D Qu ◽  
Efaza Siddiqui ◽  
Stuart M Levitz ◽  
Richard T Ellison
Keyword(s):  
Candida Glabrata ◽  
Graft Infection ◽  
Multidrug Resistant ◽  
Phase Iii ◽  
Vascular Graft Infection ◽  
Expanded Access ◽  
Mediastinal Infection ◽  
Phase Iii Trials ◽  
One Year ◽  
Long Acting

Abstract Rezafungin is a semi-synthetic, long acting echinocandin with broad spectrum activity against many Candida species (spp)., and Aspergillus spp., including subset of drug-resistant strains. It is currently in phase III trials and was found to be safe and effective for treatment of candidemia and/or invasive Candida infections in a phase II trial. However, there are no long-term safety or efficacy data. We report on the successful ongoing compassionate use of rezafungin obtained through expanded access for over one year in a patient with a multidrug-resistant Candida glabrata mediastinal infection from a vascular graft infection and retained foreign material.

A Case of Cryptococcal Abscess Involving Deep Neck Space in an Immunocompetent Patient

2011 ◽  
Vol 54 (9) ◽  
pp. 638
Author(s):  
Soo-Wan Park ◽  
Jae-Young Choi ◽  
Ah-Yong Kim ◽  
Dong-Sik Chang
Keyword(s):  
Immunocompetent Patient

A Rare Case of Tuberculous Prostatitis

2016 ◽  
Vol 1 (2) ◽  
pp. 33
Author(s):  
Nurul Yaqeen Mohd Esa ◽  
Mohammad Hanafiah ◽  
Marymol Koshy ◽  
Hilmi Abdullah ◽  
Ahmad Izuanuddin Ismail ◽  
...  
Keyword(s):  
Rare Case ◽  
Correct Diagnosis ◽  
Immunocompetent Patient ◽  
Clinical Suspicion ◽  
Tuberculosis Infection ◽  
Advanced Age ◽  
Immunocompromised Patients ◽  
Prostatic Biopsy ◽  
High Clinical Suspicion

Tuberculous prostatitis is an uncommon form of tuberculosis infection. It is commonly seen in immunocompromised patients and in those of middle or advanced age. The diagnosis is often not straight forward due to the nature of its presentation. We report a case of tuberculous prostatitis in a young, healthy and immunocompetent patient, who initially presented with respiratory features, followed by episodes of seizures and testicular swelling. He was finally diagnosed with tuberculous prostatitis after prostatic biopsy. This case illustrates that in a high TB prevalence environment, when symptoms warrant, there should be a high clinical suspicion coupled with a thorough approach in order to arrive at a correct diagnosis of TB prostatitis.

Severe Myelitis due to Chickenpox in an Immunocompetent Patient

2017 ◽  
Vol 13 (02) ◽  
pp. 70-72
Author(s):  
Kongkiat Kulkantrakorn ◽  
Panee Sutamnartpong
Keyword(s):  
Immunocompetent Patient
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