Metformin Associated Lactic Acidosis Mimicking Ethylene Glycol Ingestionin in an Alcoholic Patient

CHEST Journal ◽  
2013 ◽  
Vol 144 (4) ◽  
pp. 352A ◽  
Author(s):  
Rohul Amin ◽  
Robert Walter ◽  
Jessica Bunin
Keyword(s):  
Lactic Acidosis ◽  
Ethylene Glycol ◽  
Alcoholic Patient

scholarly journals Erroneously High Lactate: A Guide to Diagnosing Ethylene Glycol Poisoning

2019 ◽  
Vol 4 (2) ◽  
pp. 1-3
Author(s):  
Mayanka Kamboj ◽  
Harini Bejjanki ◽  
Saraswathi Gopal ◽  
Rupam Ruchi
Keyword(s):  
Lactic Acid ◽  
Lactic Acidosis ◽  
Ethylene Glycol ◽  
Critically Ill Patients ◽  
Poor Prognosis ◽  
Acid Level ◽  
Lactic Acid Level ◽  
Analytical Interference ◽  
Ethylene Glycol Poisoning ◽  
High Lactate

A high lactic acid level in critically ill patients is a marker of poor prognosis. However, lactic acidosis in ethylene glycol (EG) poisoning should be interpreted cautiously as analytical interference is observed with EG metabolites.

scholarly journals Survival with extreme lactic acidosis following ethylene glycol poisoning?

2008 ◽  
Vol 55 (5) ◽  
pp. 318-319 ◽  
Author(s):  
Diego Castanares-Zapatero ◽  
Catherine Fillée ◽  
Marianne Philippe ◽  
Philippe Hantson
Keyword(s):  
Lactic Acidosis ◽  
Ethylene Glycol ◽  
Ethylene Glycol Poisoning

Abdominal pain and lactic acidosis with ethylene glycol poisoning

2001 ◽  
Vol 19 (6) ◽  
pp. 529-530 ◽  
Author(s):  
Manoj Singh ◽  
Mohammed Murtaza ◽  
Nina D'souza ◽  
Isaiarasi Gnanasekaran
Keyword(s):  
Abdominal Pain ◽  
Lactic Acidosis ◽  
Ethylene Glycol ◽  
Ethylene Glycol Poisoning

scholarly journals Recurrent ‘Lactic’ Acidosis-a Cautionary Tale

2007 ◽  
Vol 6 (3) ◽  
pp. 128-130
Author(s):  
Partha Kar ◽  
◽  
V Walker ◽  
Patrick Sharp ◽  
◽  
...  
Keyword(s):  
Lactic Acid ◽  
Lactic Acidosis ◽  
Literature Review ◽  
Ethylene Glycol ◽  
Glycolic Acid ◽  
Confounding Factor ◽  
Point Of Care ◽  
Cautionary Tale ◽  
Pathological Conditions ◽  
Ethylene Glycol Poisoning

Lactic acidosis can be caused by a variety of pathological conditions. We present a case of recurrent ‘lactic’ acidosis, which was eventually diagnosed to be secondary to ethylene glycol poisoning. Though there are a handful of cases reported in the literature, it is not widely known that glycolic acid (a metabolite of ethylene glycol) is measured spuriously as lactic acid by some point of care analysers. Literature review would indicate that this is a rare but potentially confounding factor in diagnosis. Given the nature of the pathology, we would suggest that greater awareness of the problem is important.

scholarly journals Treatment of Refractory Lactic Acidosis With Thiamine Administration in a Non-alcoholic Patient

Cureus ◽  
2021 ◽  
Author(s):  
Vihitha Thota ◽  
Mahati Paravathaneni ◽  
Sudheer Konduru ◽  
Bhanusowymya C Buragamadagu ◽  
Manaswitha Thota ◽  
...  
Keyword(s):  
Lactic Acidosis ◽  
Alcoholic Patient

Spurious point-of-care lactate elevation in ethylene glycol intoxication: rediscovering a clinical pearl

2021 ◽  
Vol 14 (2) ◽  
pp. e239936
Author(s):  
Laurence Poirier-Blanchette ◽  
Camille Simard ◽  
Blair Carl Schwartz
Keyword(s):  
Lactic Acidosis ◽  
Ethylene Glycol ◽  
Mental Status ◽  
Point Of Care ◽  
Clinical Signs ◽  
Altered Mental Status ◽  
Blood Gas ◽  
Arterial Blood Gas ◽  
Arterial Blood ◽  
Renal Replacement Therapy Initiation

A 76-year-old man was found unresponsive and brought to the emergency department. Initial workup showed profound lactic acidosis on a point-of-care arterial blood gas, without clinical signs of hypoperfusion. Investigations for types A and B lactic acidosis revealed no unifying diagnosis to explain both his altered mental status and profound lactic acidosis. A toxicology workup revealed an increased osmolar gap and an elevated ethylene glycol level. The lactic acidosis and his mental status completely normalised within 8 hours of renal replacement therapy initiation and fomepizole administration. Ethylene glycol metabolites have similar molecular structure with L-lactate. Some blood gas analysers are unable to differentiate them, resulting in an artefactual lactate elevation. Our case highlights the importance of recognising a falsely elevated lactate, which should raise clinical suspicion of ethylene glycol poisoning, as the treatment is time-sensitive to prevent complications and mortality.

scholarly journals Massive lactic acidosis and ketoacidosis with glucagon deficiency in a chronic alcoholic patient

2020 ◽  
Author(s):  
P. Boudou ◽  
M. Djibré ◽  
F. Ibrahim ◽  
S. Fellahi ◽  
P. Gilon ◽  
...  
Keyword(s):  
Lactic Acidosis ◽  
Alcoholic Patient ◽  
Chronic Alcoholic
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