Comparison of Airflow Perturbation Device and Impulse Oscillometry Measurements of Airway Resistance

CHEST Journal ◽  
2012 ◽  
Vol 142 (4) ◽  
pp. 783A
Author(s):  
Peter Whitesell ◽  
John Whitesell ◽  
Jafar Vossoughi ◽  
Arthur Johnson
Keyword(s):  
Airway Resistance ◽  
Impulse Oscillometry ◽  
Airflow Perturbation Device

Dynamic airway function during exercise in COPD assessed via impulse oscillometry before and after inhaled bronchodilators.

2021 ◽  
Author(s):  
Nicholas B. Tiller ◽  
Min Cao ◽  
Fang Lin ◽  
Wei Yuan ◽  
Chu-yi Wang ◽  
...  
Keyword(s):  
Healthy Subjects ◽  
Airway Resistance ◽  
Pulmonary Ventilation ◽  
Peak Exercise ◽  
Impulse Oscillometry ◽  
Airway Function ◽  
Volume Curve ◽  
Copd Patients ◽  
Before And After ◽  
Flow Volume Curve

Introduction. Assessing airway function during exercise provides useful information regarding mechanical properties of the airways and extent of ventilatory limitation in COPD. The primary aim of this study was to use impulse oscillometry (IOS) to assess dynamic changes in airway impedance across a range of exercise intensities in GOLD 1-4 patients, before and after albuterol. A secondary aim was to assess reproducibility of IOS measures during exercise. Methods. Fifteen COPD patients (8 male; age=66±8 y; pre-bronchodilator FEV1=54.3±23.6%Pred) performed incremental cycle ergometry before and 90-min after inhaled albuterol. Pulmonary ventilation and gas exchange were measured continuously, and IOS-derived indices of airway impedance were measured every 2 min immediately preceding inspiratory capacity manoeuvres. Test-retest reproducibility of exercise IOS was assessed as mean difference between replicate tests in five healthy subjects (3 male). Results. At rest and during exercise, albuterol significantly increased airway reactance (X5), and decreased airway resistance (R5, R5-20), impedance (Z5), and end-expiratory lung volume (60±12 vs. 58±12%TLC, main effect p=0.003). At peak exercise, there were moderate-to-strong associations between IOS variables and IC, and between IOS and concavity in the expiratory limb of the flow-volume curve. Exercise IOS exhibited moderate reproducibility in healthy subjects which was strongest with R5 (mean diff. -0.01±0.05 kPa/L/s; ICC=0.68), R5-20 (mean diff. -0.004±0.028 kPa/L/s; ICC=0.65), and Z5 (mean diff. -0.006±0.021 kPa/L/s; ICC=0.69). Conclusions. Exercise evoked increases in airway resistance and decreases in reactance that were ameliorated by inhaled bronchodilators. The technique of exercise IOS may aid in the clinical assessment of dynamic airway function during exercise.

scholarly journals P122 The use of impulse oscillometry (IOS) to study fractal scaling and sample entropy in airway resistance time series in severe asthma

Thorax ◽  
2010 ◽  
Vol 65 (Suppl 4) ◽  
pp. A129-A129 ◽  
Author(s):  
I. Umar ◽  
D. Desai ◽  
S. Corkill ◽  
M. Shelley ◽  
A. Singapuri ◽  
...  
Keyword(s):  
Time Series ◽  
Severe Asthma ◽  
Airway Resistance ◽  
Sample Entropy ◽  
Impulse Oscillometry ◽  
Fractal Scaling

scholarly journals Comparative evaluation of expiratory airflow limitation between patients with COPD and BE using IOS

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Daniele Oliveira dos Santos ◽  
Larissa Perossi ◽  
Jéssica Perossi ◽  
Letícia Helena de Souza Simoni ◽  
Mayara Holtz ◽  
...  
Keyword(s):  
Respiratory Diseases ◽  
Airway Resistance ◽  
Airflow Limitation ◽  
Impulse Oscillometry ◽  
Expiratory Phase ◽  
Chronic Respiratory Diseases ◽  
Inspiratory Phase ◽  
Significant Difference ◽  
Peripheral Airway ◽  
Central Airway

AbstractImpulse oscillometry (IOS) allows evaluation of the compartmentalized resistance and reactance of the respiratory system, distinguishing central and peripheral obstruction. The IOS measurements are getting attention in the diagnosis and differentiation of chronic respiratory diseases. However, no data are available in the literature to differentiate between COPD and BE using IOS parameters. We aimed to evaluate the feasibility of IOS in the diagnosis of bronchiectasis non-cystic fibrosis (BE) in comparison to COPD. Whole breath, inspiration, expiration, and inspiratory-expiratory difference (Δ) were evaluated based on the IOS parameters: total resistance (R5), central airway resistance (R20), peripheral airway resistance (R5-R20), reactance (X5), reactance area (AX), and resonance frequency (Fres). Fifty-nine subjects (21 Healthy, 19 BE, and 19 COPD) participated in this study. It was observed a significant difference in the comparison of healthy and pulmonary disease groups (BE and COPD) for total breathing (R5-R20, X5, AX, and Fres), inspiratory phase (R5 and R5-R5), and expiratory phase (R5-R20 and X5). The comparison between BE and COPD groups showed significant difference in the expiratory phase for resistance at 5 and 20 Hz and, ΔR5 and ΔR20. The IOS evidenced an increase of R5, R20 and R5-R20 in patients with BE and COPD when compared to healthy subjects. Expiratory measures of IOS revealed increased airway resistance in COPD compared to BE patients who had similar FEV1 measured by spirometry, however, further studies are needed to confirm these differences.

scholarly journals Impulse Oscillometry May Be Useful in Evaluation of Bronchiectasis Severity and Prediction of Airway Reversibility.

2021 ◽  
Author(s):  
Cuiyan Tan ◽  
Donghai Ma ◽  
Kongqiu Wang ◽  
Changli Tu ◽  
Meizhu Chen ◽  
...  
Keyword(s):  
Airway Resistance ◽  
Severe Disease ◽  
Peripheral Resistance ◽  
Roc Curves ◽  
Small Airways ◽  
Impulse Oscillometry ◽  
Airway Diseases ◽  
The Difference ◽  
Obstructive Airway Diseases ◽  
Airway Reversibility

Abstract BackgroundImpulse oscillometry (IOS) can be used to evaluateairway impedance in patients with obstructive airway diseases. Previous studies have demonstrated that IOS parameters differ betweenbronchiectasis patients and healthy controls. This study aims to explore the usefulness of IOS in assessing disease severity and airway reversibility in bronchiectasis.MethodSeventy-four patients with non-cystic fibrosis bronchiectasis who visited our Respiratory Medicine outpatient clinic were consecutively recruited. Spirometry, plethysmography and IOS tests were performed. Patients were stratified into mild, moderate and severe disease according to Reiff, Bhalla, BSI, FACED, and BRICS scores. Airway reversibility was measured by bronchodilation test (BDT) and the result was classified as positive or negative.. ROC curves of IOS parameters was used to assess the usefulness of IOS parameters in predicting airway reversibility. Correlations between the IOS, spirometric lung function and bronchiectasis severity parameters were analysed.ResultsMany IOS parameters, such as airway resistance at 5Hz (R5), small airways resistance (R5–R20), total airway reactance (X5), resonance frequency (Fres), total airway impedance at 5Hz (Z5), and peripheral resistance (Rp) increased with increased bronchiectasis severity according to the FACED, BSI and Reiff scores. Large airway resistance (R20) and central resistance (Rc) were not significantly different among groups with differentbronchiectasis severity. The difference between R5 and R20 (R5-R20) showed 81.0% sensitivity, and 69.8%specificity in predicting the airway reversibility in bronchiectasis with AUC of 0.794 (95%CI, 0.672-0.915).ConclusionIOS measurements are useful indicators of bronchiectasis severity and may be useful for predicting the airway reversibility.

scholarly journals Comparison of Respiratory Resistance Measurements Made with an Airflow Perturbation Device with Those from Impulse Oscillometry

2013 ◽  
Vol 2013 ◽  
pp. 1-11 ◽  
Author(s):  
J. Pan ◽  
A. Saltos ◽  
D. Smith ◽  
A. Johnson ◽  
J. Vossoughi
Keyword(s):  
Mechanical System ◽  
Impulse Oscillometry ◽  
Respiratory Resistance ◽  
Limited Data ◽  
Flow Paths ◽  
Human Volunteers ◽  
Flow Generator ◽  
Sinusoidal Flow ◽  
Airflow Perturbation Device ◽  
Strong Linear Relationship

The airflow perturbation device (APD) has been developed as a portable, easy to use, and a rapid response instrument for measuring respiratory resistance in humans. However, the APD has limited data validating it against the established techniques. This study used a mechanical system to simulate the normal range of human breathing to validate the APD with the clinically accepted impulse oscillometry (IOS) technique. The validation system consisted of a sinusoidal flow generator with ten standardized resistance configurations that were shown to represent a total range of resistances from 0.12 to 0.95 kPa·L−1·s (1.2–9.7 cm H2O·L−1·s). Impulse oscillometry measurements and APD measurements of the mechanical system were recorded and compared at a constant airflow of 0.15 L·s−1. Both the IOS and APD measurments were accurate in assessing nominal resistance. In addition, a strong linear relationship was observed between APD measurements and IOS measurements (R2 = 0.999). A second series of measurements was made on ten human volunteers with external resistors added in their respiratory flow paths. Once calibrated with the mechanical system, the APD gave respiratory resistance measurements within 5% of IOS measurements. Because of their comparability to IOS measurements, APD measurements are shown to be valid representations of respiratory resistance.

Gender Differences in Airway Resistance via Impulse Oscillometry at 5Hz in Pediatric Patients

CHEST Journal ◽  
2011 ◽  
Vol 140 (4) ◽  
pp. 373A
Author(s):  
Stamatia Alexiou ◽  
Sneha Taylor ◽  
Glenn Hildreth ◽  
Kevin Maupin
Keyword(s):  
Gender Differences ◽  
Airway Resistance ◽  
Pediatric Patients ◽  
Impulse Oscillometry

scholarly journals Study the Effect of Spironolactone in Airway Resistance with Impulse Oscillometry in Patients with Congestive Heart Failure

Health ◽  
2018 ◽  
Vol 10 (05) ◽  
pp. 691-699
Author(s):  
Yousef Gholampour ◽  
Mohammad Nourizadeh ◽  
Mohammad Hasan Adel ◽  
Esmaeel Eidani ◽  
Ahmad Amin ◽  
...  
Keyword(s):  
Heart Failure ◽  
Congestive Heart Failure ◽  
Airway Resistance ◽  
Impulse Oscillometry
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