scholarly journals Health-Related Quality of Life and Impairment of Lung Function in Elderly Patients With Treated Pulmonary Tuberculosis

CHEST Journal ◽  
2012 ◽  
Vol 142 (4) ◽  
pp. 216A
Author(s):  
Mikhail Chushkin ◽  
Sergey Mandrykin ◽  
Eduard Tikhokhod ◽  
Sergey Smerdin
2020 ◽  
Vol 7 (1) ◽  
pp. e000598
Author(s):  
Michael T Durheim ◽  
Anna-Maria Hoffmann-Vold ◽  
Tomas M Eagan ◽  
Arnt-Ove Hovden ◽  
May Brit Lund ◽  
...  

IntroductionIdiopathic pulmonary fibrosis (IPF) and systemic sclerosis-associated interstitial lung disease (SSc-ILD) are fibrotic ILDs with divergent disease populations. Little is known about health-related quality of life (HRQL) in SSc-ILD relative to IPF.MethodsWe used the Kings Brief Interstitial Lung Disease Questionnaire (K-BILD) to compare HRQL in a cross-sectional study of 57 patients with IPF and 29 patients with SSc-ILD. Analysis of covariance was used to adjust for age, gender and lung function.ResultsThe unadjusted mean K-BILD score was 63.1 (95% CI 57.1 to 69.1) among patients with SSc-ILD, as compared with 54.7 (51.8–57.5) among those with IPF (p=0.005). However, this difference in HRQL was attenuated after adjustment for age, gender and lung function. In a multivariable model, only forced vital capacity was associated with K-BILD scores. K-BILD scores were correlated with both forced vital capacity and with other relevant HRQL measures, regardless of ILD diagnosis.DiscussionPatients with SSc-ILD may have better ILD-specific quality of life than patients with IPF, but this difference appears to be driven primarily by better lung function. These results underscore the impact of lung function on HRQL in fibrotic ILD and the utility of K-BILD to assess HRQL in SSc-ILD.


2013 ◽  
Vol 16 (3) ◽  
pp. A95-A96 ◽  
Author(s):  
J.A. Dujaili ◽  
A.Q. Blebil ◽  
A. Awaisu ◽  
J. Bredle ◽  
M.A. Dujaili ◽  
...  

2018 ◽  
Vol 27 (12) ◽  
pp. 3137-3143 ◽  
Author(s):  
Saniya Saleem ◽  
Amyn A. Malik ◽  
Asma Ghulam ◽  
Junaid Ahmed ◽  
Hamidah Hussain

2013 ◽  
Vol 7 ◽  
pp. CMC.S10628 ◽  
Author(s):  
Carl J. Pepine

This systematic review assessed the impact of atrial fibrillation (AF) and pharmacotherapy on health-related quality of life (HRQOL) in elderly patients. Highly prevalent in the elderly, AF is associated with morbidity and symptoms affecting HRQOL. A PubMed and EMBASE search (1999-2010) was conducted using the terms atrial fibrillation, elderly, quality of life, Medicare, and Medicaid. In all, 504 articles were identified and 15 were selected (studies examining pharmacotherapy [rate or rhythm control] and HRQOL in AF patients with a mean age > 65 years). Information, including study design, cohort size, and HRQOL instruments utilized, was extracted. Five observational studies, 5 randomized trials comparing rate and rhythm control, 3 randomized trials investigating pharmacologic agents, and 2 trials examining HRQOL, depression, and anxiety were identified. Elderly AF patients had reduced HRQOL versus patients in normal sinus rhythm, particularly in domains related to physical functioning. HRQOL may be particularly affected in older AF patients. Although data do not indicate whether a pharmacologic intervention or single treatment strategy—namely rate versus rhythm control—is better at improving HRQOL, either of these strategies and many pharmacologic interventions may improve HRQOL in elderly AF patients. Based on reviewed data, an algorithm is suggested to optimize HRQOL among elderly patients.


2015 ◽  
Vol 42 (4) ◽  
pp. 352-359 ◽  
Author(s):  
Diba Maria Sebba Tosta de Souza ◽  
Daniela Francescato Veiga ◽  
Ivan Dunshee de Abranches Oliveira Santos ◽  
Luiz Eduardo Felipe Abla ◽  
Yara Juliano ◽  
...  

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