Obstructive Sleep Apnea Is an Independent Risk Factor for Venous Thromboembolism Among Females Not Males

CHEST Journal ◽  
2010 ◽  
Vol 138 (4) ◽  
pp. 937A
Author(s):  
Ousama Dabbagh ◽  
Maneesha Sabharwal ◽  
Oudai Hassan ◽  
Vaibhav Bora ◽  
Lakshmi Chauhan ◽  
...  
Keyword(s):  
Obstructive Sleep Apnea ◽  
Risk Factor ◽  
Venous Thromboembolism ◽  
Sleep Apnea ◽  
Independent Risk Factor ◽  
Obstructive Sleep

Sleep apnea and venous thromboembolism

2015 ◽  
Vol 114 (11) ◽  
pp. 958-963 ◽  
Author(s):  
Camilla Mattiuzzi ◽  
Massimo Franchini ◽  
Giuseppe Lippi
Keyword(s):  
Pulmonary Embolism ◽  
Obstructive Sleep Apnea ◽  
Risk Factor ◽  
Venous Thromboembolism ◽  
Sleep Apnea ◽  
Independent Risk Factor ◽  
Case Control ◽  
Vein Thrombosis ◽  
Obstructive Sleep ◽  
Deep Vein

SummaryRecent evidence suggests that obstructive sleep apnea is a significant and independent risk factor for a number of cardiovascular disorders. Since the association between obstructive sleep apnea and cardiovascular disease is mediated by endothelial dysfunction, hypercoagulability and platelet abnormalities, we sought to investigate whether sleep apnea may also be considered a risk factor for venous thromboembolism (VTE). We carried out an electronic search in Medline and Scopus using the keywords “apnea” OR “apnoea” AND “venous thromboembolism” OR “deep vein thrombosis” OR “pulmonary embolism” in “Title/Abstract/Keywords”, with no language or date restriction. Fifteen studies (8 case-control, 4 retrospective observational, 2 prospective case-control and 1 prospective observational) were finally selected for this systematic review. In all studies except one (14/15; 93%), obstructive sleep apnea was found to be an independent risk factor for VTE, either deep-vein thrombosis (DVT) or pulmonary embolism (PE). In the two prospective case-control studies the risk of DVT or PE was found to be two-to three-fold higher in patients with obstructive sleep apnea than in those without. In conclusion, the current epidemiological evidence supports the hypothesis that obstructive sleep apnea may be an independent risk factor for VTE.

scholarly journals Obstructive Sleep Apnea is an Independent Risk Factor for Hospital Readmission

2018 ◽  
Vol 14 (05) ◽  
pp. 753-758 ◽  
Author(s):  
Nicholas J. Scalzitti ◽  
Peter D. O'Connor ◽  
Skyler W. Nielsen ◽  
James K. Aden ◽  
Matthew S. Brock ◽  
...  
Keyword(s):  
Obstructive Sleep Apnea ◽  
Risk Factor ◽  
Sleep Apnea ◽  
Hospital Readmission ◽  
Independent Risk Factor ◽  
Obstructive Sleep

scholarly journals Obstructive Sleep Apnea as an Independent Risk Factor for Stroke and Mortality

Stroke ◽  
2006 ◽  
Vol 37 (5) ◽  
pp. 1150-1150 ◽  
Author(s):  
Miguel A. Arias ◽  
Alberto Alonso-Fernández ◽  
Francisco García-Río
Keyword(s):  
Obstructive Sleep Apnea ◽  
Risk Factor ◽  
Sleep Apnea ◽  
Independent Risk Factor ◽  
Obstructive Sleep

scholarly journals Alcohol as an independent risk factor for obstructive sleep apnea

2021 ◽  
Author(s):  
Shanshan Yang ◽  
Xinhong Guo ◽  
Wei Liu ◽  
Yanhua Li ◽  
Yunxi Liu
Keyword(s):  
Obstructive Sleep Apnea ◽  
Risk Factor ◽  
Sleep Apnea ◽  
Alcohol Consumption ◽  
Independent Risk Factor ◽  
Control Group ◽  
Logistic Regression Models ◽  
Obstructive Sleep ◽  
The Relationship ◽  
Control Study

Abstract Background To determine if alcohol consumption is a risk factor for obstructive sleep apnea (OSA) and nocturnal oxygen desaturation. Methods This case–control study evaluated patients with confirmed OSA and a control group using polysomnography (PSG). Two doctors who have worked in this field for more than 5 years provided a blinded interpretation of the patients’ monitoring results. Logistic regression models were used to identify the odds ratio (OR) for alcohol consumption on OSA. Results A total of 793 patients were enrolled in this study. Compared with those who did not consume alcohol, those consuming alcohol had a higher risk of OSA (OR 2.03, 95% CI 1.30–3.17) after adjustment. Regarding the risk of OSA after adjusting for former drinkers and current ones, the ORs were 1.96 (95% CI 1.19–3.22) and 2.22 (95% CI 1.06–4.63), respectively. And the P for trend = 0.002. The β of former drinkers and the current ones were 3.448 and 4.560 after adjustment; P for trend was 0.006. The relationship may have gender difference, and alcohol consumption was associated with AHI in female significantly (β = 10.190 and 15.395 for former and current drinkers, respectively, in females after adjustment, P for trend = 0.002). Conclusions In this study, we found that alcohol consumption was an independent risk factor of OSA and OSA with hypoxia, and alcohol consumption was related to AHI significantly after adjustment, especially in female. In order to reduce the risk and severity of OSA, it is suggested that people should avoid drinking, and drinkers should abstain from drinking.

Is Obstructive Sleep Apnea an Independent Risk Factor for Stroke?

2010 ◽  
Vol 16 (4) ◽  
pp. 269-273 ◽  
Author(s):  
Dan J. Capampangan ◽  
Kay E. Wellik ◽  
James M. Parish ◽  
Maria I. Aguilar ◽  
Charlene R. Hoffman Snyder ◽  
...  
Keyword(s):  
Obstructive Sleep Apnea ◽  
Risk Factor ◽  
Sleep Apnea ◽  
Independent Risk Factor ◽  
Obstructive Sleep

scholarly journals Sleep and Diabetes

2010 ◽  
Vol 2010 ◽  
pp. 1-9 ◽  
Author(s):  
Swetha Bopparaju ◽  
Salim Surani
Keyword(s):  
Myocardial Infarction ◽  
Insulin Resistance ◽  
Metabolic Syndrome ◽  
Obstructive Sleep Apnea ◽  
Risk Factor ◽  
Sleep Apnea ◽  
Independent Risk Factor ◽  
The Metabolic Syndrome ◽  
Obstructive Sleep ◽  
Independent Association

Sleep apnea is clinically recognized as a heterogeneous group of disorders characterized by recurrent apnea and/or hypopnea. Its prevalence ranges from 4% to 24%. It has been implicated as an independent risk factor for several conditions such as hypertension, stroke, arrhythmia, and myocardial infarction. Recently data has been emerging which suggests an independent association of obstructive sleep apnea with several components of the metabolic syndrome, particularly insulin resistance and abnormalities in lipid metabolism. We hereby review the salient features of the association between sleep and diabetes.

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