Intermittent Short-term Negative Pressure Ventilation and Increased Oxygenation in COPD Patients with Severe Hypercapnic Respiratory Failure

CHEST Journal ◽  
1991 ◽  
Vol 100 (2) ◽  
pp. 455-459 ◽  
Author(s):  
Jesús M. Sauret ◽  
Anna C. Guitart ◽  
Guillermo Rodríguez-Froján ◽  
Raimond Cornudella
Keyword(s):  
Respiratory Failure ◽  
Negative Pressure ◽  
Short Term ◽  
Hypercapnic Respiratory Failure ◽  
Negative Pressure Ventilation ◽  
Copd Patients

Nasal High Flow Use in COPD Patients with Hypercapnic Respiratory Failure: Treatment Algorithm & Review of the Literature

2020 ◽  
Vol 17 (1) ◽  
pp. 101-111 ◽  
Author(s):  
Ioannis Pantazopoulos ◽  
Zoi Daniil ◽  
Melanie Moylan ◽  
Konstantinos Gourgoulianis ◽  
Athanasios Chalkias ◽  
...  
Keyword(s):  
Respiratory Failure ◽  
Treatment Algorithm ◽  
High Flow ◽  
Review Of The Literature ◽  
Hypercapnic Respiratory Failure ◽  
Failure Treatment ◽  
Copd Patients

scholarly journals Maintenance Negative Pressure Ventilation Improves Survival in COPD Patients with Exercise Desaturation

2019 ◽  
Vol 8 (4) ◽  
pp. 562
Author(s):  
Hung-Yu Huang ◽  
Chun-Yu Lo ◽  
Lan-Yan Yang ◽  
Fu-Tsai Chung ◽  
Te-Fang Sheng ◽  
...  
Keyword(s):  
Lung Function ◽  
Negative Pressure ◽  
Significant Risk ◽  
Forced Expiratory Volume ◽  
Walking Distance ◽  
Chronic Obstructive ◽  
Negative Pressure Ventilation ◽  
Risk Of Death ◽  
Copd Patients

Negative pressure ventilation (NPV), when used as an adjuvant to pulmonary rehabilitation, improves lung function, increases exercise capacity, and reduces exacerbations. The aim of this study was to determine whether maintenance NPV improves long-term clinical outcomes and reduces mortality in patients with chronic obstructive pulmonary disease (COPD). Between 2003 and 2009, 341 patients were treated for COPD either with or without hospital-based NPV. We measured forced expiratory volume in one second (FEV1), 6-min walking distance (6MWD), and oxygen saturation by pulse oximetry (SpO2) during a 6-min walk test (6MWT) every 3–6 months. Desaturation (D) during the 6MWT was defined as a reduction in SpO2 of ≥10% from baseline. The NPV group had a better survival outcome than the Non-NPV group. The 8-year survival probabilities for the NPV and Non-NPV groups were 60% and 20%, respectively (p < 0.01). Baseline desaturation was a significant risk factor for death, and the risk of death increased with desaturation severity (SpO2 80~89: hazard ratios (HR) 2.7, 95% confidence interval (CI) 1.4–5.3; SpO2 < 80: HR 3.1, 95% CI 1.3–7.4). The NPV group had a slower decline in lung function and 6MWD. The NPV + D and Non-NPV+D had a threefold and fourfold increase in the risks of all-cause mortality compared with the NPV-ND, respectively. Maintenance non-invasive NPV reduced long-term mortality in COPD patients. The desaturating COPD patients had an increased mortality risk compared with non-desaturating COPD patients.

scholarly journals Prehospital Management of COPD Patients in Respiratory Failure and Short-term Outcome

CHEST Journal ◽  
2013 ◽  
Vol 144 (4) ◽  
pp. 724A
Author(s):  
Jerome Cuny ◽  
Guilaume Campagne ◽  
Nathalie Assez ◽  
Patrick Goldstein ◽  
Eric Wiel
Keyword(s):  
Respiratory Failure ◽  
Short Term ◽  
Term Outcome ◽  
Short Term Outcome ◽  
Copd Patients ◽  
Prehospital Management
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