Endobronchial Ultrasonography-Guided Transbronchial Needle Aspiration Increases the Diagnostic Yield of Peripheral Pulmonary Lesions

CHEST Journal ◽  
2009 ◽  
Vol 136 (1) ◽  
pp. 229-236 ◽  
Author(s):  
Tung-Ying Chao ◽  
Min-Te Chien ◽  
Chien-Hao Lie ◽  
Yu-Hsiu Chung ◽  
Jui-Long Wang ◽  
...  
Keyword(s):  
Diagnostic Yield ◽  
Needle Aspiration ◽  
Transbronchial Needle Aspiration ◽  
Pulmonary Lesions ◽  
Endobronchial Ultrasonography ◽  
Peripheral Pulmonary Lesions

scholarly journals Radial-probe EBUS for the diagnosis of peripheral pulmonary lesions

2016 ◽  
Vol 42 (4) ◽  
pp. 248-253 ◽  
Author(s):  
Marcia Jacomelli ◽  
Sergio Eduardo Demarzo ◽  
Paulo Francisco Guerreiro Cardoso ◽  
Addy Lidvina Mejia Palomino ◽  
Viviane Rossi Figueiredo
Keyword(s):  
Diagnostic Yield ◽  
Pulmonary Nodules ◽  
High Sensitivity ◽  
Needle Aspiration ◽  
Tertiary Hospital ◽  
Target Lesion ◽  
Transbronchial Needle Aspiration ◽  
Pulmonary Lesions ◽  
Mean Diameter ◽  
Peripheral Pulmonary Lesions

ABSTRACT Objective: Conventional bronchoscopy has a low diagnostic yield for peripheral pulmonary lesions. Radial-probe EBUS employs a rotating ultrasound transducer at the end of a probe that is passed through the working channel of the bronchoscope. Radial-probe EBUS facilitates the localization of peripheral pulmonary nodules, thus increasing the diagnostic yield. The objective of this study was to present our initial experience using radial-probe EBUS in the diagnosis of peripheral pulmonary lesions at a tertiary hospital. Methods: We conducted a retrospective analysis of 54 patients who underwent radial-probe EBUS-guided bronchoscopy for the investigation of pulmonary nodules or masses between February of 2012 and September of 2013. Radial-probe EBUS was performed with a flexible 20-MHz probe, which was passed through the working channel of the bronchoscope and advanced through the bronchus to the target lesion. For localization of the lesion and for collection procedures (bronchial brushing, transbronchial needle aspiration, and transbronchial biopsy), we used fluoroscopy. Results: Radial-probe EBUS identified 39 nodules (mean diameter, 1.9 ± 0.7 cm) and 19 masses (mean diameter, 4.1 ± 0.9 cm). The overall sensitivity of the method was 66.7% (79.5% and 25.0%, respectively, for lesions that were visible and not visible by radial-probe EBUS). Among the lesions that were visible by radial-probe EBUS, the sensitivity was 91.7% for masses and 74.1% for nodules. The complications were pneumothorax (in 3.7%) and bronchial bleeding, which was controlled bronchoscopically (in 9.3%). Conclusions: Radial-probe EBUS shows a good safety profile, a low complication rate, and high sensitivity for the diagnosis of peripheral pulmonary lesions.

scholarly journals Transbronchial needle aspiration in peripheral pulmonary lesions: a systematic review and meta-analysis

2016 ◽  
Vol 48 (1) ◽  
pp. 196-204 ◽  
Author(s):  
Michele Mondoni ◽  
Giovanni Sotgiu ◽  
Martina Bonifazi ◽  
Simone Dore ◽  
Elena Maria Parazzini ◽  
...  
Keyword(s):  
Systematic Review ◽  
Diagnostic Yield ◽  
Meta Analysis ◽  
Sampling Technique ◽  
Needle Aspiration ◽  
Lesion Size ◽  
Transbronchial Needle Aspiration ◽  
Pulmonary Lesions ◽  
Site Evaluation ◽  
Peripheral Pulmonary Lesions

Fluoroscopy-guided transbronchial needle aspiration (TBNA) has long been used in the diagnosis of peripheral pulmonary lesions (PPLs), although its diagnostic performance varies considerably.We conducted a systematic review and meta-analysis evaluating the accuracy of TBNA in the diagnosis of PPLs, comparing its diagnostic yield with transbronchial biopsy (TBB) and assessing the main predictors of a successful aspirate.In 18 studies, the overall TBNA yield was 0.53 (95% CI 0.44–0.61). TBNA showed a higher accuracy when directly compared to TBB (0.60 (95% CI 0.49–0.71) versus 0.45 (95% CI 0.37–0.54)). The subgroup analyses documented a higher TBNA yield when the computed tomography (CT) bronchus sign was present (0.70 (95% CI 0.63–0.77) versus 0.51 (95% CI 0.38–0.64)), when rapid on-site evaluation (ROSE) was performed (0.62 (95% CI 0.43–0.79) versus 0.51 (95% CI 0.42–0.60)), in the case of malignant lesions (0.55 (95% CI 0.44–0.66) versus 0.17 (95% CI 0.11–0.24)) and for lesions >3 cm (0.81 (95% CI 0.73–0.87) versus 0.55 (95% CI 0.47–0.63)).Conventional TBNA is a useful sampling technique for the diagnosis of PPL, with a higher diagnostic yield than TBB. The presence of CT bronchus sign, an underlying malignant process, lesion size >3 cm and ROSE employment are predictors of a higher yield.

Performance characteristics and predictors of yield from transbronchial needle aspiration in the diagnosis of peripheral pulmonary lesions

Respirology ◽  
2011 ◽  
Vol 16 (7) ◽  
pp. 1144-1149 ◽  
Author(s):  
ROCCO TRISOLINI ◽  
ALESSANDRA CANCELLIERI ◽  
CARMINE TINELLI ◽  
DANIELA PAIOLI ◽  
LUIGIA SCUDELLER ◽  
...  
Keyword(s):  
Needle Aspiration ◽  
Performance Characteristics ◽  
Transbronchial Needle Aspiration ◽  
Pulmonary Lesions ◽  
Peripheral Pulmonary Lesions

Diagnostic yield of combined bronchoscopy and endobronchial ultrasonography, under LungPoint guidance for small peripheral pulmonary lesions

Respirology ◽  
2013 ◽  
Vol 18 (5) ◽  
pp. 834-839 ◽  
Author(s):  
Motohiro Tamiya ◽  
Norio Okamoto ◽  
Shinji Sasada ◽  
Takayuki Shiroyama ◽  
Naoko Morishita ◽  
...  
Keyword(s):  
Diagnostic Yield ◽  
Pulmonary Lesions ◽  
Endobronchial Ultrasonography ◽  
Peripheral Pulmonary Lesions
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