scholarly journals Evaluation of a Turbidimetric Denka Seiken C-Reactive Protein Assay for Cardiovascular Risk Estimation and Conventional Inflammation Diagnosis

2003 ◽  
Vol 49 (3) ◽  
pp. 511-512 ◽  
Author(s):  
Thomas Christian Vukovich ◽  
Stefan Mustafa ◽  
Helmut Rumpold ◽  
Oswald Wagner
Author(s):  
Snežana Jovičić ◽  
Svetlana Ignjatović ◽  
Marijana Dajak ◽  
Nada Majkić-Singh

AbstractIncreased C-reactive protein (CRP) concentration within the reference interval (<10.0mg/L) is a strong predictor of cardiovascular disease (CVD) in apparently healthy adults. Cutoff points for use of CRP in estimating CVD risk are <1, 1–3 and >3mg/L for low, average and high relative risk, respectively. For measuring CRP concentrations to assess cardiovascular risk, high-sensitivity CRP (hsCRP) assays have been developed. The aim of this study was to evaluate the analytical performance and clinical efficacy for cardiovascular risk estimation of the Olympus immunoturbidimetric latex CRP assay (sensitive application). The comparative method used was the CardioPhase* hsCRP assay, approved by the Food and Drug Administration for use in CVD risk assessment. The imprecision of the Olympus hsCRP assay in the concentration range 0.2–10.0mg/L was 0.38–8.16% within runs and 3.75–9.63% between runs. For method comparison studies, 194 fresh serum samples were selected to cover the interval 0.15–10.0mg/L CRP. Comparison of the Dade Behring and Olympus methods was performed using weighted Deming regression analysis (slope 0.99mg/L, intercept 0.002mg/L, S


2001 ◽  
Vol 47 (11) ◽  
pp. 2044-2046 ◽  
Author(s):  
Ahmad Hamwi ◽  
Thomas Vukovich ◽  
Oswald Wagner ◽  
Helmut Rumpold ◽  
Roswitha Spies ◽  
...  

2004 ◽  
Vol 43 (5) ◽  
pp. A288 ◽  
Author(s):  
Jessica L Clarke ◽  
Jeffrey L Anderson ◽  
John F Carlquist ◽  
Richard F Roberts ◽  
Benjamin D Horne ◽  
...  

2005 ◽  
Vol 95 (1) ◽  
pp. 155-158 ◽  
Author(s):  
Jessica L. Clarke ◽  
Jeffrey L. Anderson ◽  
John F. Carlquist ◽  
Richard F. Roberts ◽  
Benjamin D. Horne ◽  
...  

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