scholarly journals National pharmacological treatment trends for ankylosing spondylitis in South Korea: A national health insurance database study

PLoS ONE ◽  
2020 ◽  
Vol 15 (10) ◽  
pp. e0240155
Author(s):  
Jin-Sung Park ◽  
Jae-Young Hong ◽  
Hak-Kyu Kim ◽  
Bongmo Koo ◽  
Sang-Hee Kim ◽  
...  
Circulation ◽  
2015 ◽  
Vol 132 (suppl_3) ◽  
Author(s):  
Pil-sung Yang ◽  
Hancheol Lee ◽  
Tae-Hoon Kim ◽  
Jae-Sun Uhm ◽  
Hui-Nam Pak ◽  
...  

Introduction: Sudden cardiac arrest (SCA) is a major clinical and public health problem. South Korea is aging faster than any other country, and the disease spectrum has changed profoundly in the last few decades. The purpose of this study was to investigate the change of the incidence and outcome of SCA over the past ten years. Methods: With the use of the National Health Insurance Database Cohort (NHID-Cohort) consisting of one million patients from 2003 through 2013, we identified the patient with sudden cardiac arrest using Korean Standard Classification of Diseases, 6th Revision, code I46. Results: In all, 5,307 (0.52%) patients with SCA were identified between 2003 and 2013. SCA occurred more frequent in men (59.3%) than women (40.7%) (p<0.001). The annual incidence of SCA increased by 116.3% from 28.9 in 2003 to 62.5 in 2013 (per 100,000 person-year, p<0.001). The increase of SCA was particularly predominant in patients with ≥60 years of age (from 153.8 to 259.1 per 100,000 person-year, p<0.001) and those with low economic status (from 27.5 to 85.2 per 100,000 person-year, p<0.001). Health care cost per 100,000 person-year also increased from $65,866 in 2003 to $241,534 in 2013 (p<0.001). However, there was no significant improvement in one-month survival rate during the same period (11.9% in 2003, 13.4% in 2013, p=0.526). Conclusions: The incidence of SCA in South Korea continues to rise over the past ten years, especially in elderly people. Despite the tremendous advances in the field of cardiovascular medicine, outcome of SCA is at a standstill.


Author(s):  
Kyeongmin Kwak ◽  
Kyung Ehi Zoh ◽  
Domyung Paek

The use of asbestos has been banned since 2009 in South Korea. However, there is still a risk of exposure to environmental asbestos originating from abandoned asbestos mines. We constructed a retrospective dynamic cohort using the National Health Insurance Database of South Korea. We determined the risk of developing asbestos-related diseases (ARDs) among residents living near asbestos mines compared with those living in the control area and the general population. The risks of asbestosis (adjusted hazards ratio [HR] 65.40, 95% CI = 35.02–122.12) and pleural plaques (adjusted HR 3.55, 95% CI = 1.96–6.41) were significantly increased among residents living near the asbestos mines compared with the control area. The risk of malignant mesothelioma was increased near asbestos mines compared with the control area; however, it was not significant (adjusted HR 1.83, 95% CI = 0.61–5.47). When a separate analysis according to sex was conducted, the risk of mesothelioma among male residents was statistically significant (adjusted HR 8.30, 95% CI = 1.04–66.63), and the standardized incidence ratio (SIR) was significantly increased (SIR 3.48, 95% CI = 1.50–6.85). The risk of ARDs was increased due to environmental asbestos exposure near abandoned asbestos mines in South Korea.


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