Piperine Induces Hepatic Low-Density Lipoprotein Receptor Expression through Proteolytic Activation of Sterol Regulatory Element-Binding Proteins

Ayasa Ochiai; Shingo Miyata; Makoto Shimizu; Jun Inoue; Ryuichiro Sato

doi:10.1371/journal.pone.0139799

Piperine Induces Hepatic Low-Density Lipoprotein Receptor Expression through Proteolytic Activation of Sterol Regulatory Element-Binding Proteins

PLoS ONE ◽

10.1371/journal.pone.0139799 ◽

2015 ◽

Vol 10 (10) ◽

pp. e0139799 ◽

Cited By ~ 9

Author(s):

Ayasa Ochiai ◽

Shingo Miyata ◽

Makoto Shimizu ◽

Jun Inoue ◽

Ryuichiro Sato

Keyword(s):

Binding Proteins ◽

Regulatory Element ◽

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Receptor Expression ◽

Low Density ◽

Lipoprotein Receptor ◽

Proteolytic Activation ◽

Density Lipoprotein Receptor ◽

Sterol Regulatory Element

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Resveratrol increases the expression and activity of the low density lipoprotein receptor in hepatocytes by the proteolytic activation of the sterol regulatory element-binding proteins

Atherosclerosis ◽

10.1016/j.atherosclerosis.2011.11.006 ◽

2012 ◽

Vol 220 (2) ◽

pp. 369-374 ◽

Cited By ~ 44

Author(s):

Takuya Yashiro ◽

Manami Nanmoku ◽

Makoto Shimizu ◽

Jun Inoue ◽

Ryuichiro Sato

Keyword(s):

Binding Proteins ◽

Regulatory Element ◽

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Low Density ◽

Lipoprotein Receptor ◽

Proteolytic Activation ◽

Density Lipoprotein Receptor ◽

Sterol Regulatory Element ◽

Expression And Activity

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The effect of simvastatin on gene expression of low-density lipoprotein receptor, sterol regulatory element-binding proteins, stearoyl-CoA desaturase 1 mRNA in rat hepatic tissues

Archives of Physiology and Biochemistry ◽

10.1080/13813455.2020.1772829 ◽

2020 ◽

pp. 1-8

Author(s):

Abbas Nezhadebrahimi ◽

Hamid Sepehri ◽

Mehrdad Jahanshahi ◽

Majid Marjani ◽

Abdoljalal Marjani

Keyword(s):

Gene Expression ◽

Binding Proteins ◽

Regulatory Element ◽

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Low Density ◽

Lipoprotein Receptor ◽

Density Lipoprotein Receptor ◽

Sterol Regulatory Element ◽

Stearoyl Coa Desaturase

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Nuclear protein that binds sterol regulatory element of low density lipoprotein receptor promoter. I. Identification of the protein and delineation of its target nucleotide sequence

Journal of Biological Chemistry ◽

10.1016/s0021-9258(19)85265-1 ◽

1993 ◽

Vol 268 (19) ◽

pp. 14490-14496

Author(s):

M.R. Briggs ◽

C. Yokoyama ◽

X. Wang ◽

M.S. Brown ◽

J.L. Goldstein

Keyword(s):

Nucleotide Sequence ◽

Nuclear Protein ◽

Regulatory Element ◽

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Low Density ◽

Lipoprotein Receptor ◽

Low Density Lipoprotein Receptor ◽

Density Lipoprotein Receptor ◽

Sterol Regulatory Element

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Sterol Regulatory Element–Binding Protein-1 Determines Plasma Remnant Lipoproteins and Accelerates Atherosclerosis in Low-Density Lipoprotein Receptor–Deficient Mice

Arteriosclerosis Thrombosis and Vascular Biology ◽

10.1161/atvbaha.110.219659 ◽

2011 ◽

Vol 31 (8) ◽

pp. 1788-1795 ◽

Cited By ~ 28

Author(s):

Tadayoshi Karasawa ◽

Akimitsu Takahashi ◽

Ryo Saito ◽

Motohiro Sekiya ◽

Masaki Igarashi ◽

...

Keyword(s):

Regulatory Element ◽

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Low Density ◽

Lipoprotein Receptor ◽

Remnant Lipoproteins ◽

Density Lipoprotein Receptor ◽

Element Binding Protein ◽

Sterol Regulatory Element ◽

Deficient Mice

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Domains of transcription factor Sp1 required for synergistic activation with sterol regulatory element binding protein 1 of low density lipoprotein receptor promoter.

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.92.13.6102 ◽

1995 ◽

Vol 92 (13) ◽

pp. 6102-6106 ◽

Cited By ~ 64

Author(s):

L. Yieh ◽

H. B. Sanchez ◽

T. F. Osborne

Keyword(s):

Transcription Factor ◽

Regulatory Element ◽

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Low Density ◽

Lipoprotein Receptor ◽

Synergistic Activation ◽

Density Lipoprotein Receptor ◽

Element Binding Protein ◽

Sterol Regulatory Element

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We-W43:5 Sterol regulatory element-binding protein-2 negatively regulates low density lipoprotein receptor-related protein (LRP1) transcription

Atherosclerosis Supplements ◽

10.1016/s1567-5688(06)81320-6 ◽

2006 ◽

Vol 7 (3) ◽

pp. 331

Author(s):

V. Llorente Cortes ◽

P. Costales ◽

J. Bermues ◽

S. Camino Lopez ◽

L. Badimon

Keyword(s):

Regulatory Element ◽

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Low Density ◽

Lipoprotein Receptor ◽

Related Protein ◽

Density Lipoprotein Receptor ◽

Element Binding Protein ◽

Sterol Regulatory Element ◽

Lipoprotein Receptor Related Protein

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Cooperation by Sterol Regulatory Element-binding Protein and Sp1 in Sterol Regulation of Low Density Lipoprotein Receptor Gene

Journal of Biological Chemistry ◽

10.1074/jbc.270.3.1161 ◽

1995 ◽

Vol 270 (3) ◽

pp. 1161-1169 ◽

Cited By ~ 217

Author(s):

Hugo B. Sanchez ◽

Lynn Yieh ◽

Timothy F. Osborne

Keyword(s):

Regulatory Element ◽

Receptor Gene ◽

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Low Density ◽

Lipoprotein Receptor ◽

Low Density Lipoprotein Receptor ◽

Density Lipoprotein Receptor ◽

Element Binding Protein ◽

Sterol Regulatory Element

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The low density lipoprotein receptor in Xenopus laevis. II. Feedback repression mediated by conserved sterol regulatory element

Journal of Biological Chemistry ◽

10.1016/s0021-9258(18)99241-0 ◽

1991 ◽

Vol 266 (16) ◽

pp. 10415-10419 ◽

Cited By ~ 4

Author(s):

K.D. Mehta ◽

M.S. Brown ◽

D.W. Bilheimer ◽

J.L. Goldstein

Keyword(s):

Xenopus Laevis ◽

Regulatory Element ◽

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Low Density ◽

Lipoprotein Receptor ◽

Low Density Lipoprotein Receptor ◽

Density Lipoprotein Receptor ◽

Sterol Regulatory Element

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Hepatic tissue sterol regulatory element binding protein 2 and low-density lipoprotein receptor in nephrotic syndrome

Metabolism ◽

10.1016/j.metabol.2007.05.007 ◽

2007 ◽

Vol 56 (10) ◽

pp. 1377-1382 ◽

Cited By ~ 13

Author(s):

Choong H. Kim ◽

Hyun J. Kim ◽

Masato Mitsuhashi ◽

Nosratola D. Vaziri

Keyword(s):

Nephrotic Syndrome ◽

Regulatory Element ◽

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Hepatic Tissue ◽

Low Density ◽

Lipoprotein Receptor ◽

Density Lipoprotein Receptor ◽

Element Binding Protein ◽

Sterol Regulatory Element

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Nuclear protein that binds sterol regulatory element of low density lipoprotein receptor promoter. II. Purification and characterization

Journal of Biological Chemistry ◽

10.1016/s0021-9258(19)85266-3 ◽

1993 ◽

Vol 268 (19) ◽

pp. 14497-14504

Author(s):

X. Wang ◽

M.R. Briggs ◽

X. Hua ◽

C. Yokoyama ◽

J.L. Goldstein ◽

...

Keyword(s):

Nuclear Protein ◽

Regulatory Element ◽

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Low Density ◽

Lipoprotein Receptor ◽

Purification And Characterization ◽

Low Density Lipoprotein Receptor ◽

Density Lipoprotein Receptor ◽

Sterol Regulatory Element

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