scholarly journals Enriched Environment Protects the Optic Nerve from Early Diabetes-Induced Damage in Adult Rats

PLoS ONE ◽  
2015 ◽  
Vol 10 (8) ◽  
pp. e0136637 ◽  
Author(s):  
Damián Dorfman ◽  
Marcos L. Aranda ◽  
Ruth E. Rosenstein
Keyword(s):  
Optic Nerve ◽  
Enriched Environment ◽  
Adult Rats ◽  
Early Diabetes

Short-Term Exposure to Enriched Environment in Adult Rats Restores MK-801-Induced Cognitive Deficits and GABAergic Interneuron Immunoreactivity Loss

2017 ◽  
Vol 55 (1) ◽  
pp. 26-41 ◽  
Author(s):  
Ane Murueta-Goyena ◽  
Naiara Ortuzar ◽  
Pascual Ángel Gargiulo ◽  
José Vicente Lafuente ◽  
Harkaitz Bengoetxea
Keyword(s):  
Cognitive Deficits ◽  
Enriched Environment ◽  
Gabaergic Interneuron ◽  
Short Term ◽  
Adult Rats ◽  
Mk 801 ◽  
Short Term Exposure

A new type of Schwann cell graft transplantation to promote optic nerve regeneration in adult rats

2010 ◽  
Vol 4 (8) ◽  
pp. 581-589 ◽  
Author(s):  
Yuan Fang ◽  
Xiaofen Mo ◽  
Wenyi Guo ◽  
Meng Zhang ◽  
Peihua Zhang ◽  
...  
Keyword(s):  
Optic Nerve ◽  
Schwann Cell ◽  
Nerve Regeneration ◽  
Adult Rats ◽  
Optic Nerve Regeneration ◽  
New Type

Y-P30 confers neuroprotection after optic nerve crush in adult rats

Neuroreport ◽  
2011 ◽  
Vol 22 (11) ◽  
pp. 544-547 ◽  
Author(s):  
Tamar Macharadze ◽  
Peter Landgraf ◽  
Hans-Christian Pape ◽  
Petra Wahle ◽  
Michael R. Kreutz
Keyword(s):  
Optic Nerve ◽  
Optic Nerve Crush ◽  
Adult Rats ◽  
Nerve Crush

scholarly journals Regional distribution, developmental changes, and cellular localization of CNTF-mRNA and protein in the rat brain.

1991 ◽  
Vol 115 (2) ◽  
pp. 447-459 ◽  
Author(s):  
K A Stöckli ◽  
L E Lillien ◽  
M Näher-Noé ◽  
G Breitfeld ◽  
R A Hughes ◽  
...  
Keyword(s):  
Optic Nerve ◽  
Olfactory Bulb ◽  
Cellular Localization ◽  
Time Course ◽  
Regional Distribution ◽  
Developmental Expression ◽  
Adult Rats

Ciliary neurotrophic factor (CNTF) is a potent survival molecule for a variety of embryonic neurons in culture. The developmental expression of CNTF occurs clearly after the time period of the physiological cell death of CNTF-responsive neurons. This, together with the sites of expression, excludes CNTF as a target-derived neuronal survival factor, at least in rodents. However, CNTF also participates in the induction of type 2 astrocyte differentiation in vitro. Here we demonstrate that the time course of the expression of CNTF-mRNA and protein in the rat optic nerve (as evaluated by quantitative Northern blot analysis and biological activity, respectively) is compatible with such a glial differentiation function of CNTF in vivo. We also show that the type 2 astrocyte-inducing activity previously demonstrated in optic nerve extract can be precipitated by an antiserum against CNTF. Immunohistochemical analysis of astrocytes in vitro and in vivo demonstrates that the expression of CNTF is confined to a subpopulation of type 1 astrocytes. The olfactory bulb of adult rats has comparably high levels of CNTF to the optic nerve, and here again, CNTF-immunoreactivity is localized in a subpopulation of astrocytes. However, the postnatal expression of CNTF in the olfactory bulb occurs later than in the optic nerve. In other brain regions both CNTF-mRNA and protein levels are much lower.

Delayed kindling epileptogenesis and increased neurogenesis in adult rats housed in an enriched environment

2002 ◽  
Vol 954 (2) ◽  
pp. 277-285 ◽  
Author(s):  
Romane Auvergne ◽  
Carole Leré ◽  
Bouchaı̈b El Bahh ◽  
Sébastien Arthaud ◽  
Véronique Lespinet ◽  
...  
Keyword(s):  
Enriched Environment ◽  
Adult Rats
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