scholarly journals Quality of Reporting and Adherence to ARRIVE Guidelines in Animal Studies for Chagas Disease Preclinical Drug Research: A Systematic Review

2015 ◽  
Vol 9 (11) ◽  
pp. e0004194 ◽  
Author(s):  
Julián Ernesto Nicolás Gulin ◽  
Daniela Marisa Rocco ◽  
Facundo García-Bournissen
Keyword(s):  
Systematic Review ◽  
Chagas Disease ◽  
Animal Studies ◽  
Drug Research ◽  
Quality Of Reporting

scholarly journals Quality of Reporting in Preclinical Urethral Tissue Engineering Studies: A Systematic Review to Assess Adherence to the ARRIVE Guidelines

Animals ◽  
2021 ◽  
Vol 11 (8) ◽  
pp. 2456
Author(s):  
Tariq O. Abbas ◽  
Abubakr Elawad ◽  
Abdul Kareem Pullattayil S. ◽  
Cristian Pablo Pennisi
Keyword(s):  
Systematic Review ◽  
Tissue Engineering ◽  
Animal Studies ◽  
Therapeutic Option ◽  
Laboratory Animals ◽  
Size Estimation ◽  
Ethical Guidelines ◽  
Preclinical Research ◽  
Quality Of Reporting

Preclinical research within the area of urethral tissue engineering has not yet been successfully translated into an efficient therapeutic option for patients. This gap could be attributed, in part, to inadequate design and reporting of the studies employing laboratory animals. In this study, a systematic review was conducted to investigate the quality of reporting in preclinical studies utilizing tissue engineering approaches for urethral repair. The scope was on studies performed in rabbits, published between January 2014 and March 2020. Quality assessment of the data was conducted according to the Animal Research: Reporting of in Vivo Experiments (ARRIVE) guidelines by the scoring of a 38-item checklist in different categories. A total of 28 articles that fulfilled the eligibility criteria were included in the study. The range of ARRIVE score was from 0 to 100, taking into consideration having reported the item in question or not. The mean checklist score was 53%. The items that attained the highest scores included the number of animals utilized, the size of control and experimental groups, and the definition of experimental outcomes. The least frequently reported items included the data regarding the experimental procedure, housing and husbandry, determination and justification of the number of animals, and reporting of adverse events. Surprisingly, full disclosure about ethical guidelines and animal protocol approval was missing in 54% of the studies. No paper stated the sample size estimation. Overall, our study found that a large number of studies display inadequate reporting of fundamental information and that the quality of reporting improved marginally over the study period. We encourage a comprehensive implementation of the ARRIVE guidelines in animal studies exploring tissue engineering for urethral repair, not only to facilitate effective translation of preclinical research findings into clinical therapies, but also to ensure compliance with ethical principles and to minimize unnecessary animal studies.

scholarly journals The quality of intervention reporting in trials of therapeutic exercise for hip osteoarthritis: a secondary analysis of a systematic review

Trials ◽  
2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Louise C. Burgess ◽  
Thomas W. Wainwright ◽  
Khara A. James ◽  
Johan von Heideken ◽  
Maura D. Iversen
Keyword(s):  
Systematic Review ◽  
Secondary Analysis ◽  
Internal Validity ◽  
Hip Osteoarthritis ◽  
Therapeutic Exercise ◽  
Quality Of Reporting ◽  
Effective Interventions ◽  
Randomised Controlled ◽  
Intervention Reporting

Abstract Background Therapeutic exercise is recommended as a core treatment for hip osteoarthritis (HOA). Whilst it is widely accepted that exercise can improve pain and disability, optimal type and dose of exercise are yet to be agreed upon. This may, in part, be attributed to the wide variation and inadequate reporting of interventions within the literature. This study evaluates the quality of intervention reporting among trials of therapeutic exercise in HOA. Methods Randomised controlled trials (RCTs) were sourced in a systematic review, completed in August 2020. Two raters independently used the Template for Intervention Description and Replication (TIDieR) and Consensus on Exercise Reporting Template (CERT) to evaluate intervention reporting. Correlations between quality assessment scores and CERT and TIDieR scores evaluated the relationship between internal validity and external applicability. The year of publication was compared to the quality of reporting scores. Results Fourteen RCTs were included in the analysis. On average, studies were awarded 9.43 ± 1.95 out of 12 points for the TIDieR checklist (range 4–12) and 13.57 ± 4.01 out of 19 points for the CERT (range 5–19). Pearson’s correlation coefficient suggested that the quality of reporting had improved over time and that there was a fair, positive relationship between internal validity and external applicability. Discussion Whilst the quality of intervention reporting is improving, many RCTs of therapeutic exercise in HOA lack the detail necessary to allow accurate evaluation and replication. Researchers are encouraged to utilise the standardised reporting guidelines to increase the translation of effective interventions into clinical practice.

scholarly journals Comparative efficacy of antimicrobial treatments in dairy cows at dry-off to prevent new intramammary infections during the dry period or clinical mastitis during early lactation: a systematic review and network meta-analysis

2019 ◽  
Vol 20 (2) ◽  
pp. 199-216 ◽  
Author(s):  
C. B. Winder ◽  
J. M. Sargeant ◽  
D. Hu ◽  
C. Wang ◽  
D. F. Kelton ◽  
...  
Keyword(s):  
Systematic Review ◽  
Dairy Cows ◽  
Meta Analysis ◽  
Clinical Mastitis ◽  
Comparative Efficacy ◽  
Dry Period ◽  
Quality Of Reporting ◽  
Intramammary Infections ◽  
Antimicrobial Treatments

AbstractA systematic review and network meta-analysis were conducted to assess the relative efficacy of antimicrobial therapy given to dairy cows at dry-off. Eligible studies were controlled trials assessing the use of antimicrobials compared to no treatment or an alternative treatment, and assessed one or more of the following outcomes: incidence of intramammary infection (IMI) at calving, incidence of IMI during the first 30 days in milk (DIM), or incidence of clinical mastitis during the first 30 DIM. Databases and conference proceedings were searched for relevant articles. The potential for bias was assessed using the Cochrane Risk of Bias 2.0 algorithm. From 3480 initially identified records, 45 trials had data extracted for one or more outcomes. Network meta-analysis was conducted for IMI at calving. The use of cephalosporins, cloxacillin, or penicillin with aminoglycoside significantly reduced the risk of new IMI at calving compared to non-treated controls (cephalosporins, RR = 0.37, 95% CI 0.23–0.65; cloxacillin, RR = 0.55, 95% CI 0.38–0.79; penicillin with aminoglycoside, RR = 0.42, 95% CI 0.26–0.72). Synthesis revealed challenges with a comparability of outcomes, replication of interventions, definitions of outcomes, and quality of reporting. The use of reporting guidelines, replication among interventions, and standardization of outcome definitions would increase the utility of primary research in this area.

scholarly journals Comparative efficacy of teat sealants given prepartum for prevention of intramammary infections and clinical mastitis: a systematic review and network meta-analysis

2019 ◽  
Vol 20 (2) ◽  
pp. 182-198 ◽  
Author(s):  
C. B. Winder ◽  
J. M. Sargeant ◽  
D. Hu ◽  
C. Wang ◽  
D. F. Kelton ◽  
...  
Keyword(s):  
Systematic Review ◽  
Meta Analysis ◽  
Clinical Mastitis ◽  
Risk Of Bias ◽  
Comparative Efficacy ◽  
Primary Research ◽  
Quality Of Reporting ◽  
Intramammary Infections ◽  
Bismuth Subnitrate

AbstractA systematic review and network meta-analysis were conducted to assess the relative efficacy of internal or external teat sealants given at dry-off in dairy cattle. Controlled trials were eligible if they assessed the use of internal or external teat sealants, with or without concurrent antimicrobial therapy, compared to no treatment or an alternative treatment, and measured one or more of the following outcomes: incidence of intramammary infection (IMI) at calving, IMI during the first 30 days in milk (DIM), or clinical mastitis during the first 30 DIM. Risk of bias was based on the Cochrane Risk of Bias 2.0 tool with modified signaling questions. From 2280 initially identified records, 32 trials had data extracted for one or more outcomes. Network meta-analysis was conducted for IMI at calving. Use of an internal teat sealant (bismuth subnitrate) significantly reduced the risk of new IMI at calving compared to non-treated controls (RR = 0.36, 95% CI 0.25–0.72). For comparisons between antimicrobial and teat sealant groups, concerns regarding precision were seen. Synthesis of the primary research identified important challenges related to the comparability of outcomes, replication and connection of interventions, and quality of reporting of study conduct.

Systematic Review as a Research Method in Library and Information Science

2020 ◽  
pp. 80-94 ◽  
Author(s):  
Mercy Mlay Komba ◽  
Edda Tandi Lwoga
Keyword(s):  
Systematic Review ◽  
Systematic Reviews ◽  
Research Method ◽  
Information Science ◽  
Library And Information Science ◽  
Knowledge Gaps ◽  
Quality Of Reporting ◽  
Research Teams ◽  
Current State

The aim of this chapter is to assess the current state of application of systematic reviews (SRs) in library and information science (LIS) field and determine how information scientists can advance the SRs as a methodology. The literature shows that there is an increasing number of SRs in LIS although there are still knowledge gaps about the use of SRs as a methodology. The quality of reporting in primary studies in LIS is still poor, and hence, it becomes difficult to appraise the value of the study undertaken. In order to advance the use of SRs in LIS domain, it is important to introduce SRs in LIS education curricular, integrate SRs as part of the continuing scientist development programmes (CPD), use automated SR software to minimize workload, introduce SRs a formal role and service in the libraries, collaborate with research teams as co-authors to conduct SRs not only in the topics defined by research teams, but also in LIS topics, and create SR databases and tools in LIS.

Quality of design and reporting of animal research in peritoneal dialysis: A scoping review

2020 ◽  
Vol 40 (4) ◽  
pp. 394-404
Author(s):  
Janusz Witowski ◽  
Dorota Sikorska ◽  
András Rudolf ◽  
Izabela Miechowicz ◽  
Julian Kamhieh-Milz ◽  
...  
Keyword(s):  
Peritoneal Dialysis ◽  
Scoping Review ◽  
Animal Studies ◽  
Reporting Quality ◽  
Animal Research ◽  
Size Estimation ◽  
Quality Of Reporting ◽  
The Impact

The concerns about reproducibility and validity of animal studies are partly related to poor experimental design and reporting. Here, we undertook a scoping review of the literature to determine the extent and quality of reporting of animal studies on peritoneal dialysis (PD). Online databases were searched to identify 567 relevant original articles published between 1979 and 2018. These were analyzed with respect to bibliographic parameters and general aspects of animal experimentation. A subgroup of 120 studies was analyzed in detail in terms of the impact on the reporting quality of the Animal Research: Reporting of In Vivo Experiments (ARRIVE) guidelines for animal studies. The number of animal studies on PD increased continuously over the years with a thematic shift toward long-term preservation of the peritoneum as a dialyzing organ. There were significant deficiencies in research design with the lack of sample size estimation, randomization, and blinding being the commonest shortcomings. The description of animal numbers, housing conditions, use of medication, and statistical analysis was incomplete. The introduction in 2010 of the ARRIVE guidelines produced very little improvement in the completeness of reporting regardless of journal impact factor. The animal studies on PD suffer from deficits in experimental protocols and transparent reporting. These drawbacks need to be corrected to ensure high-quality and much-needed animal research in PD.

Updated Method Guidelines for Cochrane Musculoskeletal Group Systematic Reviews and Metaanalyses

2013 ◽  
Vol 41 (2) ◽  
pp. 194-205 ◽  
Author(s):  
Elizabeth A.T. Ghogomu ◽  
Lara J. Maxwell ◽  
Rachelle Buchbinder ◽  
Tamara Rader ◽  
Jordi Pardo Pardo ◽  
...  
Keyword(s):  
Systematic Review ◽  
Systematic Reviews ◽  
Musculoskeletal Diseases ◽  
Cochrane Collaboration ◽  
Previous Method ◽  
Systematic Review Methodology ◽  
Quality Of Reporting ◽  
For Profit ◽  
Cochrane Reviews

The Cochrane Musculoskeletal Group (CMSG), one of 53 groups of the not-for-profit, international Cochrane Collaboration, prepares, maintains, and disseminates systematic reviews of treatments for musculoskeletal diseases. It is important that authors conducting CMSG reviews and the readers of our reviews be aware of and use updated, state-of-the-art systematic review methodology. One hundred sixty reviews have been published. Previous method guidelines for systematic reviews of interventions in the musculoskeletal field published in 2006 have been substantially updated to incorporate methodological advances that are mandatory or highly desirable in Cochrane reviews and knowledge translation advances. The methodological advances include new guidance on searching, new risk-of-bias assessment, grading the quality of the evidence, the new Summary of Findings table, and comparative effectiveness using network metaanalysis. Method guidelines specific to musculoskeletal disorders are provided by CMSG editors for various aspects of undertaking a systematic review. These method guidelines will help improve the quality of reporting and ensure high standards of conduct as well as consistency across CMSG reviews.

scholarly journals Quality of reporting randomized controlled trials (RCTs) in diabetes in Iran; a systematic review

2015 ◽  
Vol 15 (1) ◽  
Author(s):  
Faeze Gohari ◽  
Hamid Reza Baradaran ◽  
Morteza Tabatabaee ◽  
Shabnam Anijidani ◽  
Fatemeh Mohammadpour Touserkani ◽  
...  
Keyword(s):  
Systematic Review ◽  
Randomized Controlled Trials ◽  
Controlled Trials ◽  
Quality Of Reporting ◽  
Randomized Controlled
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