scholarly journals Use of Viremia to Evaluate the Baseline Case Fatality Ratio of Ebola Virus Disease and Inform Treatment Studies: A Retrospective Cohort Study

PLoS Medicine ◽  
2015 ◽  
Vol 12 (12) ◽  
pp. e1001908 ◽  
Author(s):  
Oumar Faye ◽  
Alessio Andronico ◽  
Ousmane Faye ◽  
Henrik Salje ◽  
Pierre-Yves Boëlle ◽  
...  
Keyword(s):  
Cohort Study ◽  
Retrospective Cohort Study ◽  
Retrospective Cohort ◽  
Ebola Virus ◽  
Virus Disease ◽  
Case Fatality ◽  
Ebola Virus Disease ◽  
Case Fatality Ratio ◽  
Baseline Case

G28 Ebola virus disease in children in Sierra Leone: A retrospective cohort study

2016 ◽  
Vol 101 (Suppl 1) ◽  
pp. A19.2-A21
Author(s):  
FC Fitzgerald ◽  
A Naveed ◽  
K Wing ◽  
M Gbessay ◽  
JCG Ross ◽  
...  
Keyword(s):  
Cohort Study ◽  
Sierra Leone ◽  
Retrospective Cohort Study ◽  
Retrospective Cohort ◽  
Ebola Virus ◽  
Virus Disease ◽  
Ebola Virus Disease

scholarly journals Subsequent mortality in survivors of Ebola virus disease in Guinea: a nationwide retrospective cohort study

2019 ◽  
Vol 19 (11) ◽  
pp. 1202-1208 ◽  
Author(s):  
Mory Keita ◽  
Boubacar Diallo ◽  
Samuel Mesfin ◽  
Abdourahmane Marega ◽  
Koumpingnin Yacouba Nebie ◽  
...  
Keyword(s):  
Cohort Study ◽  
Retrospective Cohort Study ◽  
Retrospective Cohort ◽  
Ebola Virus ◽  
Virus Disease ◽  
Ebola Virus Disease

scholarly journals Impact of Intravenous Fluid Therapy on Survival Among Patients With Ebola Virus Disease: An International Multisite Retrospective Cohort Study

2019 ◽  
Vol 70 (6) ◽  
pp. 1038-1047 ◽  
Author(s):  
Adam R Aluisio ◽  
Derrick Yam ◽  
Jillian L Peters ◽  
Daniel K Cho ◽  
Shiromi M Perera ◽  
...  
Keyword(s):  
Cohort Study ◽  
Propensity Score ◽  
Retrospective Cohort Study ◽  
Retrospective Cohort ◽  
Ebola Virus ◽  
Virus Disease ◽  
Intravenous Fluid ◽  
Ebola Virus Disease ◽  
Time Varying ◽  
Significant Difference

Abstract Background Intravenous fluid (IVF) is a frequently recommended intervention in Ebola virus disease (EVD), yet its impact on patient outcomes remains unclear. Methods This retrospective cohort study evaluated patients with EVD admitted to 5 Ebola treatment units (ETUs) in West Africa. The primary outcome was the difference in 28-day survival between cases treated and not treated with IVF. To control for demographic and clinical factors related to both IVF exposure and survival, cases were compared using propensity score matching. To control for time-varying patient and treatment factors over the course of ETU care, a marginal structural proportional hazards model (MSPHM) with inverse probability weighting was used to assess for 28-day survival differences. Results Among 424 EVD-positive cases with data for analysis, 354 (83.5%) were treated with IVF at some point during their ETU admission. Overall, 146 (41.3%) cases treated with IVF survived, whereas 31 (44.9%) cases not treated with any IVF survived (P = .583). Matched propensity score analysis found no significant difference in 28-day survival between cases treated and not treated with IVF during their first 24 and 48 hours of care. Adjusted MSPHM survival analyses also found no significant difference in 28-day survival for cases treated with IVF (27.3%) compared to those not treated with IVF (26.9%) during their entire ETU admission (P = .893). Conclusions After adjustment for patient- and treatment-specific time-varying factors, there was no significant difference in survival among patients with EVD treated with IVF as compared to those not treated with IVF.

scholarly journals Deaths, late deaths, and role of infecting dose in Ebola virus disease in Sierra Leone: retrospective cohort study

BMJ ◽  
2016 ◽  
pp. i2403 ◽  
Author(s):  
Hilary Bower ◽  
Elizabeth Smout ◽  
Mohamed S Bangura ◽  
Osman Kamara ◽  
Cecilia Turay ◽  
...  
Keyword(s):  
Cohort Study ◽  
Sierra Leone ◽  
Retrospective Cohort Study ◽  
Retrospective Cohort ◽  
Ebola Virus ◽  
Virus Disease ◽  
Ebola Virus Disease

scholarly journals Long-term sequelae after Ebola virus disease in Bundibugyo, Uganda: a retrospective cohort study

2015 ◽  
Vol 15 (8) ◽  
pp. 905-912 ◽  
Author(s):  
Danielle V Clark ◽  
Hannah Kibuuka ◽  
Monica Millard ◽  
Salim Wakabi ◽  
Luswa Lukwago ◽  
...  
Keyword(s):  
Cohort Study ◽  
Retrospective Cohort Study ◽  
Retrospective Cohort ◽  
Ebola Virus ◽  
Virus Disease ◽  
Ebola Virus Disease
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