scholarly journals Dissecting the Calcium-Induced Differentiation of Human Primary Keratinocytes Stem Cells by Integrative and Structural Network Analyses

2015 ◽  
Vol 11 (5) ◽  
pp. e1004256 ◽  
Author(s):  
Kiana Toufighi ◽  
Jae-Seong Yang ◽  
Nuno Miguel Luis ◽  
Salvador Aznar Benitah ◽  
Ben Lehner ◽  
...  
Keyword(s):  
Stem Cells ◽  
Primary Keratinocytes ◽  
Induced Differentiation ◽  
Network Analyses ◽  
Structural Network ◽  
Human Primary Keratinocytes

scholarly journals Wnt5a/β-Catenin Signaling Drives Calcium-Induced Differentiation of Human Primary Keratinocytes

2014 ◽  
Vol 134 (8) ◽  
pp. 2183-2191 ◽  
Author(s):  
Tanja Popp ◽  
Dirk Steinritz ◽  
Andreas Breit ◽  
Janina Deppe ◽  
Virginia Egea ◽  
...  
Keyword(s):  
Primary Keratinocytes ◽  
Induced Differentiation ◽  
Human Primary Keratinocytes

scholarly journals GATA3 regulates FLG and FLG2 expression in human primary keratinocytes

2017 ◽  
Vol 7 (1) ◽  
Author(s):  
Jana Zeitvogel ◽  
Neele Jokmin ◽  
Samira Rieker ◽  
Ilona Klug ◽  
Christina Brandenberger ◽  
...  
Keyword(s):  
Primary Keratinocytes ◽  
Human Primary Keratinocytes

scholarly journals Coupled Global and Targeted Proteomics of Human Embryonic Stem Cells during Induced Differentiation

2008 ◽  
Vol 7 (4) ◽  
pp. 750-767 ◽  
Author(s):  
Anastasia K. Yocum ◽  
Theresa E. Gratsch ◽  
Nancy Leff ◽  
John R. Strahler ◽  
Christie L. Hunter ◽  
...  
Keyword(s):  
Stem Cells ◽  
Embryonic Stem Cells ◽  
Human Embryonic Stem Cells ◽  
Embryonic Stem ◽  
Targeted Proteomics ◽  
Induced Differentiation

Isolation and culture of human primary keratinocytes – a methods review

2018 ◽  
Author(s):  
Aneta Ścieżyńska ◽  
Aleksandra Nogowska ◽  
Maria Sikorska ◽  
Justyna Konys ◽  
Anita Karpińska ◽  
...  
Keyword(s):  
Primary Keratinocytes ◽  
Human Primary Keratinocytes

scholarly journals Interferon-Lambda 1 Inhibits Staphylococcus aureus Colonization in Human Primary Keratinocytes

2021 ◽  
Vol 12 ◽  
Author(s):  
Xia Wu ◽  
Yan Zhao ◽  
Ying Gu ◽  
Kun Li ◽  
Xiaojie Wang ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Mrna Expression ◽  
Human Keratinocytes ◽  
Skin Lesions ◽  
Inhibitory Effect ◽  
Oxidase Inhibitor ◽  
Primary Keratinocytes ◽  
Intracellular Ros ◽  
Normal Human ◽  
Human Primary Keratinocytes

Atopic dermatitis (AD) is a common inflammatory skin disease. Staphylococcus aureus (S. aureus) colonization in skin lesions occurs in approximately 70% of AD patients. It has been found that IFN-λ1 can inhibit the colonization of S. aureus in normal human nasal mucosa. IFN-λ1 can increase IL-28RA in infected human keratinocytes. In this study, we found that IFN-λ1 can increase mRNA expression of FLG and antimicrobial peptides (AMPs) and inhibit TSLP mRNA expression in infected human keratinocytes. IFN-λ1 can increase intracellular ROS level, decrease STAT1 phosphorylation, and inhibit the colonization of S. aureus in human primary keratinocytes. These effects were attenuated by knocking-down IL-28R and NADPH oxidase inhibitor, suggesting that this function was mediated by JAK-STAT1 signaling pathway. These results suggest that IFN-λ1 might have an inhibitory effect on S. aureus colonization in AD lesions. Our findings might have potential value in the treatment for AD.

scholarly journals Nicotinamide Metabolism Modulates the Proliferation/Differentiation Balance and Senescence of Human Primary Keratinocytes

2019 ◽  
Vol 139 (8) ◽  
pp. 1638-1647.e3 ◽  
Author(s):  
Chye Ling Tan ◽  
Toby Chin ◽  
Christina Yan Ru Tan ◽  
Holly A. Rovito ◽  
Ling Shih Quek ◽  
...  
Keyword(s):  
Primary Keratinocytes ◽  
Human Primary Keratinocytes

scholarly journals Effects of anthrax lethal toxin on human primary keratinocytes

2008 ◽  
Vol 105 (6) ◽  
pp. 1756-1767 ◽  
Author(s):  
S.S. Koçer ◽  
M. Matic ◽  
M. Ingrassia ◽  
S.G. Walker ◽  
E. Roemer ◽  
...  
Keyword(s):  
Lethal Toxin ◽  
Anthrax Lethal Toxin ◽  
Primary Keratinocytes ◽  
Human Primary Keratinocytes
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