scholarly journals A Whole-Body Model for Glycogen Regulation Reveals a Critical Role for Substrate Cycling in Maintaining Blood Glucose Homeostasis

2011 ◽  
Vol 7 (12) ◽  
pp. e1002272 ◽  
Author(s):  
Ke Xu ◽  
Kevin T. Morgan ◽  
Abby Todd Gehris ◽  
Timothy C. Elston ◽  
Shawn M. Gomez
Keyword(s):  
Blood Glucose ◽  
Glucose Homeostasis ◽  
Critical Role ◽  
Whole Body ◽  
Body Model ◽  
Blood Glucose Homeostasis ◽  
Whole Body Model

scholarly journals Models for the Study of Whole-Body Glucose Kinetics: A Mathematical Synthesis

2013 ◽  
Vol 2013 ◽  
pp. 1-16 ◽  
Author(s):  
Leslie L. McKnight ◽  
Secundino Lopez ◽  
Anna Kate Shoveller ◽  
James France
Keyword(s):  
Mathematical Modeling ◽  
Blood Glucose ◽  
Glucose Metabolism ◽  
Glucose Homeostasis ◽  
Whole Body ◽  
Glucose Kinetics ◽  
Isotope Tracer ◽  
Glucose System ◽  
Blood Glucose Homeostasis

The maintenance of blood glucose homeostasis is complex and involves several key tissues. Most of these tissues are not easily accessible, making direct measurement of the physiological parameters involved in glucose metabolism difficult. The use of isotope tracer methodology and mathematical modeling allows indirect estimates of in vivo glucose metabolism through relatively noninvasive means. The purpose of this paper was to provide a mathematical synthesis of the models developed for describing glucose kinetics. As many of the models were developed using dogs, example data from the canine literature are presented. However, examples from the human and feline literature are also given in the absence of dog data. The glucose system is considered in both the steady and nonsteady states, and the models are examined by grouping them into schemes consisting of one, two, and three glucose compartments. Noncompartmental schemes are also considered briefly.

scholarly journals Weight-Independent Changes in Blood Glucose Homeostasis After Gastric Bypass or Vertical Sleeve Gastrectomy in Rats

2011 ◽  
Vol 141 (3) ◽  
pp. 950-958 ◽  
Author(s):  
Adam P. Chambers ◽  
Lene Jessen ◽  
Karen K. Ryan ◽  
Stephanie Sisley ◽  
Hilary E. Wilson–Pérez ◽  
...  
Keyword(s):  
Gastric Bypass ◽  
Sleeve Gastrectomy ◽  
Blood Glucose ◽  
Glucose Homeostasis ◽  
Vertical Sleeve Gastrectomy ◽  
Blood Glucose Homeostasis

Evanescent effects of hypo- and hyperglucagonemia on blood glucose homeostasis

Metabolism ◽  
1976 ◽  
Vol 25 (11) ◽  
pp. 1381-1383 ◽  
Author(s):  
Robert Sherwin ◽  
John Wahren ◽  
Philip Felig
Keyword(s):  
Blood Glucose ◽  
Glucose Homeostasis ◽  
Blood Glucose Homeostasis
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