It takes two to tango: Concerted protein translation and degradation necessary for synaptic scaling

Ana Luisa Carvalho; Dominique Fernandes

doi:10.1371/journal.pbio.3001448

It takes two to tango: Concerted protein translation and degradation necessary for synaptic scaling

PLoS Biology ◽

10.1371/journal.pbio.3001448 ◽

2021 ◽

Vol 19 (11) ◽

pp. e3001448

Author(s):

Ana Luisa Carvalho ◽

Dominique Fernandes

Keyword(s):

Protein Translation ◽

Synaptic Scaling

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Hypercapnia impairs protein translation by activating integrated stress response

10.1055/s-0037-1615334 ◽

2018 ◽

Author(s):

V Kryvenko ◽

W Seeger ◽

I Vadász

Keyword(s):

Stress Response ◽

Protein Translation ◽

Integrated Stress Response

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Faculty Opinions recommendation of Synaptic scaling in vitro and in vivo.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1001137.13304 ◽

2001 ◽

Author(s):

Kevan A Martin

Keyword(s):

Synaptic Scaling

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Faculty Opinions recommendation of Genetic screens and selections for small molecules based on a synthetic riboswitch that activates protein translation.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1011414.249669 ◽

2004 ◽

Author(s):

Blake R Peterson

Keyword(s):

Small Molecules ◽

Protein Translation ◽

Genetic Screens

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Faculty Opinions recommendation of S6K1- and betaTRCP-mediated degradation of PDCD4 promotes protein translation and cell growth.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1047973.505767 ◽

2006 ◽

Author(s):

Daniel Gallie

Keyword(s):

Cell Growth ◽

Protein Translation

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Faculty Opinions recommendation of Regulation of ABCG2 expression at the 3' untranslated region of its mRNA through modulation of transcript stability and protein translation by a putative microRNA in the S1 colon cancer cell line.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1157497.617672 ◽

2009 ◽

Author(s):

Deanna Kroetz ◽

Mike Baldwin

Keyword(s):

Colon Cancer ◽

Cell Line ◽

Cancer Cell ◽

Untranslated Region ◽

Cancer Cell Line ◽

Protein Translation ◽

Colon Cancer Cell Line ◽

Colon Cancer Cell ◽

Transcript Stability

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Faculty Opinions recommendation of An evolutionarily conserved mechanism for controlling the efficiency of protein translation.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.3045958.2826056 ◽

2010 ◽

Author(s):

Jeff Coller ◽

Wenqian Hu

Keyword(s):

Protein Translation ◽

Evolutionarily Conserved

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Faculty Opinions recommendation of Host microRNA regulation of human cytomegalovirus immediate early protein translation promotes viral latency.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.718299729.793492319 ◽

2014 ◽

Author(s):

Jim Smiley ◽

Mary D Schneider

Keyword(s):

Human Cytomegalovirus ◽

Viral Latency ◽

Protein Translation ◽

Immediate Early ◽

Microrna Regulation ◽

Early Protein

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Faculty Opinions recommendation of Calcineurin mediates synaptic scaling via synaptic trafficking of Ca2+-permeable AMPA receptors.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.718475478.793499404 ◽

2014 ◽

Author(s):

Johannes Hell

Keyword(s):

Ampa Receptors ◽

Synaptic Scaling

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Faculty Opinions recommendation of Activity-dependent synaptic GRIP1 accumulation drives synaptic scaling up in response to action potential blockade.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.725587193.793542884 ◽

2018 ◽

Author(s):

Johannes Hell

Keyword(s):

Action Potential ◽

Scaling Up ◽

Synaptic Scaling ◽

Activity Dependent

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Faculty Opinions recommendation of Enterovirus-induced miR-141 contributes to shutoff of host protein translation by targeting the translation initiation factor eIF4E.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.7988956.10023054 ◽

2011 ◽

Author(s):

Lynne Maquat ◽

Olaf Isken

Keyword(s):

Translation Initiation ◽

Protein Translation ◽

Translation Initiation Factor ◽

Host Protein ◽

Initiation Factor

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