scholarly journals Twenty steps to ingrain power asymmetry in global health biomedical research

PLoS Biology ◽  
2021 ◽  
Vol 19 (9) ◽  
pp. e3001411
Author(s):  
Iruka N. Okeke
Keyword(s):  
Global Health ◽  
Biomedical Research ◽  
Power Asymmetry

From Ebola to COVID-19: what explains institutionalized manias and the ultimate preference for non-optimal solutions in global health governance?

2021 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Frederick Ahen
Keyword(s):  
Global Health ◽  
Health Inequalities ◽  
Developing Economies ◽  
Global Health Governance ◽  
Strategic Choices ◽  
Health Governance ◽  
Power Asymmetry ◽  
Content Type ◽  
Historical Perspectives ◽  
Multidisciplinary Study

Purpose The purpose of this paper is to investigate how “manias” in global health governance lead to health inequalities even before, during and in the aftermath of acute health crises such as the COVID-19 pandemic. “Manias” as used here refer to obsessive ir/rational behaviors, misguided policy/strategic choices and the exercise of power that benefit the major global health actors at the expense of stakeholders. Design/methodology/approach From post-colonial and historical perspectives, this study delineates how the major global health actors influence outcomes in global health governance and international business when they interact at the national–global level using an illustration from an emerging economy. Findings Power asymmetry in global health governance is constructed around the centralization of economic influence, medico-techno-scientific innovation and the geopolitical hegemony of a conglomerate of super-rich/powerful actors. They cluster these powers and resources in the core region (industrialized economies) and use them to influence the periphery (developing economies) through international NGOs, hybrid organizations, MNCs and multilateral/bilateral agreements. The power of actors to maintain manias lies in not only how they influence the periphery but also the consequences of the periphery’s “passivity” and “voluntary” renunciation of sovereignty in medical innovations and global health policies/politics. Social implications As a quintessential feature of manias, power asymmetry makes it harder for weaker actors to actually change the institutional conditions that produce structural inequalities in global health. Originality/value This timely and multidisciplinary study calls for a novel architecture of global health governance. Thus, democratizing global health governance with sufficiently foresighted investments that prioritize equitable access by and the inclusiveness of vulnerable stakeholders will help dismantle institutionalized manias while decreasing health inequalities.

scholarly journals The review of pre-exposure prophylaxis (PreP) for HIV prevention

2014 ◽  
Vol 11 (1) ◽  
pp. 50-59
Author(s):  
Meriam Caboral Stevens ◽  
Godfrey Aneke ◽  
Andrew Neplock
Keyword(s):  
Hiv Prevention ◽  
Global Health ◽  
Hiv Infection ◽  
Condom Use ◽  
Biomedical Research ◽  
Prevention Strategies ◽  
Global Health Issue ◽  
Exposure Prophylaxis ◽  
Current Guidelines ◽  
Prevention Of Hiv

Human lmmunodeficiency Virus (HlV) epidemic continues to represent a major global health issue. Today, there are several tools available to prevent the spread of HIV infection. However, there are several constraints to the current prevention strategies including low condom use, low acceptance of testing, low awareness of vulnerability and more emphasis on treatment. Prevention strategy is redirected towards reducing acquisition of HIV. Pre-exposure prophylaxis or PrEP is the latest groundbreaking innovation in biomedical research in the prevention of HIV transmission.The purpose of this paper is to review preex ding the current guidelines in the use of PreP.

scholarly journals Grand Challenges in Global Health: Engaging Civil Society Organizations in Biomedical Research in Developing Countries

PLoS Medicine ◽  
2007 ◽  
Vol 4 (9) ◽  
pp. e272 ◽  
Author(s):  
Anant Bhan ◽  
Jerome A Singh ◽  
Ross E. G Upshur ◽  
Peter A Singer ◽  
Abdallah S Daar
Keyword(s):  
Developing Countries ◽  
Civil Society ◽  
Global Health ◽  
Biomedical Research ◽  
Civil Society Organizations ◽  
Grand Challenges

Targeting Viral RNA-Dependent RNA Polymerases as an Antiviral Therapy

2021 ◽  
Vol 28 ◽  
Author(s):  
Daniel Miranda ◽  
David Jesse Sanchez
Keyword(s):  
Clinical Trials ◽  
Global Health ◽  
Rna Polymerase ◽  
Biomedical Research ◽  
Rna Viruses ◽  
Standard Of Care ◽  
Rna Dependent Rna Polymerase ◽  
Viral Pathogens ◽  
Relevant Topic ◽  
Target Rna

Abstract: Progressive globalization of our society brings not only worldwide integration, it increases and promotes our exposure to new viral pathogens with evident impacts on our global health. Especially with the emergence of SARS-CoV-2, our biomedical research infrastructure has never been more compelled to rapidly develop antiviral regimens that demonstrate improved efficacy against these pathogens. Here we showcase 3 poignant antivirals against the lucrative target, RNA-dependent RNA polymerase (RdRP) of RNA viruses – a timely and relevant topic given the present efforts against COVID-19. While effective drug designs against RdRP are important, their benefit and potential as a standard of care truly relies on them standing out in well-designed clinical trials.

Applications of Scanning Microscopy in Biomedical Research

1968 ◽  
Vol 26 ◽  
pp. 354-355
Author(s):  
T. L. Hayes
Keyword(s):  
Information Content ◽  
Biomedical Research ◽  
Biomedical Applications ◽  
Three Dimensional ◽  
Dental Enamel ◽  
Resolving Power ◽  
Whole Mount ◽  
Two Parameters ◽  
Content Information ◽  
Sectioned Tissue

Biomedical applications of the scanning electron microscope (SEM) have increased in number quite rapidly over the last several years. Studies have been made of cells, whole mount tissue, sectioned tissue, particles, human chromosomes, microorganisms, dental enamel and skeletal material. Many of the advantages of using this instrument for such investigations come from its ability to produce images that are high in information content. Information about the chemical make-up of the specimen, its electrical properties and its three dimensional architecture all may be represented in such images. Since the biological system is distinctive in its chemistry and often spatially scaled to the resolving power of the SEM, these images are particularly useful in biomedical research.In any form of microscopy there are two parameters that together determine the usefulness of the image. One parameter is the size of the volume being studied or resolving power of the instrument and the other is the amount of information about this volume that is displayed in the image. Both parameters are important in describing the performance of a microscope. The light microscope image, for example, is rich in information content (chemical, spatial, living specimen, etc.) but is very limited in resolving power.

Ultrastructure and analytical microprobe analysis of simian lung mite pigments

1986 ◽  
Vol 44 ◽  
pp. 324-325
Author(s):  
R. W. Cole ◽  
J. C. Kim
Keyword(s):  
Biomedical Research ◽  
Tissue Damage ◽  
Microprobe Analysis ◽  
Old World Monkeys ◽  
Old World ◽  
Experimental Animals ◽  
The Past ◽  
Lung Mite ◽  
Mite Infestations ◽  
Cardiopulmonary System

In recent years, non-human primates have become indispensable as experimental animals in many fields of biomedical research. Pharmaceutical and related industries alone use about 2000,000 primates a year. Respiratory mite infestations in lungs of old world monkeys are of particular concern because the resulting tissue damage can directly effect experimental results, especially in those studies involving the cardiopulmonary system. There has been increasing documentation of primate parasitology in the past twenty years.

Plant Medicines Key to Global Health

2011 ◽  
pp. 061611145657
Author(s):  
Geoffrey Cordell
Keyword(s):  
Global Health
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