scholarly journals Regulation plays a multifaceted role in the retention of gene duplicates

PLoS Biology ◽  
2019 ◽  
Vol 17 (11) ◽  
pp. e3000519 ◽  
Author(s):  
Johan Hallin ◽  
Christian R. Landry
Keyword(s):  
Gene Duplicates

scholarly journals Vertebrate SLRP family evolution and the subfunctionalization of osteoglycin gene duplicates in teleost fish

2018 ◽  
Vol 18 (1) ◽  
Author(s):  
R. A. Costa ◽  
R. S. T. Martins ◽  
E. Capilla ◽  
L. Anjos ◽  
D. M. Power
Keyword(s):  
Teleost Fish ◽  
Gene Duplicates

Expression ofsox11 gene duplicates in zebrafish suggests the reciprocal loss of ancestral gene expression patterns in development

2000 ◽  
Vol 217 (3) ◽  
pp. 279-292 ◽  
Author(s):  
Sara De Martino ◽  
Yi-Lin Yan ◽  
Trevor Jowett ◽  
John H. Postlethwait ◽  
Zoltan M. Varga ◽  
...  
Keyword(s):  
Gene Expression ◽  
Expression Patterns ◽  
Gene Expression Patterns ◽  
Ancestral Gene ◽  
Gene Duplicates

scholarly journals The evolution of gene duplicates in angiosperms and the impact of protein-protein interactions and the mechanism of duplication

2019 ◽  
Author(s):  
Jonas Defoort ◽  
Yves Van de Peer ◽  
Lorenzo Carretero-Paulet
Keyword(s):  
Protein Interactions ◽  
Specific Property ◽  
Small Scale ◽  
Biological Interactions ◽  
Protein Protein Interactions ◽  
Protein Protein Interaction ◽  
Functional Dynamics ◽  
Dosage Balance ◽  
Gene Duplicates ◽  
The Impact

Abstract Gene duplicates, generated either through whole genome duplication (WGD) or small-scale duplication (SSD), are prominent in angiosperms and are believed to play an important role in adaptation and in generating evolutionary novelty. Previous studies reported contrasting evolutionary and functional dynamics of duplicate genes depending on the mechanism of origin, a behaviour that is hypothesized to stem from constraints to maintain the relative dosage balance between the genes concerned and their interaction context. However, the mechanisms ultimately influencing loss and retention of gene duplicates over evolutionary time are not yet fully elucidated. Here, by using a robust classification of gene duplicates in Arabidopsis thaliana, Solanum lycopersicum and Zea mays, large RNAseq expression compendia and an extensive protein-protein interaction (PPI) network from Arabidopsis, we investigated the impact of PPIs on the differential evolutionary and functional fate of WGD and SSD duplicates. In all three species, retained WGD duplicates show stronger constraints to diverge at the sequence and expression level than SSD ones, a pattern that is also observed for shared PPI partners between Arabidopsis duplicates. PPIs are preferentially distributed among WGD duplicates and specific functional categories. Furthermore, duplicates with PPIs tend to be under stronger constraints to evolve than their counterparts without PPIs regardless of their mechanism of origin. Our results support dosage balance constraint as a specific property of genes involved in biological interactions, including physical PPIs, and suggest that additional factors may be differently influencing the evolution of genes following duplication, depending on the species, time and mechanism of origin.

Experimental Evolution of Gene Duplicates in a Bacterial Plasmid Model

2007 ◽  
Vol 64 (2) ◽  
pp. 215-222 ◽  
Author(s):  
Alisha K. Holloway ◽  
Timothy Palzkill ◽  
James J. Bull
Keyword(s):  
Experimental Evolution ◽  
Bacterial Plasmid ◽  
Gene Duplicates
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