scholarly journals Different Paths, Same Structure: “Developmental Systems Drift” at Work

PLoS Biology ◽  
2011 ◽  
Vol 9 (7) ◽  
pp. e1001113 ◽  
Author(s):  
Richard Robinson
Keyword(s):  
Developmental Systems ◽  
Developmental Systems Drift

Developmental Systems Drift and the Drivers of Sex Chromosome Evolution

2019 ◽  
Vol 37 (3) ◽  
pp. 799-810 ◽  
Author(s):  
Caroline M S Cauret ◽  
Marie-Theres Gansauge ◽  
Andrew S Tupper ◽  
Benjamin L S Furman ◽  
Martin Knytl ◽  
...  
Keyword(s):  
Sex Chromosomes ◽  
Sex Chromosome ◽  
Purifying Selection ◽  
W Chromosome ◽  
Developmental Systems ◽  
Recombination Suppression ◽  
Evolutionary Origins ◽  
Evolutionary Context ◽  
Genomic Locations ◽  
Developmental Systems Drift

Abstract Phenotypic invariance—the outcome of purifying selection—is a hallmark of biological importance. However, invariant phenotypes might be controlled by diverged genetic systems in different species. Here, we explore how an important and invariant phenotype—the development of sexually differentiated individuals—is controlled in over two dozen species in the frog family Pipidae. We uncovered evidence in different species for 1) an ancestral W chromosome that is not found in many females and is found in some males, 2) independent losses and 3) autosomal segregation of this W chromosome, 4) changes in male versus female heterogamy, and 5) substantial variation among species in recombination suppression on sex chromosomes. We further provide evidence of, and evolutionary context for, the origins of at least seven distinct systems for regulating sex determination among three closely related genera. These systems are distinct in their genomic locations, evolutionary origins, and/or male versus female heterogamy. Our findings demonstrate that the developmental control of sexual differentiation changed via loss, sidelining, and empowerment of a mechanistically influential gene, and offer insights into novel factors that impinge on the diverse evolutionary fates of sex chromosomes.

Erratum to: Developmental systems drift and the drivers of sex chromosome evolution

2020 ◽  
Vol 37 (6) ◽  
pp. 1844-1844
Author(s):  
Caroline M S Cauret ◽  
Marie-Theres Gansauge ◽  
Andrew S Tupper ◽  
Benjamin L S Furman ◽  
Martin Knytl ◽  
...  
Keyword(s):  
Chromosome Evolution ◽  
Sex Chromosome ◽  
Sex Chromosome Evolution ◽  
Developmental Systems ◽  
Developmental Systems Drift

scholarly journals Heterochronic shifts and conserved embryonic shape underlie crocodylian craniofacial disparity and convergence

2019 ◽  
Vol 286 (1897) ◽  
pp. 20182389 ◽  
Author(s):  
Zachary S. Morris ◽  
Kent A. Vliet ◽  
Arhat Abzhanov ◽  
Stephanie E. Pierce
Keyword(s):  
Ancestral State ◽  
Developmental Systems ◽  
Developmental Processes ◽  
Ontogenetic Trajectories ◽  
Evolutionary Context ◽  
Dietary Ecology ◽  
Direct Growth ◽  
Ontogenetic Allometry ◽  
Embryonic Region ◽  
Developmental Systems Drift

The distinctive anatomy of the crocodylian skull is intimately linked with dietary ecology, resulting in repeated convergence on blunt- and slender-snouted ecomorphs. These evolutionary shifts depend upon modifications of the developmental processes which direct growth and morphogenesis. Here we examine the evolution of cranial ontogenetic trajectories to shed light on the mechanisms underlying convergent snout evolution. We use geometric morphometrics to quantify skeletogenesis in an evolutionary context and reconstruct ancestral patterns of ontogenetic allometry to understand the developmental drivers of craniofacial diversity within Crocodylia. Our analyses uncovered a conserved embryonic region of morphospace (CER) shared by all non-gavialid crocodylians regardless of their eventual adult ecomorph. This observation suggests the presence of conserved developmental processes during early development (before Ferguson stage 20) across most of Crocodylia. Ancestral state reconstruction of ontogenetic trajectories revealed heterochrony, developmental constraint, and developmental systems drift have all played essential roles in the evolution of ecomorphs. Based on these observations, we conclude that two separate, but interconnected, developmental programmes controlling craniofacial morphogenesis and growth enabled the evolutionary plasticity of skull shape in crocodylians.

scholarly journals Variable levels of drift in tunicate cardiopharyngeal gene regulatory elements

EvoDevo ◽  
2019 ◽  
Vol 10 (1) ◽  
Author(s):  
William Colgan ◽  
Alexis Leanza ◽  
Ariel Hwang ◽  
Melissa B. DeBiasse ◽  
Isabel Llosa ◽  
...  
Keyword(s):  
Gene Regulatory Networks ◽  
Binding Sites ◽  
Regulatory Network ◽  
Network Architecture ◽  
Regulatory Networks ◽  
Regulatory Elements ◽  
Structural Constraints ◽  
Developmental Systems ◽  
Gene Regulatory ◽  
Developmental Systems Drift

Abstract Background Mutations in gene regulatory networks often lead to genetic divergence without impacting gene expression or developmental patterning. The rules governing this process of developmental systems drift, including the variable impact of selective constraints on different nodes in a gene regulatory network, remain poorly delineated. Results Here we examine developmental systems drift within the cardiopharyngeal gene regulatory networks of two tunicate species, Corella inflata and Ciona robusta. Cross-species analysis of regulatory elements suggests that trans-regulatory architecture is largely conserved between these highly divergent species. In contrast, cis-regulatory elements within this network exhibit distinct levels of conservation. In particular, while most of the regulatory elements we analyzed showed extensive rearrangements of functional binding sites, the enhancer for the cardiopharyngeal transcription factor FoxF is remarkably well-conserved. Even minor alterations in spacing between binding sites lead to loss of FoxF enhancer function, suggesting that bound trans-factors form position-dependent complexes. Conclusions Our findings reveal heterogeneous levels of divergence across cardiopharyngeal cis-regulatory elements. These distinct levels of divergence presumably reflect constraints that are not clearly associated with gene function or position within the regulatory network. Thus, levels of cis-regulatory divergence or drift appear to be governed by distinct structural constraints that will be difficult to predict based on network architecture.

A Developmental Psychopathology Perspective on Substance Use

2018 ◽  
Author(s):  
Dante Cicchetti ◽  
Fred A. Rogosch
Keyword(s):  
Substance Abuse ◽  
Substance Use ◽  
Child Maltreatment ◽  
Developmental Psychopathology ◽  
Developmental Tasks ◽  
Developmental Systems ◽  
Developmental Processes ◽  
Substance Use And Abuse ◽  
Successful Resolution

In this chapter, a developmental psychopathology conceptualization of child maltreatment is presented as an overarching heuristic with relevance for understanding the development of alcohol and substance use and abuse. This chapter also provides illustrations from research on how child maltreatment contributes to problem substance use in adolescence. Child maltreatment represents an extreme failure of the caregiving environment to provide many of the expectable experiences necessary to facilitate normal developmental processes. Maltreatment ushers in a probabilistic epigenesis for children characterized by an increased likelihood of failure and disruption in the successful resolution of major developmental tasks. These repeated disruptions lead to compromised developmental organizations of diverse developmental systems that increase the probability of the emergence of maladaptation, psychopathology, and substance abuse as negative transactions between the child and the environment ensue. Person-centered personality organizations and genetic moderation of maltreatment risk on substance use outcomes are also highlighted.

scholarly journals Bifurcation and chaos analysis for a discrete ecological developmental systems

2021 ◽  
Author(s):  
Xiao-Wei Jiang ◽  
Chaoyang Chen ◽  
Xian-He Zhang ◽  
Ming Chi ◽  
Huaicheng Yan
Keyword(s):  
Developmental Systems ◽  
Bifurcation And Chaos ◽  
Chaos Analysis
Sign in / Sign up

Export Citation Format

Share Document