scholarly journals A New Yeast Poly(A) Polymerase Complex Involved in RNA Quality Control

PLoS Biology ◽  
2005 ◽  
Vol 3 (6) ◽  
pp. e189 ◽  
Author(s):  
Štěpánka Vaňáčová ◽  
Jeannette Wolf ◽  
Georges Martin ◽  
Diana Blank ◽  
Sabine Dettwiler ◽  
...  
Keyword(s):  
Quality Control ◽  
Polymerase Complex ◽  
Rna Quality ◽  
Rna Quality Control ◽  
New Yeast

microRNA in erythrocytes

2010 ◽  
Vol 38 (1) ◽  
pp. 229-231 ◽  
Author(s):  
Andrew J. Hamilton
Keyword(s):  
Quality Control ◽  
Recent Work ◽  
Total Content ◽  
Human Erythrocytes ◽  
Rna Quality ◽  
Rna Quality Control ◽  
Non Coding Rnas ◽  
Low Levels ◽  
External Signals

Mammalian erythrocytes are generally thought to lack RNA and therefore to be unable to translate new proteins in response to internal or external signals. Support for this long-standing view has accumulated from diverse studies, most of which have focused on the total content of RNA or the overall level of translation. However, more recent work on specific types of RNA has shown the presence in human erythrocytes of both Y RNA and microRNA. The latter seem particularly incongruous given that their normal role is to attenuate the translation of mRNA. Y RNA binds the Ro autoantigen which may have a role in cellular RNA quality control. Therefore the presence of both of these non-coding RNAs indicates the possible existence of other cryptic RNAs in erythrocytes. It also suggests either the existence of low levels of translation or new uncharacterized processes involving microRNA in these cells.

scholarly journals Integrity of SRP RNA is ensured by La and the nuclear RNA quality control machinery

2014 ◽  
Vol 42 (16) ◽  
pp. 10698-10710 ◽  
Author(s):  
Eileen Leung ◽  
Claudia Schneider ◽  
Fu Yan ◽  
Hatem Mohi-El-Din ◽  
Grzegorz Kudla ◽  
...  
Keyword(s):  
Quality Control ◽  
Rna Quality ◽  
Nuclear Rna ◽  
Rna Quality Control ◽  
Srp Rna

scholarly journals Ribosome states signal RNA quality control

2021 ◽  
Vol 81 (7) ◽  
pp. 1372-1383 ◽  
Author(s):  
Karole N. D’Orazio ◽  
Rachel Green
Keyword(s):  
Quality Control ◽  
Rna Quality ◽  
Rna Quality Control

scholarly journals The RNA quality control pathway nonsense-mediated mRNA decay targets cellular and viral RNAs to restrict KSHV

2020 ◽  
Vol 11 (1) ◽  
Author(s):  
Yang Zhao ◽  
Xiang Ye ◽  
Myriam Shehata ◽  
William Dunker ◽  
Zhihang Xie ◽  
...  
Keyword(s):  
Quality Control ◽  
Mrna Decay ◽  
Viral Rnas ◽  
Rna Quality ◽  
Rna Quality Control ◽  
Nonsense Mediated Mrna Decay

NMD-Based Gene Regulation—A Strategy for Fitness Enhancement in Plants?

2019 ◽  
Vol 60 (9) ◽  
pp. 1953-1960 ◽  
Author(s):  
Misato Ohtani ◽  
Andreas Wachter
Keyword(s):  
Quality Control ◽  
Gene Regulation ◽  
Current Knowledge ◽  
Qualitative And Quantitative ◽  
Rna Quality ◽  
Quantitative Level ◽  
Splicing Variants ◽  
Rna Quality Control ◽  
Nonsense Mediated Mrna Decay ◽  
Environmental Responses

Abstract Post-transcriptional RNA quality control is a vital issue for all eukaryotes to secure accurate gene expression, both on a qualitative and quantitative level. Among the different mechanisms, nonsense-mediated mRNA decay (NMD) is an essential surveillance system that triggers degradation of both aberrant and physiological transcripts. By targeting a substantial fraction of all transcripts for degradation, including many alternative splicing variants, NMD has a major impact on shaping transcriptomes. Recent progress on the transcriptome-wide profiling and physiological analyses of NMD-deficient plant mutants revealed crucial roles for NMD in gene regulation and environmental responses. In this review, we will briefly summarize our current knowledge of the recognition and degradation of NMD targets, followed by an account of NMD’s regulation and physiological functions. We will specifically discuss plant-specific aspects of RNA quality control and its functional contribution to the fitness and environmental responses of plants.

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