Three Dimensional Imaging in Age-Related Macular Degeneration

2001 ◽  
Author(s):  
Masahiro Miura ◽  
Ann E. Eisner
Keyword(s):  
Macular Degeneration ◽  
Three Dimensional ◽  
Age Related Macular Degeneration ◽  
Three Dimensional Imaging ◽  
Age Related

Plexus-specific retinal capillary avascular area in exudative age-related macular degeneration with projection-resolved OCT angiography

2020 ◽  
pp. bjophthalmol-2020-317562
Author(s):  
Liqin Gao ◽  
Jie Wang ◽  
Qisheng You ◽  
Yukun Guo ◽  
Christina J Flaxel ◽  
...  
Keyword(s):  
Macular Degeneration ◽  
Three Dimensional ◽  
Age Related Macular Degeneration ◽  
Retinal Layer ◽  
Cross Sectional ◽  
Avascular Area ◽  
Age Related ◽  
Significant Difference ◽  
Retinal Capillary ◽  
Capillary Plexus

ObjectiveTo detect the plexus-specific retinal capillary avascular area in exudative age-related macular degeneration (EAMD) with projection-resolved optical coherence tomography angiography (PR-OCTA).Methods and analysisIn this prospective cross-sectional single centre study, eyes with treatment-naïve EAMD underwent macular 3×3 mm OCTA with AngioVue system. OCTA scans were analysed and processed including three-dimensional projection artefact removal, retinal layer semi-automated segmentation and en face angiogram generation. Automated quantification of extrafoveal (excluding the central 1 mm circle) avascular area (EAA) were calculated on projection-resolved superficial vascular complex (SVC), intermediate capillary plexus (ICP) and deep capillary plexus (DCP), respectively.ResultsNineteen eyes with EAMD and 19 age-matched healthy control eyes were included. There was no significant difference between the EAMD and control eyes in terms of age, sex, axial length and mean ocular perfusion pressure (all p>0.05). Compared with control eyes, EAMD eyes had significantly larger EAA in SVC (median 0.125 vs 0.059 mm2, p=0.006), ICP (0.016 vs 0.000 mm2, p=0.004) and DCP (0.033 vs 0.000 mm2, p＜0.001).ConclusionPR-OCTA showed that EAMD is associated with focal avascular area in all the three retinal vascular plexuses.

scholarly journals Distinguishing wet from dry age-related macular degeneration using three-dimensional computer-automated threshold Amsler grid testing

2011 ◽  
Vol 95 (10) ◽  
pp. 1419-1423 ◽  
Author(s):  
C. D. Robison ◽  
R. V. Jivrajka ◽  
S. R. Bababeygy ◽  
W. Fink ◽  
A. A. Sadun ◽  
...  
Keyword(s):  
Macular Degeneration ◽  
Three Dimensional ◽  
Age Related Macular Degeneration ◽  
Age Related ◽  
Amsler Grid
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