Micromachined Silicon Acoustic Delay Lines with 3D Printed Micro Linker Structures for Real-Time Photoacoustic Tomography

2016 ◽  
Author(s):  
Young Cho ◽  
Akhil Kumar ◽  
Song Xu ◽  
Jun Zou
Keyword(s):  
Real Time ◽  
Photoacoustic Tomography ◽  
Delay Lines ◽  
3D Printed

A 3D-printed Microfluidic System for Automated and Near Real-time Quantitation of Biofilm-induced indole

2019 ◽  
Author(s):  
Giraso Kabandana ◽  
Curtis G. Jones ◽  
Sahra Khan Sharifi ◽  
Chengpeng Chen
Keyword(s):  
Real Time ◽  
Release Kinetics ◽  
Microfluidic System ◽  
3D Printed

We developed a novel microfluidic system that enables automated and near real-time quantitation of indole release kinetics from biofilms.

3D printed permeation module to monitor interaction of cell membrane transporters with exogenic compounds in real-time

2021 ◽  
Vol 1153 ◽  
pp. 338296
Author(s):  
Hana Sklenářová ◽  
Michaela Rosecká ◽  
Burkhard Horstkotte ◽  
Petr Pávek ◽  
Manuel Miró ◽  
...  
Keyword(s):  
Cell Membrane ◽  
Real Time ◽  
Membrane Transporters ◽  
3D Printed

In situ real time defect detection of 3D printed parts

2017 ◽  
Vol 17 ◽  
pp. 135-142 ◽  
Author(s):  
Oliver Holzmond ◽  
Xiaodong Li
Keyword(s):  
Real Time ◽  
Defect Detection ◽  
3D Printed

scholarly journals Time Resolution Improvement Using Dual Delay Lines for Field-Programmable-Gate-Array-Based Time-to-Digital Converters with Real-Time Calibration

2018 ◽  
Vol 9 (1) ◽  
pp. 20 ◽  
Author(s):  
Yuan-Ho Chen
Keyword(s):  
Real Time ◽  
Field Programmable Gate Array ◽  
Delay Lines ◽  
Differential Nonlinearity ◽  
Time Calibration ◽  
Integral Nonlinearity ◽  
Resolution Improvement ◽  
Field Programmable ◽  
Gate Array ◽  
Set Up

This paper presents a time-to-digital converter (TDC) based on a field programmable gate array (FPGA) with a tapped delay line (TDL) architecture. This converter employs dual delay lines (DDLs) to enable real-time calibrations, and the proposed DDL-TDC measures the statistical distribution of delays to permit the calibration of nonuniform delay cells in FPGA-based TDC designs. DDLs are also used to set up alternate calibrations, thus enabling environmental effects to be immediately accounted for. Experimental results revealed that relative to a conventional TDL-TDC, the proposed DDL-TDC reduced the maximum differential nonlinearity by 26% and the integral nonlinearity by 30%. A root-mean-squared value of 32 ps was measured by inputting the constant delay source into the proposed DDL-TDC. The proposed scheme also maintained excellent linearity across a range of temperatures.

A Sample-to-Answer Compact Optical System for On-Site Detection of Candidatus Liberibacter Asiaticus

2021 ◽  
Vol 64 (1) ◽  
pp. 95-102
Author(s):  
Cui Wu ◽  
Zhen Wang ◽  
Hui Wu ◽  
Zhan Lu ◽  
Cheng Qian ◽  
...  
Keyword(s):  
Low Temperature ◽  
Real Time ◽  
Optical System ◽  
Power Supply ◽  
Integrated System ◽  
Candidatus Liberibacter Asiaticus ◽  
Field Detection ◽  
Candidatus Liberibacter ◽  
3D Printed ◽  
Liberibacter Asiaticus

HighlightsA portable system based on real-time fluorescence analysis was developed for field detection of Candidatus Liberibacter asiaticus within 40 min from sample to answer.A smartphone-assisted device was designed for easy operation, reliable nucleic acid amplification, and highly sensitive fluorescence detection, with sensitivity comparable to that of a commercial instrument.A novel homemade 3D printed box was used for in-field reagent storage, and it could maintain low temperature (<4°C) for about 8 hours without power supply.This fully integrated system is stable, easy to use, inexpensive, and has great application prospects in resource-limited areas.Abstract. Candidatus Liberibacter asiaticus (Las) is a main causal agent of huanglongbing (HLB), a destructive disease that has greatly reduced citrus yields and quality. Instruments with high sensitivity and portability are urgently required for on-site testing. In this study, a novel sample-to-answer optical system for on-site detection of Las was developed. Three major functions, including DNA extraction, amplification, and detection, are integrated into a portable case. This system mainly consists of (1) a specially designed 3D printed box for on-site reagent storage that can maintain low temperature (below 4°C) for 7.5 h at ambient temperature (35°C); (2) a custom device, called the IF-Device, for DNA amplification and detection of HLB, with an optimized optical structure, a sensitive signal processing circuit, and a precise temperature control algorithm with an accuracy of ±0.1°C; and (3) a battery-based power supply for the whole system. In a typical test using sodium fluorescein as a standard model, the results showed that the sensitivity of this system (1.0 nM) could easily meet the requirements of fluorescence biosensors. The feasibility of this homemade system was evaluated with samples extracted from infected citrus leaves based on the loop-mediated isothermal amplification (LAMP) method, and the limit of detection (LOD) was approximately 1.0 × 10-4 ng µL-1. The whole detection process for eight samples could be simultaneously accomplished within 40 min, and the results could be displayed on a smartphone in real-time. Moreover, the portable case is anti-interference, low cost, and only 2 kg in weight. Considering its sensitivity, stability, and portability, this highly integrated system possesses promising prospects for in-field detection. Keywords: Field detection, Fluorescence biosensor, Huanglongbing, Isothermal amplification, Sample-to-answer.

scholarly journals Parallel acoustic delay lines for photoacoustic tomography

2013 ◽  
Author(s):  
Murat Kaya Yapici ◽  
Chulhong Kim ◽  
Cheng-Chung Chang ◽  
Mansik Jeon ◽  
Zijian Guo ◽  
...  
Keyword(s):  
Photoacoustic Tomography ◽  
Delay Lines
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