scholarly journals Quantitative blood flow estimation in vivo by optical speckle image velocimetry: publisher's note

Optica ◽  
2021 ◽  
Author(s):  
Alexine Hart
Keyword(s):  
Blood Flow ◽  
Flow Estimation ◽  
Speckle Image ◽  
Image Velocimetry

scholarly journals Quantitative blood flow estimation in vivo by optical speckle image velocimetry

Optica ◽  
2021 ◽  
Author(s):  
Euiheon Chung ◽  
Muhammad Mohsin Qureshi ◽  
Yan Liu ◽  
Khuong Duy Mac ◽  
Minsung Kim ◽  
...  
Keyword(s):  
Blood Flow ◽  
Flow Estimation ◽  
Speckle Image ◽  
Image Velocimetry

scholarly journals Quantitative blood flow estimation in vivo by optical speckle image velocimetry

2021 ◽  
Author(s):  
Muhammad Mohsin Qureshi ◽  
Yan Liu ◽  
Khoung Duy Mac ◽  
Minsung Kim ◽  
Abdul Mohaimen Safi ◽  
...  
Keyword(s):  
Blood Flow ◽  
Optical Methods ◽  
High Temporal Resolution ◽  
Wide Field ◽  
Image Size ◽  
Speckle Image ◽  
Vector Map ◽  
Flow Vector ◽  
Image Velocimetry

Speckle based methods are popular non-invasive, label-free full-field optical techniques for imaging blood flow maps at single vessel resolution with a high temporal resolution. However, conventional speckle approach cannot provide an absolute velocity map with magnitude and direction. Here, we report a novel optical speckle image velocimetry (OSIV) technique for measuring the quantitative blood flow vector map by utilizing particle image velocimetry with speckle cross-correlations. We demonstrate that our OSIV instrument has a linearity range up to 7 mm/s, higher than conventional optical methods. Our method can measure the absolute flow vector map at up to 190 Hz without sacrificing the image size, and it eliminates the need for a high-speed camera/detector. We applied OSIV to image the blood flow in a mouse brain, and as a proof of concept, imaged the real-time dynamic changes in the cortical blood flow field during the stroke process in vivo. Our wide-field quantitative flow measurement OSIV method without the need of tracers provides a valuable tool for studying the healthy and diseased brain.

scholarly journals Cerebral blood flow estimation in vivo using local tissue reference functions

2009 ◽  
Vol 29 (1) ◽  
pp. 183-188 ◽  
Author(s):  
Jayme Cameron Kosior ◽  
Michael R. Smith ◽  
Robert Karl Kosior ◽  
Richard Frayne
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Flow Estimation ◽  
Local Tissue ◽  
Reference Functions

Microvascular features that suggest effectors of blood-flow regulation in the brain: Evidence by SEM of corrosion casts of intracerebral vessels

1990 ◽  
Vol 48 (3) ◽  
pp. 274-275
Author(s):  
Enrico D.F. Motti ◽  
Hans-Georg Imhof ◽  
Gazi M. Yasargil
Keyword(s):  
Blood Flow ◽  
Perfusion Pressure ◽  
Corrosion Casts ◽  
Cerebral Microcirculation ◽  
Pial Arteries ◽  
Random Occurrence ◽  
Brain Arteries ◽  
Homogeneous Network ◽  
The Brain

Physiologists have devoted most attention in the cerebrovascular tree to the arterial side of the circulation which has been subdivided in three levels: 1) major brain arteries which keep microcirculation constant despite changes in perfusion pressure; 2) pial arteries supposed to be effectors regulating microcirculation; 3) intracerebral arteries supposed to be deprived of active cerebral blood flow regulating devices.The morphological search for microvascular effectors in the cerebrovascular bed has been elusive. The opaque substance of the brain confines in vivo investigation to the superficial pial arteries. Most morphologists had to limit their observation to the random occurrence of a favorable site in the practically two-dimensional thickness of diaphanized histological sections. It is then not surprising most investigators of the cerebral microcirculation refer to an homogeneous network of microvessels interposed between arterioles and venules.We have taken advantage of the excellent depth of focus afforded by the scanning electron microscope (SEM) to investigate corrosion casts obtained injecting a range of experimental animals with a modified Batson's acrylic mixture.

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