Identifying/digital staining of diseased regions by monitoring disease specific marker molecules using Raman spectral libraries

2015 ◽  
Author(s):  
A. Pandya ◽  
J. Hilaneh ◽  
J.C. Kumaradas ◽  
A. Douplik
Keyword(s):  
Specific Marker ◽  
Spectral Libraries ◽  
Raman Spectral ◽  
Disease Specific

scholarly journals Familial multiple myeloma. Two more families

Open Medicine ◽  
2009 ◽  
Vol 4 (4) ◽  
pp. 501-505
Author(s):  
Judit Várkonyi ◽  
Péter Farkas ◽  
Júlia Tamáska ◽  
Tamás Masszi ◽  
László Gopcsa ◽  
...  
Keyword(s):  
Multiple Myeloma ◽  
Environmental Exposure ◽  
Enzyme Polymorphism ◽  
Hla Typing ◽  
Sibling Pair ◽  
Specific Marker ◽  
Sibling Pairs ◽  
Gstp1 Ile105val ◽  
Metabolizing Enzyme ◽  
Disease Specific

AbstractThe authors report on two multiple myeloma sibling pairs. In the absence of a known disease-specific marker one can only speculate on an explanation: is it because of inherited errors or is it related to the same environmental exposure, or both? In this study HLA typing and metabolizing enzyme polymorphism studies have been carried out with the aim of finding inherited similarities in the siblings or characteristics that might differ from the average population. Sibling pair 1 shared an HLA haplotype. Sibling pair 2 shared only HLA-B51, DR4, DRw53, DQ3. Sibling 1/1 was GSTT1 / GSTM1 null and GSTP1 Ile105Val; sibling 1/2 was a GSTT1 / GSTM1 heterozygote and GSTP1 Ile105Val; sibling 2/1 and 2/2 were GSTT1 heterozygotes and shared GSTM1 null / GSTP1 Ile105Ile. The siblings had identical light chain or heavy chain secretion, or both. The similarities found in the inherited factors together with the same environmental exposure in the siblings’ first 20 years of life imply that the development of the same disease cannot be a coincidence.

Advances in the Application of Array Detectors for Improved Chemical Analysis. Part 1. Comparison of Qualitative Analyses Using Large, Computer-Based Raman Spectral Libraries

ChemInform ◽  
2003 ◽  
Vol 34 (28) ◽  
Author(s):  
M. Bonner Denton ◽  
Roger P. Sperline ◽  
Jeffrey H. Giles ◽  
Daniel A. Gilmore ◽  
Carolyn J. S. Pommier ◽  
...  
Keyword(s):  
Chemical Analysis ◽  
Large Computer ◽  
Array Detectors ◽  
Computer Based ◽  
Spectral Libraries ◽  
Raman Spectral ◽  
Qualitative Analyses

scholarly journals The CSF3R T618I mutation as a disease-specific marker of atypical CML post allo-SCT

2014 ◽  
Vol 49 (6) ◽  
pp. 843-844 ◽  
Author(s):  
S E Langabeer ◽  
S L McCarron ◽  
K Haslam ◽  
M T O'Donovan ◽  
E Conneally
Keyword(s):  
Specific Marker ◽  
Atypical Cml ◽  
Disease Specific

Identification of candidate bacterial pathogens in ulcerative colitis using a disease-specific marker antibody

1998 ◽  
Vol 114 ◽  
pp. A953
Author(s):  
O. Cohavy ◽  
A.B. Tayebali ◽  
P.K. Phu ◽  
M.P. Eggena ◽  
D. Bruckner ◽  
...  
Keyword(s):  
Ulcerative Colitis ◽  
Bacterial Pathogens ◽  
Specific Marker ◽  
Disease Specific

Advances in the Application of Array Detectors for Improved Chemical Analysis, Part I. Comparison of Qualitative Analyses Using Large, Computer-Based Raman Spectral Libraries

2003 ◽  
Vol 56 (3) ◽  
pp. 117 ◽  
Author(s):  
M. Bonner Denton ◽  
Roger P. Sperline ◽  
Jeffrey H. Giles ◽  
Daniel A. Gilmore ◽  
Carolyn J. S. Pommier ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Large Computer ◽  
Analytical Technique ◽  
Minimal Sample ◽  
Array Detectors ◽  
Technical Advances ◽  
Computer Based ◽  
Spectral Libraries ◽  
Raman Spectral ◽  
Qualitative Analyses

Although a mature technique, Raman spectroscopy remains not widely used as a routine analytical technique. The advantages of Raman spectroscopy, such as minimal sample preparation and relatively uncomplicated spectra, combined with technical advances, including more stable diode lasers, higher quality filters, and better polychromators and array detectors, have led to a renaissance in sensitive and versatile Raman spectrometers. The lack of appropriate databases for routine analysis, which represents the last barrier to the technique's widespread use, is beginning to be overcome, as described in this review.

HLA-DQ2 and/or-DQ9 is associated with coeliac disease specific autoantibodies to tissue transglutaminase in families with thyrold autoimmunity

2001 ◽  
Vol 120 (5) ◽  
pp. A393-A393
Author(s):  
D SCHUPPAN ◽  
W DIETERICH ◽  
S HOFMANN ◽  
M HUEFNER ◽  
K USADEL ◽  
...  
Keyword(s):  
Coeliac Disease ◽  
Tissue Transglutaminase ◽  
Disease Specific ◽  
Hla Dq2

1140: Prognostic Nomogram for Disease-Specific Survival of Patients with Untreated Androgen Independent Prostate Cancer

2005 ◽  
Vol 173 (4S) ◽  
pp. 310-310
Author(s):  
Robert S. Svatek ◽  
Pierre I. Karakiewicz ◽  
Michael J. Shulman ◽  
Jose Karam ◽  
Paul Perrotte ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Disease Specific Survival ◽  
Disease Specific ◽  
Androgen Independent
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