Near-infrared emitting squaraine dyes for multiphoton fluorescence imaging with high 2PA cross sections

2011 ◽  
Author(s):  
Hyo-Yang Ahn ◽  
Sheng Yao ◽  
Xuhua Wang ◽  
Kevin D. Belfield
Keyword(s):  
Fluorescence Imaging ◽  
Cross Sections ◽  
Near Infrared ◽  
Squaraine Dyes

scholarly journals Near-Infrared-Emitting Squaraine Dyes with High 2PA Cross-Sections for Multiphoton Fluorescence Imaging

2012 ◽  
Vol 4 (6) ◽  
pp. 2847-2854 ◽  
Author(s):  
Hyo-Yang Ahn ◽  
Sheng Yao ◽  
Xuhua Wang ◽  
Kevin D. Belfield
Keyword(s):  
Fluorescence Imaging ◽  
Cross Sections ◽  
Near Infrared ◽  
Squaraine Dyes

Near‐Infrared‐II Nanomaterials for Fluorescence Imaging and Photodynamic Therapy

2021 ◽  
pp. 2002177
Author(s):  
Hongxin Lin ◽  
Zexi Lin ◽  
Konghua Zheng ◽  
Chenlu Wang ◽  
Lisheng Lin ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Fluorescence Imaging ◽  
Near Infrared

Lysosomal targeted NIR photosensitizer for photodynamic therapy and two-photon fluorescent imaging

2021 ◽  
Author(s):  
Ruiyuan Liu ◽  
Yuping Zhou ◽  
Di Zhang ◽  
Genghan He ◽  
Chuang Liu ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Fluorescence Imaging ◽  
Near Infrared ◽  
Fluorescent Imaging ◽  
High Fidelity ◽  
Design And Synthesis ◽  
Two Photon ◽  
Two Photon Fluorescence ◽  
Photon Fluorescence

Design and synthesis of near-infrared (NIR) emissive fluorophore for imaging of organelle and photodynamic therapy has received enormous attention. Hence, NIR emissive fluorophore of high-fidelity lysosome targeting, two-photon fluorescence imaging,...

Gram-scale synthesis of a neodymium chelate as a spectral CT and second near-infrared window imaging agent for visualizing the gastrointestinal tract in vivo

2021 ◽  
Author(s):  
Pengrui Zhuang ◽  
Ke Xiang ◽  
Xiangxi Meng ◽  
Guohe Wang ◽  
Ziyuan Li ◽  
...  
Keyword(s):  
Gastrointestinal Tract ◽  
Fluorescence Imaging ◽  
Large Scale ◽  
Near Infrared ◽  
Imaging Agent ◽  
Spectral Ct ◽  
Green Method ◽  
Infrared Window

A facile and green method was developed to fabricate Nd-DTPA on a large scale without byproducts for CT/spectral CT and NIR II fluorescence imaging of the gastrointestinal tract in vivo.

scholarly journals Near Infrared Fluorescence Imaging of Intraperitoneal Ovarian Tumors in Mice Using Erythrocyte-Derived Optical Nanoparticles and Spatially-Modulated Illumination

Cancers ◽  
2021 ◽  
Vol 13 (11) ◽  
pp. 2544
Author(s):  
Joshua M. Burns ◽  
Elise Shafer ◽  
Raviraj Vankayala ◽  
Vikas Kundra ◽  
Bahman Anvari
Keyword(s):  
Fluorescence Imaging ◽  
Cytoreductive Surgery ◽  
Animal Studies ◽  
Near Infrared ◽  
Gynecological Cancer ◽  
Ovarian Tumors ◽  
Structured Illumination ◽  
Spatial Frequencies ◽  
Imaging Probes ◽  
Intraoperative Fluorescence Imaging

Ovarian cancer is the deadliest gynecological cancer. Cytoreductive surgery to remove primary and intraperitoneal tumor deposits remains as the standard therapeutic approach. However, lack of an intraoperative image-guided approach to enable the visualization of all tumors can result in incomplete cytoreduction and recurrence. We engineered nano-sized particles derived from erythrocytes that encapsulate the near infrared (NIR) fluorochrome, indocyanine green, as potential imaging probes for tumor visualization during cytoreductive surgery. Herein, we present the first demonstration of the use of these nanoparticles in conjunction with spatially-modulated illumination (SMI), at spatial frequencies in the range of 0–0.5 mm−1, to fluorescently image intraperitoneal ovarian tumors in mice. Results of our animal studies suggest that the nanoparticles accumulated at higher levels within tumors 24 h post-intraperitoneal injection as compared to various other organs. We demonstrate that, under the imaging specifications reported here, use of these nanoparticles in conjunction with SMI enhances the fluorescence image contrast between intraperitoneal tumors and liver, and between intraperitoneal tumors and spleen by nearly 2.1, and 3.0 times, respectively, at the spatial frequency of 0.2 mm−1 as compared to the contrast values at spatially-uniform (non-modulated) illumination. These results suggest that the combination of erythrocyte-derived NIR nanoparticles and structured illumination provides a promising approach for intraoperative fluorescence imaging of ovarian tumor nodules at enhanced contrast.

Total thyroidectomy with intraoperative neural monitoring and near-infrared fluorescence imaging

2021 ◽  
Author(s):  
Diego Barbieri ◽  
Frédéric Triponez ◽  
Pietro Indelicato ◽  
Alessandro Vinciguerra ◽  
Matteo Trimarchi ◽  
...  
Keyword(s):  
Total Thyroidectomy ◽  
Fluorescence Imaging ◽  
Near Infrared ◽  
Near Infrared Fluorescence ◽  
Neural Monitoring ◽  
Near Infrared Fluorescence Imaging
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