Optofluidic in-fiber integrated surface-enhanced Raman spectroscopy detection based on a hollow optical fiber with a suspended core

2019 ◽  
Vol 44 (21) ◽  
pp. 5173
Author(s):  
Danheng Gao ◽  
Xinghua Yang ◽  
Pingping Teng ◽  
Zhihai Liu ◽  
Jun Yang ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Optical Fiber ◽  
Surface Enhanced Raman Spectroscopy ◽  
Surface Enhanced ◽  
Surface Enhanced Raman

Surface-enhanced Raman spectroscopy measurement of cancerous cells with optical fiber sensor

2014 ◽  
Vol 12 (s1) ◽  
pp. S13001-313003 ◽  
Author(s):  
Shupeng Liu Shupeng Liu ◽  
Lianxin Li Lianxin Li ◽  
Zhenyi Chen Zhenyi Chen ◽  
Na Chen Na Chen ◽  
Zhangmin Dai Zhangmin Dai ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Optical Fiber ◽  
Optical Fiber Sensor ◽  
Surface Enhanced Raman Spectroscopy ◽  
Fiber Sensor ◽  
Spectroscopy Measurement ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Cancerous Cells

scholarly journals Remote surface enhanced Raman spectroscopy imaging via a nanostructured optical fiber bundle

2009 ◽  
Vol 17 (26) ◽  
pp. 24030 ◽  
Author(s):  
Valérie Guieu ◽  
Patrick Garrigue ◽  
François Lagugné-Labarthet ◽  
Laurent Servant ◽  
Neso Sojic ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Optical Fiber ◽  
Fiber Bundle ◽  
Surface Enhanced Raman Spectroscopy ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Optical Fiber Bundle

Bacterial detection and differentiation via direct volatile organic compound sensing with surface enhanced Raman spectroscopy

2017 ◽  
Author(s):  
Caitlin S. DeJong ◽  
David I. Wang ◽  
Aleksandr Polyakov ◽  
Anita Rogacs ◽  
Steven J. Simske ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Bacterial Infections ◽  
Direct Detection ◽  
Point Of Care ◽  
Surface Enhanced Raman Spectroscopy ◽  
E Coli ◽  
Recent Emergence ◽  
Surface Enhanced ◽  
Volatile Organic ◽  
Surface Enhanced Raman

Through the direct detection of bacterial volatile organic compounds (VOCs), via surface enhanced Raman spectroscopy (SERS), we report here a reconfigurable assay for the identification and monitoring of bacteria. We demonstrate differentiation between highly clinically relevant organisms: <i>Escherichia coli</i>, <i>Enterobacter cloacae</i>, and <i>Serratia marcescens</i>. This is the first differentiation of bacteria via SERS of bacterial VOC signatures. The assay also detected as few as 10 CFU/ml of <i>E. coli</i> in under 12 hrs, and detected <i>E. coli</i> from whole human blood and human urine in 16 hrs at clinically relevant concentrations of 10<sup>3</sup> CFU/ml and 10<sup>4</sup> CFU/ml, respectively. In addition, the recent emergence of portable Raman spectrometers uniquely allows SERS to bring VOC detection to point-of-care settings for diagnosing bacterial infections.

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