Structure fits the purpose: photonic crystal fibers for evanescent-field surface-enhanced Raman spectroscopy

2010 ◽  
Vol 35 (4) ◽  
pp. 466 ◽  
Author(s):  
Maung Kyaw Khaing Oo ◽  
Yun Han ◽  
Jiri Kanka ◽  
Svetlana Sukhishvili ◽  
Henry Du
Keyword(s):  
Raman Spectroscopy ◽  
Photonic Crystal ◽  
Photonic Crystal Fibers ◽  
Surface Enhanced Raman Spectroscopy ◽  
Evanescent Field ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Crystal Fibers

scholarly journals Hollow-Core Photonic Crystal Fibers for Surface-Enhanced Raman Scattering Probes

2011 ◽  
Vol 2011 ◽  
pp. 1-11 ◽  
Author(s):  
Xuan Yang ◽  
Chao Shi ◽  
Rebecca Newhouse ◽  
Jin Z. Zhang ◽  
Claire Gu
Keyword(s):  
Photonic Crystal ◽  
Raman Scattering ◽  
Photonic Crystal Fibers ◽  
High Sensitivity ◽  
Surface Enhanced Raman Scattering ◽  
Hollow Core ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Enhanced Raman Scattering ◽  
Crystal Fibers

Photonic crystal fiber (PCF) sensors based on surface-enhanced Raman scattering (SERS) have become increasingly attractive in chemical and biological detections due to the molecular specificity, high sensitivity, and flexibility. In this paper, we review the development of PCF SERS sensors with emphasis on our recent work on SERS sensors utilizing hollow-core photonic crystal fibers (HCPCFs). Specifically, we discuss and compare various HCPCF SERS sensors, including the liquid-filled HCPCF and liquid-core photonic crystal fibers (LCPCFs). We experimentally demonstrate and theoretically analyze the high sensitivity of the HCPCF SERS sensors. Various molecules including Rhodamine B, Rhodamine 6G, human insulin, and tryptophan have been tested to show the excellent performance of these fiber sensors.

Towards Full-Length Accumulative Surface-Enhanced Raman Scattering-Active Photonic Crystal Fibers

2010 ◽  
Vol 22 (24) ◽  
pp. 2647-2651 ◽  
Author(s):  
Yun Han ◽  
Siliu Tan ◽  
Maung Kyaw Khaing Oo ◽  
Denis Pristinski ◽  
Svetlana Sukhishvili ◽  
...  
Keyword(s):  
Photonic Crystal ◽  
Raman Scattering ◽  
Photonic Crystal Fibers ◽  
Surface Enhanced Raman Scattering ◽  
Full Length ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Enhanced Raman Scattering ◽  
Crystal Fibers

Bacterial detection and differentiation via direct volatile organic compound sensing with surface enhanced Raman spectroscopy

2017 ◽  
Author(s):  
Caitlin S. DeJong ◽  
David I. Wang ◽  
Aleksandr Polyakov ◽  
Anita Rogacs ◽  
Steven J. Simske ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Bacterial Infections ◽  
Direct Detection ◽  
Point Of Care ◽  
Surface Enhanced Raman Spectroscopy ◽  
E Coli ◽  
Recent Emergence ◽  
Surface Enhanced ◽  
Volatile Organic ◽  
Surface Enhanced Raman

Through the direct detection of bacterial volatile organic compounds (VOCs), via surface enhanced Raman spectroscopy (SERS), we report here a reconfigurable assay for the identification and monitoring of bacteria. We demonstrate differentiation between highly clinically relevant organisms: <i>Escherichia coli</i>, <i>Enterobacter cloacae</i>, and <i>Serratia marcescens</i>. This is the first differentiation of bacteria via SERS of bacterial VOC signatures. The assay also detected as few as 10 CFU/ml of <i>E. coli</i> in under 12 hrs, and detected <i>E. coli</i> from whole human blood and human urine in 16 hrs at clinically relevant concentrations of 10<sup>3</sup> CFU/ml and 10<sup>4</sup> CFU/ml, respectively. In addition, the recent emergence of portable Raman spectrometers uniquely allows SERS to bring VOC detection to point-of-care settings for diagnosing bacterial infections.

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