Real-time measurement of in vitro flow by Fourier-domain color Doppler optical coherence tomography

2004 ◽  
Vol 29 (2) ◽  
pp. 171 ◽  
Author(s):  
Rainer A. Leitgeb ◽  
Leopold Schmetterer ◽  
Christoph K. Hitzenberger ◽  
Adolf F. Fercher ◽  
Fatma Berisha ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Real Time ◽  
Color Doppler ◽  
Time Measurement ◽  
Fourier Domain ◽  
Optical Coherence ◽  
Real Time Measurement ◽  
Doppler Optical Coherence Tomography

Real-time measurement of in-vitro and in-vivo blood flow with Fourier domain optical coherence tomography

2004 ◽  
Author(s):  
Rainer Leitgeb ◽  
Leopold Schmetterer ◽  
Wolfgang Drexler ◽  
Fatmire Berisha ◽  
Christoph K. Hitzenberger ◽  
...  
Keyword(s):  
Blood Flow ◽  
Optical Coherence Tomography ◽  
Real Time ◽  
Time Measurement ◽  
Fourier Domain ◽  
Optical Coherence ◽  
Real Time Measurement

Real-time in vivo color Doppler optical coherence tomography

2002 ◽  
Vol 7 (1) ◽  
pp. 123 ◽  
Author(s):  
Andrew M. Rollins ◽  
Siavash Yazdanfar ◽  
Jennifer K. Barton ◽  
Joseph A. Izatt
Keyword(s):  
Optical Coherence Tomography ◽  
Real Time ◽  
Color Doppler ◽  
Optical Coherence ◽  
Doppler Optical Coherence Tomography

Real-time, high velocity-resolution color Doppler optical coherence tomography

2002 ◽  
Vol 27 (1) ◽  
pp. 34 ◽  
Author(s):  
Volker Westphal ◽  
Siavash Yazdanfar ◽  
Andrew M. Rollins ◽  
Joseph A. Izatt
Keyword(s):  
Optical Coherence Tomography ◽  
Real Time ◽  
High Velocity ◽  
Color Doppler ◽  
Optical Coherence ◽  
High Velocity Resolution ◽  
Doppler Optical Coherence Tomography

scholarly journals Real-time assessment of retinal blood flow with ultrafast acquisition by color Doppler Fourier domain optical coherence tomography

2003 ◽  
Vol 11 (23) ◽  
pp. 3116 ◽  
Author(s):  
R. A. Leitgeb ◽  
L. Schmetterer ◽  
W. Drexler ◽  
A. F. Fercher ◽  
R. J. Zawadzki ◽  
...  
Keyword(s):  
Blood Flow ◽  
Optical Coherence Tomography ◽  
Real Time ◽  
Color Doppler ◽  
Retinal Blood Flow ◽  
Fourier Domain ◽  
Optical Coherence ◽  
Time Assessment

Doppler Optical Coherence Tomography: Real-Time Optical Sectioning for Microfluidics

2009 ◽  
Author(s):  
Yeh-Chan Ahn ◽  
Matthew Brenner ◽  
Zhongping Chen
Keyword(s):  
Optical Coherence Tomography ◽  
Real Time ◽  
Doppler Ultrasound ◽  
Acoustic Waves ◽  
Motion Artifacts ◽  
Fourier Domain ◽  
Optical Coherence ◽  
Cross Sectional ◽  
Measurable Velocity ◽  
Doppler Optical Coherence Tomography

Doppler optical coherence tomography (DOCT) is an emerging imaging modality demonstrated in 1991 for the first time and is a functional extension of optical coherence tomography (OCT) to including flow measurement. DOCT allows not only high-resolution, non-invasive, cross-sectional imaging but also simultaneous real-time visualization of sample structure and flow. DOCT is often compared to clinical Doppler ultrasound. However, the spatial resolution of clinical Doppler ultrasound is limited to approximately 100 μm due to the relatively long wavelength of acoustic waves. DOCT takes advantage of the short coherence length of broadband light sources in order to achieve cross-sectional images with micrometer (2–10 μm) scale resolution. DOCT is also superior to ultrasound in that DOCT is operated in non-contact-mode. The last four years have witnessed an era of technology revolution in DOCT, introduced by the Fourier-domain technology that shows tremendous advantage over time-domain DOCT. Fourier-domain Doppler optical coherence tomography (FDDOCT) instruments have higher imaging speed and higher system sensitivity which are able to overcome motion artifacts and enhance minimum measurable velocity, respectively. Because of the aforementioned merits, FDDOCT has a broad range of clinical applications including ophthalmology, cardiology, urology, etc with information of tissue microstructure and blood flow. However, FDDOCT has seldom been applied to diagnose microfluidic devices. In this keynote paper, system configuration, principle behind, and applications of FDDOCT for microfluidics will be covered.

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