scholarly journals The OpenFlexure Block Stage: sub-100 nm fibre alignment with a monolithic plastic flexure stage

2020 ◽  
Vol 28 (4) ◽  
pp. 4763 ◽  
Author(s):  
Qingxin Meng ◽  
Kerrianne Harrington ◽  
Julian Stirling ◽  
Richard Bowman
Keyword(s):  
2019 ◽  
Author(s):  
Hugo Krynauw ◽  
Jannik Buescher ◽  
Josepha Koehne ◽  
Loes Verrijt ◽  
Georges Limbert ◽  
...  

AbstractPurposeThe lack of long-term patency of synthetic vascular grafts currently available on the market has directed research towards improving the performance of small diameter grafts. Improved radial compliance matching and tissue ingrowth into the graft scaffold are amongst the main goals for an ideal vascular graft.MethodsBiostable polyurethane scaffolds were manufactured by electrospinning and implanted in subcutaneous and circulatory positions in the rat for 7, 14 and 28 days. Scaffold morphology, tissue ingrowth, and mechanical properties of the scaffolds were assessed before implantation and after retrieval.ResultsTissue ingrowth after 24 days was 96.5 ± 2.3% in the subcutaneous implants and 77.8 ± 5.4% in the circulatory implants. Over the 24 days implantation, the elastic modulus at 12% strain decreased by 59% in direction of the fibre alignment whereas it increased by 1379% transverse to the fibre alignment of the highly aligned scaffold of the subcutaneous implants. The lesser aligned scaffold of the circulatory graft implants exhibited an increase of the elastic modulus at 12% strain by 77% in circumferential direction.ConclusionBased on the observations, it is proposed that the mechanism underlying the softening of the highly aligned scaffold in the predominant fibre direction is associated with scaffold compaction and local displacement of fibres by the newly formed tissue. The stiffening of the scaffold, observed transverse to highly aligned fibres and for more a random fibre distribution, represents the actual mechanical contribution of the tissue that developed in the scaffold.


2020 ◽  
Vol 239 ◽  
pp. 107289 ◽  
Author(s):  
Ankit Baranwal ◽  
Prabhat K. Agnihotri ◽  
J.P. McGarry

2005 ◽  
Vol 38 (10) ◽  
pp. 1151-1160 ◽  
Author(s):  
T. Miri ◽  
M. Barigou ◽  
P.J. Fryer ◽  
P.W. Cox
Keyword(s):  

2008 ◽  
Vol 18 (7) ◽  
pp. 075033 ◽  
Author(s):  
W P Sassen ◽  
V A Henneken ◽  
M Tichem ◽  
P M Sarro

1957 ◽  
Vol 47 (1-2) ◽  
pp. 185-190
Author(s):  
Herbert Musurillo

The batch of papyrus fragments which were numbered P. Mich. Inv. 4800 was discovered, according to an attached note, right at the site of Kôm Ushîm (or Karanis) during the campaign carried out so efficiently in the year 1926 by the University of Michigan. Of the pieces which concern us here, all written in the same hand and on the same roll, we have three large fragments (i, ii, and iii, measuring 13·9 by 14·7 cm., 14·4 by 10·9 cm., and 7·7 by 5·5 cm. respectively) and twelve small ones (fragments a to 1). It is difficult either on the basis of content or of fibre-alignment to unite any of these fragments very closely; it may be said, however, that it is just possible that frag, iii may belong to the bottom of frag, i (col. i) on the left side.


2011 ◽  
Vol 38 (12) ◽  
pp. 1130-1136 ◽  
Author(s):  
Sahng G. Kim ◽  
Seong-Gon Kim ◽  
Bryon Viechnicki ◽  
Syngcuk Kim ◽  
Hyun-Duck Nah

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