scholarly journals Improving the detection limit for on-chip photonic sensors based on subwavelength grating racetrack resonators

2017 ◽  
Vol 25 (9) ◽  
pp. 10527 ◽  
Author(s):  
Lijun Huang ◽  
Hai Yan ◽  
Xiaochuan Xu ◽  
Swapnajit Chakravarty ◽  
Naimei Tang ◽  
...  
2018 ◽  
Vol 26 (25) ◽  
pp. 33005 ◽  
Author(s):  
Yu He ◽  
Yong Zhang ◽  
Hongwei Wang ◽  
Yikai Su

Sensors ◽  
2020 ◽  
Vol 20 (12) ◽  
pp. 3416 ◽  
Author(s):  
Nikolay Lvovich Kazanskiy ◽  
Svetlana Nikolaevna Khonina ◽  
Muhammad Ali Butt

In this paper, a racetrack ring resonator design based on a subwavelength grating double slot waveguide is presented. The proposed waveguide scheme is capable of confining the transverse electric field in the slots and the gaps between the grating segments. This configuration facilitates a large light–matter interaction which elevates the sensitivity of the device approximately 2.5 times higher than the one that can be obtained via a standard slot waveguide resonator. The best sensitivity of the design is obtained at 1000 nm/RIU by utilizing a subwavelength grating double slot waveguide of period 300 nm. The numerical study is conducted via 2D and 3D finite element methods. We believe that the proposed sensor design can play an important role in the realization of highly sensitive lab-on-chip sensors.


Nanophotonics ◽  
2017 ◽  
Vol 6 (4) ◽  
pp. 703-712 ◽  
Author(s):  
Daan Martens ◽  
Peter Bienstman

AbstractThe Mach-Zehnder interferometer (MZI) and the Vernier-cascade are highly responsive photonic sensors with large design freedom. They are therefore very suitable for interrogation through a broadband source and an on-chip spectral filter, a sensing scheme that is well equipped for point-of-care applications. In this work, the MZI is shown to outperform the Vernier-cascade through a better minimum detectable wavelength shift as well as a higher power efficiency, indicating its superiority in this sensing scheme. Fabricated MZIs yield bulk detection limits down to 8.8×10−7 refractive index units (RIU) in a point-of-care compatible measuring setup, indicating the potential of the proposed sensing scheme.


Author(s):  
Yali Gao ◽  
Guoqing Hu ◽  
Frank Y. H. Lin ◽  
Philip M. Sherman ◽  
Dongqing Li

A novel automatic electrokinetically-controlled immunoassay lab-on-a-chip was developed in this paper. The microchip was made of poly(dimethylsiloxane) (PDMS)/glass using photolithography and replica molding. The immunoassay technique using anti-Helicobacter pylori antibody was applied to detect H. pylori protein antigens. Rhodamine-labeled secondary antibody was employed for signal generation. Experiments were first conducted on a straight microchannel to prove the feasibility of an electrokinetically-driven immunoassay. The detection limit for the coating antigen was found to be 1 ng/μL. Automatic electrokinetically-controlled immunoassay experiments were further carried out on a microchannel network. Numerical simulation and experimental studies were combined for the first time to demonstrate an integrated, electrokinetically-controlled immunoassay lab-on-a-chip. The electrokinetically driven, time-dependent reagent delivery processes were simulated using finite element method (FEM). Fully automatic on-chip experiments were accomplished by sequentially changing the applied electric field. It was found that the lab-on-a-chip can realize much shorter assay time, reduced reagent consumptions and automation while the detection limit is better than the conventional colorimetric immunoassay.


2017 ◽  
Author(s):  
Lijun Huang ◽  
Hai Yan ◽  
Xiaochuan Xu ◽  
Swapnajit Chakravarty ◽  
Naimei Tang ◽  
...  

2021 ◽  
Author(s):  
Yue Wang ◽  
hao sun ◽  
Mostafa Khalil ◽  
Wei Dong ◽  
Ivana Gasulla Mestre ◽  
...  

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