scholarly journals A fiber optic probe design to measure depth- limited optical properties in-vivo with Low-coherence Enhanced Backscattering (LEBS) Spectroscopy

2012 ◽  
Vol 20 (18) ◽  
pp. 19643 ◽  
Author(s):  
Nikhil N. Mutyal ◽  
Andrew Radosevich ◽  
Bradley Gould ◽  
Jeremy D. Rogers ◽  
Andrew Gomes ◽  
...  
Keyword(s):  
Optical Properties ◽  
Fiber Optic ◽  
Probe Design ◽  
Fiber Optic Probe ◽  
Low Coherence ◽  
Enhanced Backscattering ◽  
Optic Probe

847m In Situ Rectal Low-Coherence Enhanced Backscattering Spectroscopy (Lebs) With a Fiber-Optic Probe Provides Accurate Risk Stratification for Colorectal Neoplasia

2010 ◽  
Vol 138 (5) ◽  
pp. S-113
Author(s):  
Hemant K. Roy ◽  
Nikhil Mutyal ◽  
Andrew Radosevich ◽  
Michael J. Goldberg ◽  
Ashish K. Tiwari ◽  
...  
Keyword(s):  
Risk Stratification ◽  
Fiber Optic ◽  
Colorectal Neoplasia ◽  
Fiber Optic Probe ◽  
Low Coherence ◽  
Enhanced Backscattering ◽  
Optic Probe

scholarly journals Effect of the Architecture of Fiber-Optic Probes Designed for Soluble Solid Content Prediction in Intact Sugar Beet Slices

Sensors ◽  
2019 ◽  
Vol 19 (13) ◽  
pp. 2995
Author(s):  
Ryad Bendoula ◽  
Arnaud Ducanchez ◽  
Ana Herrero-Langreo ◽  
Pablo Guerrero-Castro ◽  
Jean-Michel Roger ◽  
...  
Keyword(s):  
Sugar Beet ◽  
Fiber Optic ◽  
Scattered Light ◽  
Sugar Content ◽  
Probe Design ◽  
Fiber Optic Probe ◽  
Spectral Models ◽  
Technical Properties ◽  
Fiber Probes ◽  
Optic Probe

Sugar beet is the second biggest world contributor to sugar production and the only one grown in Europe. One of the main limitations for its competitiveness is the lack of effective tools for assessing sugar content in unprocessed sugar beet roots, especially in breeding programs. In this context, a dedicated near infrared (NIR) fiber-optic probe based approach is proposed. NIR technology is widely used for the estimation of sugar content in vegetable products, while optic fibers allow a wide choice of technical properties and configurations. The objective of this research was to study the best architecture through different technical choices for the estimation of sugar content in intact sugar beet roots. NIR spectral measurements were taken on unprocessed sugar beet samples using two types of geometries, single and multiple fiber-probes. Sugar content estimates were more accurate when using multiple fiber-probes (up to R2 = 0.93) due to a lesser disruption of light specular reflection. In turn, on this configuration, the best estimations were observed for the smallest distances between emitting and collecting fibers, reducing the proportion of multiply scattered light in the spectra. Error of prediction (RPD) values of 3.95, 3.27 and 3.09 were obtained for distances between emitting and collecting fibers of 0.6, 1.2 and 1.8 µm respectively. These high RPD values highlight the good predictions capacities of the multi-fiber probes. Finally, this study contributes to a better understanding of the effects of the technical properties of optical fiber-probes on the quality of spectral models. In addition, and beyond this specificity related to sugar beet, these findings could be extended to other turbid media for quantitative optical spectroscopy and eventually to validate considered fiber-optic probe design obtained in this experimental study.

A Chemometric Analysis for Evaluation of Early-Stage Cartilage Degradation by Infrared Fiber-Optic Probe Spectroscopy

2005 ◽  
Vol 59 (12) ◽  
pp. 1527-1533 ◽  
Author(s):  
Guiyang Li ◽  
Mary Thomson ◽  
Edward Dicarlo ◽  
Xu Yang ◽  
Bryan Nestor ◽  
...  
Keyword(s):  
Fiber Optic ◽  
Early Stage ◽  
Cartilage Degradation ◽  
Fiber Optic Probe ◽  
Replacement Surgery ◽  
Multiple Regions ◽  
Grading Scale ◽  
Optic Probe ◽  
Probe Spectroscopy

In vivo identification of early-stage cartilage degradation could positively impact disease progression in osteoarthritis, but to date remains a challenge. The primary goal of this study was to develop an infrared fiber-optic probe (IFOP) chemometric method using partial least squares (PLS1) to objectively determine the degree of cartilage degradation. Arthritic human tibial plateaus ( N = 61) were obtained during knee replacement surgery and analyzed by IFOP. IFOP data were collected from multiple regions of each specimen and the cartilage graded according to the Collins Visual Grading Scale of 0, 1, 2, or 3. These grades correspond to cartilage morphology that displayed normal, swelling or softening, superficially slight fibrillation, and deeper fibrillation or serious fibrillation, respectively. The model focused on detecting early cartilage degradation and therefore utilized data from grades 0, 1, and 2. The best PLS1 calibration utilized the spectral range 1733–984 cm−1, and independent validation of the model utilizing 206 spectra to create a model and 105 independent test spectra resulted in a correlation between the predicted and actual Collins grade of R2 = 0.8228 with a standard error of prediction of 0.258 with a PLS1 rank of 15 PLS factors. A preliminary PLS1 calibration that utilized a cross-validation technique to investigate the possibility of correlation with histological tissue grade (33 spectra from 18 tissues) resulted in R2 = 0.8408 using only eight PLS factors, a very encouraging outcome. Thus, the groundwork for use of IFOP-based chemometric determination of early cartilage degradation has been established.

Fiber-optic probe design and optical property recovery algorithm for optical biopsy of brain tissue

2013 ◽  
Vol 18 (10) ◽  
pp. 107004 ◽  
Author(s):  
Derek J. Cappon ◽  
Thomas J. Farrell ◽  
Qiyin Fang ◽  
Joseph E. Hayward
Keyword(s):  
Optical Property ◽  
Brain Tissue ◽  
Fiber Optic ◽  
Optical Biopsy ◽  
Probe Design ◽  
Fiber Optic Probe ◽  
Recovery Algorithm ◽  
Optic Probe

scholarly journals Lensed fiber-optic probe design for efficient photon collection in scattering media

2014 ◽  
Vol 6 (1) ◽  
pp. 191 ◽  
Author(s):  
Youngjae Ryu ◽  
Younghoon Shin ◽  
Dasol Lee ◽  
Judith Y. Altarejos ◽  
Euiheon Chung ◽  
...  
Keyword(s):  
Fiber Optic ◽  
Probe Design ◽  
Fiber Optic Probe ◽  
Scattering Media ◽  
Optic Probe ◽  
Photon Collection

scholarly journals A Novel Monte Carlo Approach for Diagnostic Fiber Optic Probe Design

2011 ◽  
Author(s):  
Adam R. Gardner ◽  
Carole K. Hayakawa ◽  
Jerome Spanier ◽  
Vasan Venugopalan
Keyword(s):  
Monte Carlo ◽  
Fiber Optic ◽  
Probe Design ◽  
Fiber Optic Probe ◽  
Monte Carlo Approach ◽  
Optic Probe
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