Controlled Synthesis of Gold Nanorods and Application to Brain Tumor Delineation

2011 ◽  
Author(s):  
Kevin Seekell ◽  
Christy Wilson ◽  
Hillel Price ◽  
Gerald Grant ◽  
Adam Wax
Keyword(s):  
Brain Tumor ◽  
Gold Nanorods ◽  
Controlled Synthesis ◽  
Tumor Delineation

Feasibility of Brain Tumor Delineation using Immunolabeled Gold Nanorods

2013 ◽  
Author(s):  
Kevin C. Seekell ◽  
Spencer Lewis ◽  
Christy Wilson ◽  
Gerald Grant ◽  
Adam P. Wax
Keyword(s):  
Brain Tumor ◽  
Gold Nanorods ◽  
Tumor Delineation

scholarly journals Feasibility study of brain tumor delineation using immunolabeled gold nanorods

2013 ◽  
Vol 4 (11) ◽  
pp. 2284 ◽  
Author(s):  
Kevin Seekell ◽  
Spencer Lewis ◽  
Christy Wilson ◽  
Shuqin Li ◽  
Gerald Grant ◽  
...  
Keyword(s):  
Brain Tumor ◽  
Feasibility Study ◽  
Gold Nanorods ◽  
Tumor Delineation

scholarly journals Gold Nanorods for Light-Based Lung Cancer Theranostics

2018 ◽  
Vol 19 (11) ◽  
pp. 3318 ◽  
Author(s):  
Oscar Knights ◽  
James McLaughlan
Keyword(s):  
Gold Nanorods ◽  
Photothermal Therapy ◽  
Continuous Wave ◽  
Low Cost ◽  
Laser System ◽  
Controlled Synthesis ◽  
Surface Plasmon Resonances ◽  
Plasmon Resonances ◽  
Theranostic Applications ◽  
Cancer Theranostics

Gold nanorods (AuNRs) have the potential to be used in photoacoustic (PA) imaging and plasmonic photothermal therapy (PPTT) due to their unique optical properties, biocompatibility, controlled synthesis, and tuneable surface plasmon resonances (SPRs). Conventionally, continuous-wave (CW) lasers are used in PPTT partly due to their small size and low cost. However, if pulsed-wave (PW) lasers could be used to destroy tissue then combined theranostic applications, such as PA-guided PPTT, would be possible using the same laser system and AuNRs. In this study, we present the effects of AuNR size on PA response, PW-PPTT efficacy, and PA imaging in a tissue-mimicking phantom, as a necessary step in the development of AuNRs towards clinical use. At equivalent NP/mL, the PA signal intensity scaled with AuNR size, indicating that overall mass has an effect on PA response, and reinforcing the importance of efficient tumour targeting. Under PW illumination, all AuNRs showed toxicity at a laser fluence below the maximum permissible exposure to skin, with a maximum of 80% cell-death exhibited by the smallest AuNRs, strengthening the feasibility of PW-PPTT. The theranostic potential of PW lasers combined with AuNRs has been demonstrated for application in the lung.

Aspect ratio controlled synthesis of gold nanorods

2003 ◽  
Vol 20 (6) ◽  
pp. 1145-1148 ◽  
Author(s):  
Sung Koo Kang ◽  
Soonwoo Chah ◽  
Chang Yeon Yun ◽  
Jongheop Yi
Keyword(s):  
Aspect Ratio ◽  
Gold Nanorods ◽  
Controlled Synthesis

scholarly journals Controlled synthesis of monodisperse gold nanorods with different aspect ratios in the presence of aromatic additives

2014 ◽  
Vol 16 (12) ◽  
Author(s):  
Yun Wang ◽  
Feihu Wang ◽  
Yuan Guo ◽  
Rongjun Chen ◽  
Yuanyuan Shen ◽  
...  
Keyword(s):  
Gold Nanorods ◽  
Controlled Synthesis ◽  
Aspect Ratios

Aspect-ratio-controlled synthesis of high-aspect-ratio gold nanorods in high-yield

2009 ◽  
Vol 9 (2) ◽  
pp. e140-e143 ◽  
Author(s):  
Won Min Park ◽  
Yun Suk Huh ◽  
Won Hi Hong
Keyword(s):  
Aspect Ratio ◽  
Gold Nanorods ◽  
High Aspect Ratio ◽  
High Yield ◽  
Controlled Synthesis

scholarly journals Dual-Modality Surface-Enhanced Resonance Raman Scattering and Multispectral Optoacoustic Tomography Nanoparticle Approach for Brain Tumor Delineation

Small ◽  
2018 ◽  
Vol 14 (23) ◽  
pp. 1800740 ◽  
Author(s):  
Volker Neuschmelting ◽  
Stefan Harmsen ◽  
Nicolas Beziere ◽  
Hannah Lockau ◽  
Hsiao-Ting Hsu ◽  
...  
Keyword(s):  
Brain Tumor ◽  
Raman Scattering ◽  
Resonance Raman ◽  
Resonance Raman Scattering ◽  
Dual Modality ◽  
Optoacoustic Tomography ◽  
Tumor Delineation ◽  
Surface Enhanced
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