IN VLVO OPTICAL MEASUREMENT OF TISSUE pH TO ASSESS BOWEL ISCHEMIA AND REPERFUSION DURING HEMORRHAGIC SHOCK

1998 ◽  
Author(s):  
Babs R. Soller ◽  
Songbiao Zhang ◽  
Joern Mueller ◽  
Juan Carlos Puyana
Keyword(s):  
Hemorrhagic Shock ◽  
Optical Measurement ◽  
Bowel Ischemia ◽  
Ischemia And Reperfusion ◽  
Tissue Ph

scholarly journals Total hepatic ischemia and reperfusion after state controlled hemorrhagic shock, with used of different solutions: effects of neutrophils sequestration in kidney of rats

2006 ◽  
Vol 21 (1) ◽  
pp. 31-37 ◽  
Author(s):  
Elcio Shiyoiti Hirano ◽  
Mario Mantovani ◽  
Rosana Celestina Morandin ◽  
Jarbas de Brito ◽  
Lilian Pavani
Keyword(s):  
Hemorrhagic Shock ◽  
Saline Solution ◽  
Renal Cortex ◽  
Ischemia And Reperfusion ◽  
Hepatic Ischemia ◽  
Mean Values ◽  
Physiologic Saline ◽  
Lactated Ringer's Solution ◽  
The Mean ◽  
Pringle’S Maneuver

PURPOSE: To evaluate and compare neutrophils sequestration in the renal cortex of rats, result of total hepatic ischemia and reperfusion after controlled hemorrhagic shock, with use of different electrolytic solutions. METHODS: Used 18 rats Wistar, males, adult, divided into three groups as the solution used to reanimation: Group PSS: physiologic saline solution; Group HSS: hypertonic saline hypertonic (7,5%) followed by lactated ringer's solution; Group LRS: lactated ringer's solution. All the animals were submitted to the bleeding controlled until mean arterial pressure (MAP) 40 mmHg, for 20 minutes. Performed volemic replacement until PAM=80 mmHg with the solution according the studied group, followed by laparotomy and Pringle's Maneuver for 15 minutes. The animals were accompanied until for two hours. To statistical comparisons between mean of neutrophils sequestration, in interstitium of the renal cortex, were made the tests One-way ANOVA and covariance analysis, adjusting itself for time of supervened. The hemodynamic parameters evaluated were: MAP, heat rate, cardiac index, vascular resistance system index. The analyzed metabolic variables were: pH, bicarbonate, base deficit and lactato, besides electrolytes. RESULTS: The mean values of supervened, in minutes, for group were: Group PSS 79,0±12,0; Group LRS 97,0±11,0; Group HSS 67,0±10. The mean values of neutrophils/field in the renal cortex were: Group PSS 0,55±0,68; Group LRS 1,68±0,53; Group HSS 1,33±0,43. When adjusted for time of supervened: Group PSS 0,55; Group LRS 1,62; Group HSS 1,39. There was statistically significant difference in neutrophils sequestration, between Group PSS regarding the others groups, using itself or not the adjustment by time of supervened (p=0,016 and p=0,0128). CONCLUSION: Both critical situations in this model, controlled hemorrhagic shock followed by Pringle's maneuver, promoted neutrophils sequestration in the interstitium renal of rat, and the physiologic saline solution demonstrated minor mean, differentiating statistically of the others solutions.

EARLY DIFFERENCE IN TISSUE PH AND MICROVASCULAR HEMODYNAMICS IN HEMORRHAGIC SHOCK RESUSCITATION USING POLYETHYLENE GLYCOL-ALBUMIN- AND HYDROXYETHYL STARCH-BASED PLASMA EXPANDERS

Shock ◽  
2005 ◽  
Vol 24 (1) ◽  
pp. 66-73 ◽  
Author(s):  
Pedro Cabrales ◽  
Parimala Nacharaju ◽  
Belur N Manjula ◽  
Amy G Tsai ◽  
Seetharama A Acharya ◽  
...  
Keyword(s):  
Polyethylene Glycol ◽  
Hemorrhagic Shock ◽  
Hydroxyethyl Starch ◽  
Tissue Ph ◽  
Plasma Expanders

Noninvasive NIR measurement of tissue pH to assess hemorrhagic shock in swine

1999 ◽  
Author(s):  
Babs R. Soller ◽  
Songbiao Zhang ◽  
Ronald H. Micheels ◽  
Juan C. Puyana
Keyword(s):  
Hemorrhagic Shock ◽  
Tissue Ph

Directly measured tissue pH is an earlier indicator of splanchnic acidosis than tonometric parameters during hemorrhagic shock in swine

2000 ◽  
Vol 28 (7) ◽  
pp. 2557-2562 ◽  
Author(s):  
Juan Carlos Puyana ◽  
Babs R. Soller ◽  
Bhairavi Parikh ◽  
Stephen O. Heard
Keyword(s):  
Hemorrhagic Shock ◽  
Tissue Ph
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